Abstract: A conjugated composition and methods of using the same for treatment of a living cell, are provided. The conjugated composition includes a nucleic acid sequence directly or indirectly conjugated to at least one N-Acetylgalactosamine (GalNAc) molecule, or to a derivative of a GalNAc molecule. The conjugation is provided by a linker. The conjugated composition is structured to enable the at least one GalNAc molecule or derivative to deliver the nucleic acid sequence into a cell, for example, into a liver cell. The nucleic acid sequence can be a therapeutic supercoiled DNA minicircle that has a therapeutic gene for delivery to the cell.

Abstract: The present invention relates to proppants which can be used to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more proppants of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the proppants of the present invention are further disclosed, as well as methods of making the proppants.

Abstract: The present invention relates to proppants which can be used to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more proppants of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the proppants of the present invention are further disclosed, as well as methods of making the proppants.

Abstract: In a method of encapsulating information in a database, a message may be partitioned into a plurality of object class entries within the database. Each of the object class entries may constitute a portion of an object class from a plurality of object classes having a given hierarchy within the database. One or more pointers may be generated; the pointers point to at least one of the plurality of object class entries. The object class entries may be stored in non-adjacent storage locations within the database, with at least one of the plurality of object class entries stored in association with the generated at least one pointer such that the at least one pointer points to a higher-level object class entry, as determined by the object class hierarchy, than the at least one object class entry stored in association with the pointer.

Abstract: The present invention relates to proppants which can be used to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more proppants of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the proppants of the present invention are further disclosed, as well as methods of making the proppants.