Patents by Inventor Christopher Cullander

Christopher Cullander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the iontophoretic non-invasive determination of the in vivo concentration level of an inorganic or organic substance
    Patent number: 6714815
    Abstract: The present invention relates to an vitro device for the removal of ionized substances from a membrane sample without mechanical penetration, which device comprises: (a) a positive electrode; (b) a negative electrode, and (c) electrical insulation between subpart (a) and (b), wherein the positive electrode, and the negative electrode, and electrical insulation are positioned on the same side of the membrane sample. The present invention also relates to a device for the removal of or delivery of ionized substances to a mammal through intact skin or mucosal membrane without mechanical penetration, which device comprises: (a) a positive electrode, (b) a negative electrode, and (c) an electrically insulating material between subpart (a) and (b), wherein the positive electrode, negative electrode and insulating material are physically positioned so that each present a common surface of the device for contact with the same surface of the skin or mucosal membrane of the mammal.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: March 30, 2004
    Assignee: The Regents of the University of California
    Inventors: Richard Guy, Girish Rao, Christopher Cullander, Robert S. Hinz, Peretz Glikfeld
  • METHOD FOR THE IONTOPHORETIC NON-INVASIVE DETERMINATION OF THE IN VIVO CONCENTRATION LEVEL OF AN INORGANIC OR ORGANIC SUBSTANCE
    Publication number: 20040006262
    Abstract: The present invention relates to an vitro device for the removal of ionized substances from a membrane sample without mechanical penetration, which device comprises:
    Type: Application
    Filed: January 13, 2003
    Publication date: January 8, 2004
    Inventors: Richard Guy, Girish Rao, Christopher Cullander, Robert S. Hinz, Peretz Glikfeld
  • Introduction of modifying agents into skin by electroporation
    Patent number: 5911223
    Abstract: A method of modifying epidermis for transport of a material by electroporation includes applying to epidermis an agent that, upon entry into the epidermis, will modify the epidermis to thereby cause and altered rate of transport of a material across the epidermis. Typically, the altered rate will be an increased rate of transport. The epidermis is electroporated, whereby at least a portion of the modifying agent enters the electroporated epidermis, thereby modifying the epidermis to cause an altered rate of transport of a material across the epidermis. In another embodiment, the modifying agent can modify the epidermis to enable measurement and/or monitoring of physiological conditions or change within or beneath the epidermis. The modifying agents can also be employed to facilitate discharge of fluids from within an organism, such as by providing pathways for discharge of fluids from a tumor.
    Type: Grant
    Filed: August 9, 1996
    Date of Patent: June 15, 1999
    Assignees: Massachusetts Institute of Technology, The Regents of the University of California
    Inventors: James C. Weaver, Tani Chen, Christopher Cullander, Richard Guy, Robert S. Langer, Thomas E. Zewert, Uwe Pliquett, Rita Vanbever, Mark R. Prausnitz
  • Method for the iontophoretic non-invasive determination of the in vivo concentration level of glucose
    Patent number: 5730714
    Abstract: The present invention relates to an vitro device for the removal of ionized substances from a membrane sample without mechanical penetration, which device comprises:(a) a positive electrode;(b) a negative electrode, and(c) electrical insulation between subpart (a) and (b), wherein the positive electrode, and the negative electrode, and electrical insulation are positioned on the same side of the membrane sample.The present invention also relates to a device for the removal of or delivery of ionized substances to a mammal through intact skin or mucosal membrane without mechanical penetration, which device comprises: (a) a positive electrode, (b) a negative electrode, and (c) an electrically insulating material between subpart (a) and (b), wherein the positive electrode, negative electrode and insulating material are physically positioned so that each present a common surface of the device for contact with the same surface of the skin or mucosal membrane of the mammal.
    Type: Grant
    Filed: September 26, 1994
    Date of Patent: March 24, 1998
    Assignee: The Regents of the University of California
    Inventors: Richard Guy, Girish Rao, Peretz Glikfeld, Christopher Cullander, Robert S. Hinz
  • Device for iontophoretic non-invasive sampling or delivery of substances
    Patent number: 5279543
    Abstract: The present invention relates to an vitro device for the removal of ionized substances from a membrane sample without mechanical penetration, which device comprises:(a) a positive electrode;(b) a negative electrode, and(c) electrical insulation between subpart (a) and (b), wherein the positive electrode, and the negative electrode, and electrical insulation are positioned on the same side of the membrane sample.The present invention also relates to a device for the removal of or delivery of ionized substances to a mammal through intact skin or mucosal membrane without mechanical penetration, which device comprises: (a) a positive electrode, (b) a negative electrode, and (c) an electrically insulating material between subpart (a) and (b), wherein the positive electrode, negative electrode and insulating material are physically positioned so that each present a common surface of the device for contact with the same surface of the skin or mucosal membrane of the mammal.
    Type: Grant
    Filed: April 30, 1992
    Date of Patent: January 18, 1994
    Assignee: The Regents of The University of California
    Inventors: Peretz Glikfeld, Christopher Cullander, Robert S. Hinz, Richard H. Guy