Abstract: Disclosed herein is a method for forming an anti-microbial layer on an apparatus. Also disclosed is a method for improving the anti-bacterial properties of a titanium device coated with titanium-nitride (TiN). Also disclosed is a medical apparatus comprising an anti-microbial layer prepared by the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: Disclosed herein is a method for forming an anti-microbial layer on an apparatus. Also disclosed is a method for improving the anti-bacterial properties of a titanium device coated with titanium-nitride (TiN). Also disclosed is a medical apparatus comprising an anti-microbial layer prepared by the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: The invention generally relates to keto ester compositions and methods for using the compositions. In one aspect, the invention provides a method for preventing a metabolic-related condition or disorder in a subject, the method comprising the step of providing to the subject an effective amount of at least one keto ester compound or a pharmaceutically acceptable salt thereof, and an effective amount of at least one maltodextrin compound, thereby preventing the metabolic-related condition or disorder. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: The present disclosure provides for methods, devices, and compositions for controlling factors involved in the healing of lesions. The methods, devices, and composition include a first therapeutic agent which includes an amount of MCP-1 and/or osteopontin effective to promote recruitment of macrophages to the lesion site. In additional embodiments, there is further provided a second therapeutic agent which includes an inhibitor of at least one of IL-17A, CXCL1, or IL-6 to promote polarization of an amount of the macrophages to M2 phenotype macrophages at the lesion site.

Abstract: Disclosed are magnetic field shielding devices designed to attenuate magnetic fields that may interact with or otherwise have an adverse effect on implantable electronic devices.

Abstract: Compositions, formulas, methods of making, mixing and applying insecticide formulations to different surfaces such as but not limited to interior surfaces of ovitraps, on walls and on chips and tiles to produce a texturized surface to allow for better transfer of the insecticidal active ingredients to insects, such as mosquitoes and the like, which land on or crawl on the surfaces, resulting in faster insect mortality rates. The texture of the insecticidal residue provides better transfer of the insecticidal active ingredients to insects that land on or crawl on the surface, resulting in faster insect mortality. The textured residue also enhances desirable surface characteristics for landing of mosquitoes and potentially other insects.

Abstract: Disclosed herein is a method for forming an anti-microbial layer on an apparatus. Also disclosed is a method for improving the anti-bacterial properties of a titanium device coated with titanium-nitride (TiN). Also disclosed is a medical apparatus comprising an anti-microbial layer prepared by the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: Compositions, formulas, methods of making, mixing and applying insecticide formulations to different surfaces such as but not limited to interior surfaces of ovitraps, on walls and on chips and tiles to produce a texturized surface to allow for better transfer of the insecticidal active ingredients to insects, such as mosquitoes and the like, which land on or crawl on the surfaces, resulting in faster insect mortality rates. The texture of the insecticidal residue provides better transfer of the insecticidal active ingredients to insects that land on or crawl on the surface, resulting in faster insect mortality. The textured residue also enhances desirable surface characteristics for landing of mosquitoes and potentially other insects.

Abstract: A flexible catheter is inserted into the esophagus to cool or warm the esophagus, particularly during certain procedures which can tend to change the temperature in the area of the esophagus. The catheter is inserted through the mouth and throat to a position, for example, proximate the heart, but within the esophagus. A thermally conductive gel is injected into the esophagus where it is immobilized by the one or more balloons. A coolant is pumped through a coolant tube affixed to the catheter, where it exchanges heat with the conductive gel.

Abstract: Compositions, formulas, methods of making, mixing and applying insecticide formulations to different surfaces such as but not limited to interior surfaces of ovitraps, on walls and on chips and tiles to produce a texturized surface to allow for better transfer of the insecticidal active ingredients to insects, such as mosquitoes and the like, which land on or crawl on the surfaces, resulting in faster insect mortality rates. The texture of the insecticidal residue provides better transfer of the insecticidal active ingredients to insects that land on or crawl on the surface, resulting in faster insect mortality. The textured residue also enhances desirable surface characteristics for landing of mosquitoes and potentially other insects.

Abstract: Provided herein are laparoscopic tissue removal systems, components, and uses thereof.

Abstract: The present disclosure provides arginine-releasing restorative dental materials, methods of making the dental materials, and methods of using arginine-releasing restorative dental materials to and/or to treat, prevent and/or control caries, such as caries associated with dental work.

Abstract: Provided herein are laparoscopic tissue removal systems, components, and uses thereof.

Abstract: The present invention relates to the detection of markers in exhaled breath, wherein the detection of the presence or absence of the marker(s) in exhaled breath is used to assess various clinical data, including patient adherence in taking the medication and patient enzymatic (metabolic) competence in metabolizing the medication. An embodiment of the invention comprises a parent therapeutic agent labeled with a marker, where upon metabolism (e.g., via enzymatic action) of the therapeutic agent, the marker becomes volatile or semi-volatile and is present in the breath. In certain related embodiments, the marker contain a deuterium label, which is also present in the breath upon metabolism of the therapeutic agent. In another embodiment of the invention, the therapeutic agent is associated with a taggant (that may be either labeled or unlabeled with deuterium), which in turn will generate a marker in the breath that is easily measurable.

Abstract: Devices that provide timed-release of target compounds absorbed by, or otherwise integrated into, an external housing. The external housing absorbs and facilitates volatilization of the released compound. A permeable cover can be employed as a regulating mechanism to control the rate volatilization from the external housing. One or more reservoirs containing target compound can be contained within one or more internal chambers of the external housing. The one or more reservoirs can release the target compound for absorption by the external housing and/or to make contact with one or more other reservoirs so as to compromise the other reservoirs and release target compound within. A wick can be employed in certain embodiments to transfer target compound from the internal chamber to the external housing to be volatilized. Continued or sequential release of target compound to recharged the external housing achieves a zero order release rate from the external housing.

Abstract: Devices that provide timed-release of target compounds absorbed by, or otherwise integrated into, an external housing. The external housing absorbs and facilitates volatilization of the released compound. A permeable cover can be employed as a regulating mechanism to control the rate volatilization from the external housing. One or more reservoirs containing target compound can be contained within one or more internal chambers of the external housing. The one or more reservoirs can release the target compound for absorption by the external housing and/or to make contact with one or more other reservoirs so as to compromise the other reservoirs and release target compound within. A wick can be employed in certain embodiments to transfer target compound from the internal chamber to the external housing to be volatilized. Continued or sequential release of target compound to recharged the external housing achieves a zero order release rate from the external housing.

Abstract: The present invention relates to the detection of markers in exhaled breath, wherein the detection of the presence or absence of the marker(s) in exhaled breath is used to assess various clinical data, including patient adherence in taking the medication and patient enzymatic (metabolic) competence in metabolizing the medication. An embodiment of the invention comprises a parent therapeutic agent labeled with a marker, where upon metabolism (e.g., via enzymatic action) of the therapeutic agent, the marker becomes volatile or semi-volatile and is present in the breath. In certain related embodiments, the marker contain a deuterium label, which is also present in the breath upon metabolism of the therapeutic agent. In another embodiment of the invention, the therapeutic agent is associated with a taggant (that may be either labeled or unlabeled with deuterium), which in turn will generate a marker in the breath that is easily measurable.

Abstract: The subject invention provides novel devices and methods for the detection of the presence and/or activity of proteases in biological samples.

Abstract: This invention relates to compositions and methods related to biocompatible conductive inks. In a preferred embodiment the inks are printable onto biocompatible substrates and are used in the creation of biocompatible medical devices, in general, the inks comprise a plurality of particles. In one embodiment, the particles have a particle surface and an agent on the particle surface, the agent configured to prevent the particles from agglomerating when the particles are in a solution, the agent also configured to allow adjacent particle surfaces to be in contact when the particles are not in the solution due to an opening in the agent.

Abstract: The present invention relates to a method of delivery of a therapeutic agent to a target cell, the method comprising targeting particles comprising the therapeutic agent to the cell using magnetic means to apply a magnetic force to said particles so as to tend to move said particles towards said magnetic means and at the same time moving said magnetic means.