Patents by Inventor Christopher D. Fuller

Christopher D. Fuller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to detect the end-point for PCR DNA amplification using an ionically labeled probe and measuring impedance change
    Patent number: 7157232
    Abstract: Impedance measurements are used to detect the end-point for PCR DNA amplification. A pair of spaced electrodes are located on a surface of a microfluidic channel and an AC or DC voltage is applied across the electrodes to produce an electric field. An ionically labeled probe will attach to a complementary DNA segment, and a polymerase enzyme will release the ionic label. This causes the conductivity of the solution in the area of the electrode to change. This change in conductivity is measured as a change in the impedance been the two electrodes.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: January 2, 2007
    Assignee: The Regents of the University of California
    Inventors: Robin R. Miles, Phillip Belgrader, Christopher D. Fuller