Patents by Inventor Christopher D. J. Pearce

Christopher D. J. Pearce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for determining the purity of chemically synthesized nucleic acids
    Patent number: 9273149
    Abstract: This application describes an antibody that specifically binds to a synthetic oligomer (e.g., an oligonucleotide or oligopeptide) having a organic protecting group covalently bound thereto, which antibody does not bind to that synthetic oligomer when the organic protecting group is not covalently bound thereto. Methods of making and using such antibodies are also disclosed, along with cells for making such antibodies and articles carrying immobilized oligomers that can be used in assay procedures with such antibodies.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: March 1, 2016
    Assignees: Veri-Q, Inc., North Carolina State University
    Inventors: Paul F. Agris, Christopher D. J. Pearce, Lloyd G. Mitchell
  • Methods and compositions for determining the purity of chemically synthesized nucleic acids
    Patent number: 8697355
    Abstract: This application describes an antibody that specifically binds to a synthetic oligomer (e.g., an oligonucleotide or oligopeptide) having a organic protecting group covalently bound thereto, which antibody does not bind to that synthetic oligomer when the organic protecting group is not covalently bound thereto. Methods of making and using such antibodies are also disclosed, along with cells for making such antibodies and articles carrying immobilized oligomers that can be used in assay procedures with such antibodies.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: April 15, 2014
    Assignee: North Carolina State University
    Inventors: Paul F. Agris, Christopher D. J. Pearce, Lloyd G. Mitchell
  • Methods and compositions for determining the purity of chemically synthesized nucleic acids
    Patent number: 8323910
    Abstract: This application describes an antibody that specifically binds to a synthetic oligomer (e.g., an oligonucleotide or oligopeptide) having a organic protecting group covalently bound thereto, which antibody does not bind to that synthetic oligomer when the organic protecting group is not covalently bound thereto. Methods of making and using such antibodies are also disclosed, along with cells for making such antibodies and articles carrying immobilized oligomers that can be used in assay procedures with such antibodies.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: December 4, 2012
    Assignee: North Carolina State University
    Inventors: Paul F. Agris, Christopher D. J. Pearce, Lloyd G. Mitchell
  • Methods and compositions for determining the purity of chemically synthesized nucleic acids
    Patent number: 8173377
    Abstract: This application describes an antibody that specifically binds to a synthetic oligomer (e.g., an oligonucleotide or oligopeptide) having a organic protecting group covalently bound thereto, which antibody does not bind to that synthetic oligomer when the organic protecting group is not covalently bound thereto. Methods of making and using such antibodies are also disclosed, along with cells for making such antibodies and articles carrying immobilized oligomers that can be used in assay procedures with such antibodies.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: May 8, 2012
    Assignee: North Carolina State University
    Inventors: Paul F. Agris, Christopher D. J. Pearce, Lloyd G. Mitchell
  • Methods and compositions for determining the purity of and purifying chemically synthesized nucleic acids
    Patent number: 8076461
    Abstract: An antibody microarray is described comprising a plurality of antibodies immobilized on a substrate, wherein each antibody specifically binds to a synthetic oligomer (e.g., an oligonucleotide or oligopeptide) having an organic protecting group covalently bound thereto, which antibody does not bind to that synthetic oligomer when the organic protecting group is not covalently bound thereto. Methods of making and using such antibodies are disclosed, along with cells for making such antibodies. Methods of making and using such antibody microarrays are also disclosed.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: December 13, 2011
    Assignee: Proteome Sciences PLC
    Inventors: Christopher D. J. Pearce, Lloyd G. Mitchell
  • Methods and compositions for determining the purity of chemically synthesized nucleic acids
    Patent number: 7901892
    Abstract: This application describes an antibody that specifically binds to a synthetic oligomer (e.g., an oligonucleotide or oligopeptide) having a organic protecting group covalently bound thereto, which antibody does not bind to that synthetic oligomer when the organic protecting group is not covalently bound thereto. Methods of making and using such antibodies are also disclosed, along with cells for making such antibodies and articles carrying immobilized oligomers that can be used in assay procedures with such antibodies.
    Type: Grant
    Filed: July 8, 2002
    Date of Patent: March 8, 2011
    Assignee: North Carolina State University
    Inventors: Paul F. Agris, Christopher D. J. Pearce, Lloyd G. Mitchell