Patents by Inventor Christopher D. Kulczar

Christopher D. Kulczar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INJECTABLE PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
    Publication number: 20230310386
    Abstract: The present invention relates to injectable compositions comprising the combination of an isoxazoline compound as well as a physiologically active macrocyclic lactone such as moxidectin.
    Type: Application
    Filed: May 19, 2021
    Publication date: October 5, 2023
    Applicant: Intervet Inc.
    Inventors: Brenda L. Valle Colon, Keith Freehauf, Christopher D. Kulczar, Frank Guerino
  • PYRAZOLE PHARMACEUTICAL COMPOSITION
    Publication number: 20230070369
    Abstract: A pharmaceutical composition of pyrazole compound and a surfactant and a method of using the same to treat atopic dermatitis.
    Type: Application
    Filed: December 18, 2020
    Publication date: March 9, 2023
    Applicant: Intervet Inc.
    Inventors: Chad D. Brown, Christopher D. Kulczar, Chen-Chao Wang, Michelle H. Fung
  • A PHARMACEUTICAL COMPOSITION OF A PYRAZOLE COMPOUND DISPERSED IN A POLYMER MATRIX
    Publication number: 20230062746
    Abstract: A pharmaceutical composition of pyrazole compound dispersed in a polymer matrix and a method of using the same to treat atopic dermatitis.
    Type: Application
    Filed: December 18, 2020
    Publication date: March 2, 2023
    Applicant: Intervet Inc.
    Inventors: Christopher D. Kulczar, Luke Ryan Schenck, Yongjun Li, Alfred C.F. Rumondor
  • INJECTABLE PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
    Publication number: 20220296564
    Abstract: An injectable pharmaceutical composition comprising an isoxazoline compound of Formula (I), or a salt or N-oxide and moxidectin microspheres and a method of preventing or treating a parasite infestation using the same.
    Type: Application
    Filed: May 1, 2020
    Publication date: September 22, 2022
    Applicant: Intervet Inc.
    Inventors: Brenda L. Valle Colon, Keith A. Freehauf, Frank Guerino, Christopher D. Kulczar, Brian Carrillo
  • BLOOD BRAIN BARRIER MODELS AND METHODS TO GENERATE AND USE THE SAME
    Publication number: 20210140947
    Abstract: The present disclosure generally relates to a process to prepare a cell culture system that mimics the structure of blood brain barrier (BBB) and are useful to study the functions thereof. In particular, the present invention relates to a direct-contact coculture and triculture systems prepared by plating BMECs on a pre-formed lawn of coculture of astrocytes and pericytes on the apical surface of a culture-chamber to achieve a truly direct contact triculture model for BBB. The cell culture systems disclosed herein are also useful for studying the functions of the blood brain barrier and predicting the efficacy and potential toxicity of a drug candidate.
    Type: Application
    Filed: December 18, 2020
    Publication date: May 13, 2021
    Applicant: Purdue Research Foundation
    Inventors: Gregory T. Knipp, Aimable Ngendahimana, Christopher D. Kulczar, Kelsey E. Lubin, Monika Lavan
  • Blood brain barrier models and methods to generate and use the same
    Patent number: 10877026
    Abstract: The present disclosure generally relates to a process to prepare a cell culture system that mimics the structure of blood brain barrier (BBB) and are useful to study the functions thereof. In particular, the present invention relates to a direct-contact coculture and triculture systems prepared by plating BMECs on a pre-formed lawn of coculture of astrocytes and pericytes on the apical surface of a culture-chamber to achieve a truly direct contact triculture model for BBB. The cell culture systems disclosed herein are also useful for studying the functions of the blood brain barrier and predicting the efficacy and potential toxicity of a drug candidate.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: December 29, 2020
    Assignee: Purdue Research Foundation
    Inventors: Gregory T. Knipp, Aimable Ngendahimana, Christopher D. Kulczar, Kelsey E. Lubin, Monika Lavan
  • BLOOD BRAIN BARRIER MODELS AND METHODS TO GENERATE AND USE THE SAME
    Publication number: 20180067103
    Abstract: The present disclosure generally relates to a process to prepare a cell culture system that mimics the structure of blood brain barrier (BBB) and are useful to study the functions thereof. In particular, the present invention relates to a direct-contact coculture and triculture systems prepared by plating BMECs on a pre-formed lawn of coculture of astrocytes and pericytes on the apical surface of a culture-chamber to achieve a truly direct contact triculture model for BBB. The cell culture systems disclosed herein are also useful for studying the functions of the blood brain barrier and predicting the efficacy and potential toxicity of a drug candidate.
    Type: Application
    Filed: September 7, 2017
    Publication date: March 8, 2018
    Applicant: Purdue Research Foundation
    Inventors: Gregory T. Knipp, Aimable Ngendahimana, Christopher D. Kulczar, Kelsey E. Lubin, Monika Lavan