Patents by Inventor Christopher D. Saudek

Christopher D. Saudek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Early detection of diabetes
    Patent number: 9250248
    Abstract: The present invention is based on the discovery that hexosamine, and in particular the dynamic O-GlcNAcylation of proteins (modification of proteins by the sugar N-acetylglucosamine) both causes insulin-resistance (a hallmark of type II diabetes) and is responsible for glucose toxicity in the disease. Accordingly, the invention provides methods of diagnosing a subject as having or at risk of having pre-diabetes or diabetes. Also provided are methods of characterizing hyperglycemia in a subject, methods of identifying a protein as being associated with hyperglycemia, and kits for detecting pre-diabetes or diabetes.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: February 2, 2016
    Assignee: The Johns Hopkins University
    Inventors: Gerald W. Hart, Kyoungsook Park, Christopher D. Saudek, Zihao Wang
  • Early Detection of Diabetes
    Publication number: 20100330594
    Abstract: The present invention is based on the discovery that hexosamine, and in particular the dynamic O-GlcNAcylation of proteins (modification of proteins by the sugar N-acetylglucosamine) both causes insulin-resistance (a hallmark of type II diabetes) and is responsible for glucose toxicity in the disease. Accordingly, the invention provides methods of diagnosing a subject as having or at risk of having pre-diabetes or diabetes. Also provided are methods of characterizing hyperglycemia in a subject, methods of identifying a protein as being associated with hyperglycemia, and kits for detecting pre-diabetes or diabetes.
    Type: Application
    Filed: October 31, 2007
    Publication date: December 30, 2010
    Inventors: Gerald W. Hart, Kyoungsook Park, Christopher D. Saudek, Zihao Wang