Patents by Inventor Christopher D. Wolin

Christopher D. Wolin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • m-RNA purification
    Patent number: 5614391
    Abstract: A method and kit for purification of m-RNA from a cell are disclosed. Guanidine containing moieties, at high molarity, are use to quickly lyse the cell. They also act to inhibit RNase activity. Without the need for isolation of total RNA, the lysate can then be directly purified from the lysate using oligo dT (or U) by reducing the guanidine concentration via a dilution step.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 25, 1997
    Assignee: Pharmacia P.L. Biochemicals, Inc.
    Inventors: Phillip P. Franciskovich, Christopher D. Wolin
  • M-RNA purification
    Patent number: 5459253
    Abstract: A method kit for purification of m-RNA from a cell are disclosed. Guanidine containing moieties, at high molarity, are use to quickly lyse the cell. They also act to inhibit RNase activity. Without the need for isolation of total RNA, the lysate can then be directly purified from the lysate using oligo dT (or U) by reducing the guanidine concentration via a dilution step.
    Type: Grant
    Filed: May 2, 1994
    Date of Patent: October 17, 1995
    Assignee: Pharmacia P-L Biochemicals Inc.
    Inventors: Christopher D. Wolin, Phillip P. Franciskovich