Abstract: A surgical trajectory alignment device is disclosed, including an alignment trajectory guide holding portion shaped to receive and secure an alignment trajectory guide along a longitudinal patient entry axis, the longitudinal patient entry axis falling within a plane. The surgical trajectory alignment device further includes a first alignment trajectory guide holding portion activator operable to rotate an alignment trajectory guide secured by an alignment arm holding portion within the plane; and a second alignment trajectory guide holding portion activator operable to translate an alignment trajectory guide secured by the alignment arm holding portion in a direction away from the plane.

Abstract: A surgical trajectory alignment device is disclosed, including an alignment trajectory guide holding portion shaped to receive and secure an alignment trajectory guide along a longitudinal patient entry axis, the longitudinal patient entry axis falling within a plane. The surgical trajectory alignment device further includes a first alignment trajectory guide holding portion activator operable to rotate an alignment trajectory guide secured by an alignment arm holding portion within the plane; and a second alignment trajectory guide holding portion activator operable to translate an alignment trajectory guide secured by the alignment arm holding portion in a direction away from the plane.

Abstract: A guide catheter shaft is formed from an inner tube structure and a multilayer sheath around the inner tube structure. The multilayer sheath includes an intermediate sheath and a shrink tube layer. The intermediate sheath is disposed around the inner tube and realized from a melt-processible first polyether-block amide material. The shrink tube layer is disposed around the intermediate sheath and realized from a different second polyether-block amide (e.g. a cross-linked polyether-block amide material) having a shrink temperature range greater than a melt temperature range of the first polyether-block amide material. The resulting structure is heated at a temperature within the shrink temperature range such that the outer shrink tube layer shrinks and the intermediate layer melts to thereby bond the multilayer sheath to the inner tube.

Abstract: A guide catheter includes a hollow elongate shaft defining a channel. The hollow elongate shaft (or a segment thereof) includes an inner tube and a multilayer sheath formed around the inner tube. The multilayer sheath includes an intermediate layer derived from a melt-processible first polyether-block amide material (e.g., PEBAX®) and an outer layer derived from a different second polyether-block amide (e.g. a cross-linked polyether-block amide material). Reinforcing material (such as a braid of reinforcing filament) may be part of the multilayer sheath. The second polyether-block amide layer of the outer layer provides a shrink tube with a shrink temperature range greater than melt temperature range of the first polyether-block amide material of the intermediate layer.