Patents by Inventor Christopher Davies

Christopher Davies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7833767
    Abstract: The present invention is directed to variant polypeptides having enhanced ketoreductase activity and/or thermostability for use in the stereospecific reduction of ketones. In addition, the present invention is directed to polynucleotides that encode the ketoreductase polypeptides, including codon optimized versions of the polynucleotides which provide for enhanced expression in host cells. In another aspect, the present invention is directed to nucleotide constructs, vectors and host cells that are transformed with polynucleotides of the present invention.
    Type: Grant
    Filed: October 8, 2009
    Date of Patent: November 16, 2010
    Assignee: Codexis, Inc.
    Inventors: S. Christopher Davis, Gjalt W. Huisman, Stephane J. Jenne, Anke Krebber, Lisa Marie Newman
  • Patent number: 7824898
    Abstract: The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
    Type: Grant
    Filed: August 11, 2004
    Date of Patent: November 2, 2010
    Assignee: Codexis, Inc.
    Inventors: S. Christopher Davis, Richard John Fox, Gjalt W. Huisman, Vesna Gavrilovic, Lisa Marie Newman
  • Patent number: 7820767
    Abstract: The present invention relates to a new aromatic polyimide composition containing an aromatic polyimide and a polyarylene of a specific type, and to articles and parts of articles made thereof.
    Type: Grant
    Filed: March 6, 2007
    Date of Patent: October 26, 2010
    Assignee: Solvay Advanced Polymers, L.L.C.
    Inventors: Mohammad Jamal El-Hibri, Leslie J. Myrick, David B. Thomas, Roy L. Carter, Nikica Maljkovic, Christopher Davis, Scott A. Harding
  • Publication number: 20100266757
    Abstract: In hot ambient conditions (particularly in climates having strong sunshine) vehicle glazing panels can reach high temperatures frequently in excess of 50° C. and on occasions up to 90° C. plus. In such high temperature conditions it is a known problem that small glazing panel breaks or cracks can become elongated (or result in shattering of the glazing panel) when stresses are applied to the glazing panel. The invention provides a method of repairing a flaw (such as a crack or break) in a vehicle glazing panel by first, wetting the surface of the glazing panel in the vicinity of the flaw and then generating a forced air flow to enhance evaporation of the wetted glazing panel, and subsequently conduction a repair process on the flaw.
    Type: Application
    Filed: July 4, 2008
    Publication date: October 21, 2010
    Applicant: BELRON HUNGARY KFT - ZUG BRANCH
    Inventors: André Segers, Christopher Davies
  • Patent number: 7816111
    Abstract: The present invention is directed to glucose dehydrogenase (GDH) polypeptides that have enhanced GDH activity and/or thermostability relative to the backbone wild-type glucose dehydrogenase polypeptide. In addition, the present invention is directed to a polynucleotide that encodes for the GDH polypeptides of the present invention, to nucleic acid sequences comprising the polynucleotides, to expression vectors comprising the polynucleotides operatively linked to a promoter, to host cells transformed to express the GDH polypeptides, and to a method for producing the GDH polypeptides of the present invention.
    Type: Grant
    Filed: August 11, 2004
    Date of Patent: October 19, 2010
    Assignee: Codexis, Inc.
    Inventors: S. Christopher Davis, Stephane J. Jenne, Anke Kebber, Lisa Marie Newman
  • Patent number: 7807423
    Abstract: The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hydroxybutyric acid derivatives by ketoreductase-catalyzed conversion of 4-halo-3-ketobutyric acid derivatives The present invention also provides methods and compositions for preparing vicinal cyano, hydroxyl substituted carboxylic acid esters.
    Type: Grant
    Filed: August 10, 2006
    Date of Patent: October 5, 2010
    Assignee: Codexis, Inc.
    Inventors: S. Christopher Davis, John H. Grate, David R. Gray, John M. Gruber, Gjalt W. Huisman, Steven K. Ma, Lisa M. Newman, Roger Sheldon, Li A Wang
  • Publication number: 20100231707
    Abstract: A method of investigating a glazing panel is disclosed in which a first investigation image of a target zone of the glazing panel is captured and a second investigation image of the target zone is captured. Image data from the first and second investigation images are combined to provide an output representative of the condition of the glazing panel at the target zone. The two investigation images are taken using respectively a black and a white background on the other side of the glazing panel.
    Type: Application
    Filed: April 22, 2008
    Publication date: September 16, 2010
    Inventors: Christopher Davies, André Segers
  • Patent number: 7783428
    Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.
    Type: Grant
    Filed: March 3, 2003
    Date of Patent: August 24, 2010
    Assignee: Maxygen, Inc.
    Inventors: Claes Gustafsson, Sridhar Govindarajan, Robin A. Emig, Richard John Fox, Ajoy K. Roy, Jeremy S. Minshull, S. Christopher Davis, Anthony R. Cox, Phillip A. Patten, Linda A. Castle, Daniel L. Siehl, Rebecca Lynne Gorton, Teddy Chen
  • Publication number: 20100187248
    Abstract: The present invention provides an apparatus, kit and method for dispensing lids one at a time in a sanitary and effective manner. A stack of lids is placed inside a tube and substantially held in the tube by a cover piece. Preferably the cover piece is concave in shape and is opposed by a concave platform that biases the stack of lids towards said cover piece. The bottommost lid of the stack is available for dispensing while the next lid in the stack is restrained in place, preferably by elements associated with the cover piece.
    Type: Application
    Filed: March 9, 2006
    Publication date: July 29, 2010
    Applicant: THE COLMAN GROUP, INC.
    Inventors: Amy Popp, Michael Young, Paul Omdoll, Christopher Davis, Robert Fuller
  • Patent number: 7751986
    Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: July 6, 2010
    Assignee: Maxygen, Inc.
    Inventors: Claes Gustafsson, Sridhar Govindarajan, Robin A. Emig, Richard John Fox, Ajoy K. Roy, Jeremy S. Minshull, S. Christopher Davis, Anthony R. Cox, Phillip A. Patten, Linda A. Castle, Daniel L. Siehl, Rebecca Lynne Gorton, Teddy Chen
  • Publication number: 20100167345
    Abstract: The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
    Type: Application
    Filed: October 5, 2009
    Publication date: July 1, 2010
    Applicant: CODEXIS, INC.
    Inventors: S. Christopher Davis, Richard John Fox, Gjalt W. Huisman, Vesna Gavrilovic, Lisa Marie Newman
  • Patent number: 7747391
    Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: June 29, 2010
    Assignee: Maxygen, Inc.
    Inventors: Claes Gustafsson, Sridhar Govindarajan, Robin A. Emig, Richard John Fox, Ajoy K. Roy, Jeremy S. Minshull, S. Christopher Davis, Anthony R. Cox, Phillip A. Patten, Linda A. Castle, Daniel L. Siehl, Rebecca Lynne Gorton, Teddy Chen
  • Publication number: 20100137305
    Abstract: The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Application
    Filed: September 18, 2009
    Publication date: June 3, 2010
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Hayley Binch, Stephen Young, Christopher Davis, Michael Mortimore, John Studley, Daniel Robinson, Michael O'Donnell, Dean Boyall, Joanne Pinder, Simon Everitt, Julian Golec
  • Publication number: 20100028972
    Abstract: The present invention is directed to variant polypeptides having enhanced ketoreductase activity and/or thermostability for use in the stereospecific reduction of ketones. In addition, the present invention is directed to polynucleotides that encode the ketoreductase polypeptides, including codon optimized versions of the polynucleotides which provide for enhanced expression in host cells. In another aspect, the present invention is directed to nucleotide constructs, vectors and host cells that are transformed with polynucleotides of the present invention.
    Type: Application
    Filed: October 8, 2009
    Publication date: February 4, 2010
    Applicant: CODEXIS, INC.
    Inventors: S. Christopher Davis, Gjalt W. Huisman, Stephane J. Jenne, Anke Krebber, Lisa Marie Newman
  • Patent number: 7654770
    Abstract: A marking sphere dispensing apparatus for dispensing fluid-assisted marking spheres into pavement marking materials applied to a surface has a frame defining a marking sphere receptacle, a valve seat defining an opening between the marking sphere receptacle and an expulsion duct. A plunger is disposed coaxially to the longitudinal axis of the dispensing apparatus and defines an internal fluid passage for providing pressurized fluid. The plunger is moveable in a longitudinal direction within the marking sphere dispensing frame between a first position at which a plunger head of the plunger is seated against the valve seat to close the opening, and a second position at which the plunger head is axially offset from the valve seat to define a marking sphere inlet gap across the opening. A method for applying marking spheres uses the marking sphere dispensing apparatus.
    Type: Grant
    Filed: August 21, 2008
    Date of Patent: February 2, 2010
    Assignee: Potters Industries Inc.
    Inventors: Kevin E. Hall, Christopher Davies, Thomas Still, Keith Wolos, Kenneth Grimbilas
  • Publication number: 20100023316
    Abstract: A participant response system comprises a plurality of handsets for allowing a participant of an event to input a response. Each handset comprises a wireless handset having a keyboard for allowing a user to input a response. The handsets are configurable either as a participant response handset to allow a participant to enter a response, or as a base station.
    Type: Application
    Filed: October 6, 2009
    Publication date: January 28, 2010
    Inventors: Anthony Knowles, Christopher Davies, Andrew Cornall
  • Publication number: 20100023984
    Abstract: In one embodiment, a method comprises identifying, by a device, an addressable media stream selected for presentation by a user; identifying, by the device, a user input that is input by the user during presentation of the addressable media stream to the user, the user input identified relative to an identified position within the addressable media stream; defining by the device a media clip from the addressable media stream based on determining the user input demonstrates a favorable affinity by the user toward the identified position, the defining including the device selecting a media clip start position within the addressable media stream and that precedes the identified position, and the device selecting a media clip end position that follows the identified position; and creating by the device a summary media clip of the addressable media stream that includes at least the media clip.
    Type: Application
    Filed: July 28, 2008
    Publication date: January 28, 2010
    Inventors: John Christopher DAVI, Glenn Thomas Millican, III
  • Publication number: 20100016518
    Abstract: Blend (B) comprising: at least one aromatic polycarbonate (P1), and at least one polyarylene (P2), more than 50 wt. % of the recurring units thereof are optionally substituted arylene groups [recurring units (R2)], each of said recurring units (R2) being linked by each of its two ends to two other optionally substituted arylene groups via a direct C—C linkage, and said recurring units (R2) being a mix (M) consisting of: between 0 and 75 mole %, based on the total number of moles of recurring units (R2), of rigid rod-forming arylene units (R2a), optionally substituted by at least one monovalent substituting group, with between 25 and 100 mole %, based on the total number of moles of recurring units (R2), of kink-forming arylene units (R2b), optionally substituted by at least one monovalent substituting group. Article or part of an article comprising the blend (B).
    Type: Application
    Filed: March 6, 2007
    Publication date: January 21, 2010
    Applicant: SOLVAY ADVANCED POLYMERS, L.L.C.
    Inventors: Mohammad Jamal El-Hibri, Leslie J. Myrick, David B. Thomas, Roy L. Carter, Nikica Maljkovic, Christopher Davis, Scott A. Harding
  • Publication number: 20090317297
    Abstract: An analyte test strip for accepting diverse bodily fluid sample volumes includes a first insulating layer, a second insulating layer disposed above the first insulating layer, and a third insulating layer disposed below the first insulating layer. The third insulating layer has a platform portion that extends beyond the first and second insulating layers and an upper surface. The analyte test strip also has a patterned spacer layer positioned between the first and second layers. The patterned spacer layer defines a channel between the first and second insulating layers that has a sample-receiving chamber, a first port proximate the platform portion and a second port at an outer edge of the analyte test strip. Moreover, the first port and the second port are in fluidic communication with the sample-receiving chamber.
    Type: Application
    Filed: June 24, 2008
    Publication date: December 24, 2009
    Inventors: John Mahoney, Caroline Chu, Herb Perasso, Susan Tannenbaum, Janice Jones, Koon-Wah Leong, John Christopher Davis
  • Publication number: 20090317847
    Abstract: A method for determining (e.g., detecting and/or measuring the concentration of) an analyte in a bodily fluid sample includes obtaining a bodily fluid sample, applying the bodily fluid sample to an analyte test strip, transferring the applied bodily fluid sample to a sample-receiving chamber of the analyte test strip, and determining an analyte in the bodily fluid sample. The analyte test strip employed in the method includes a first port in fluidic communication with the sample-receiving chamber and proximate a platform portion of the analyte test strip. Moreover, the platform portion is configured to receive a first (relatively large) bodily fluid sample of at least 5 micro-liters and transfer at least a portion of the first bodily fluid sample to the sample-receiving chamber via the first port.
    Type: Application
    Filed: June 24, 2008
    Publication date: December 24, 2009
    Inventors: John Mahoney, Caroline Chu, Herb Perasso, Susan Tannenbaum, Janice Jones, Koon-Wah Leong, John Christopher Davis