Patents by Inventor Christopher DesJardins

Christopher DesJardins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF IMMUNOTHERAPY AND MICROBIOME MODULATION TO TREAT CANCER
    Publication number: 20240148803
    Abstract: Provided herein are methods and compositions for the treatment of various types of cancers by modulating the microbiome to effect or enhance the efficacy of immunotherapy. Also provided herein are methods of determining a response to an immunotherapy by identifying if a subject has a favorable microbial profile. Further provided herein are methods of determining a donor whose feces are useful for fecal matter transfer.
    Type: Application
    Filed: February 18, 2022
    Publication date: May 9, 2024
    Applicant: Seres Therapeutics, Inc.
    Inventors: Christopher B. FORD, Elizabethh HALVORSEN, Christopher DESJARDINS, Kankana BARDHAN, Swarma Deepa PANDIAN
  • Method for determining a dwell volume of a chromatographic system
    Patent number: 11709085
    Abstract: Described is a method for determining a dwell volume of a liquid chromatography system and a liquid chromatography system that can determined the system dwell volume. The method includes mixing a flow of a first solvent with a flow of a second solvent to form a solvent mixture. The flows of the first and second solvents are decreased and increased, respectively, to generate a gradient composition. A system pressure of the liquid chromatography system is measured to determine a pressure trace defined as the measured system pressure as a function of time. The dwell volume of the system is determined from a time delay determined between the gradient composition at the mixing location and the pressure trace. The method can be performed with a liquid chromatography system having a chromatographic column or a flow restrictor used in place of the chromatographic column.
    Type: Grant
    Filed: August 19, 2020
    Date of Patent: July 25, 2023
    Assignee: Waters Technologies Corporation
    Inventors: Jason F. Hill, Martin Gilar, Abhijit Tarafder, Christopher DesJardins
  • TREATMENT OF A CANCER BY MICROBIOME MODULATION
    Publication number: 20210361721
    Abstract: Methods are provided for identifying donors of fecal matter that can improve a subject's response to a checkpoint inhibitor in the treatment of cancer. Methods and compositions are also provided for using donated fecal matter in the treatment of cancer.
    Type: Application
    Filed: March 28, 2019
    Publication date: November 25, 2021
    Inventors: Jennifer WORTMAN, Diao LIYANG, Christopher DESJARDINS, Georgios MARNELLOS, Matthew HENN, Jennifer WARGO, Vancheswaran GOPALAKRISHNAN
  • METHOD FOR DETERMINING A DWELL VOLUME OF A CHROMATOGRAPHIC SYSTEM
    Publication number: 20210055149
    Abstract: Described is a method for determining a dwell volume of a liquid chromatography system and a liquid chromatography system that can determined the system dwell volume. The method includes mixing a flow of a first solvent with a flow of a second solvent to form a solvent mixture. The flows of the first and second solvents are decreased and increased, respectively, to generate a gradient composition. A system pressure of the liquid chromatography system is measured to determine a pressure trace defined as the measured system pressure as a function of time. The dwell volume of the system is determined from a time delay determined between the gradient composition at the mixing location and the pressure trace. The method can be performed with a liquid chromatography system having a chromatographic column or a flow restrictor used in place of the chromatographic column.
    Type: Application
    Filed: August 19, 2020
    Publication date: February 25, 2021
    Inventors: Jason F. Hill, Martin Gilar, Abhijit Tarafder, Christopher DesJardins