Abstract: Methods and apparatus for interfaces to manage inter-regional connectivity for direct network peerings. A system may include a connectivity coordinator, a first resource collection in a first geographical zone and a second resource collection in a second geographical zone. The coordinator implements a programmatic interface defining connectivity operations. The coordinator receives a request via the interface to establish a logically isolated network path to the second resource collection on behalf of a client that has a dedicated physical link set up to connect to the first resource collection. In response to the request, the coordinator performs one or more configuration operations to enable traffic to flow from the client's network to the second resource collection over a logically isolated network path using the dedicated physical link.

Abstract: A mechanical stepper and method of incrementally actuating a device. An insert is placed within a housing. The housing has a cavity and a stepper sleeve located within the cavity. The stepper sleeve includes a first stop member having an equilibrium position defined by a first equilibrium diameter and a second stop member having an equilibrium position defined by a second equilibrium diameter less than the first equilibrium diameter. The insert including a first protrusion. The insert moves through the housing, and motion of the insert through the housing is incrementally restricted by changing a diameter of the first stop member and a diameter of the second stop member via the first protrusion.

Abstract: A mechanical stepper and method of incrementally actuating a device. An insert is placed within a housing. The housing has a cavity and a stepper sleeve located within the cavity. The stepper sleeve includes a first stop member having an equilibrium position defined by a first equilibrium diameter and a second stop member having an equilibrium position defined by a second equilibrium diameter less than the first equilibrium diameter. The insert including a first protrusion. The insert moves through the housing, and motion of the insert through the housing is incrementally restricted by changing a diameter of the first stop member and a diameter of the second stop member via the first protrusion.

Abstract: A mechanical stepper and method of incrementally actuating a device. An insert is placed within a housing. The housing has a cavity and a stepper sleeve located within the cavity. The stepper sleeve includes a first stop member having an equilibrium position defined by a first equilibrium diameter and a second stop member having an equilibrium position defined by a second equilibrium diameter less than the first equilibrium diameter. The insert including a first protrusion. The insert moves through the housing, and motion of the insert through the housing is incrementally restricted by changing a diameter of the first stop member and a diameter of the second stop member via the first protrusion.

Abstract: A mechanical stepper and method of incrementally actuating a device. An insert is placed within a housing. The housing has a cavity and a stepper sleeve located within the cavity. The stepper sleeve includes a first stop member having an equilibrium position defined by a first equilibrium diameter and a second stop member having an equilibrium position defined by a second equilibrium diameter less than the first equilibrium diameter. The insert including a first protrusion. The insert moves through the housing, and motion of the insert through the housing is incrementally restricted by changing a diameter of the first stop member and a diameter of the second stop member via the first protrusion.

Abstract: The present invention relates to compositions comprising antibodies or fragments thereof that immunospecifically bind to one or more antigens of a flavivirus, particularly of West Nile Virus (WNV), and methods for preventing, treating or ameliorating symptoms associated with a flavivirus, particularly of West Nile Virus (WNV), infection utilizing said compositions. In particular, the present invention relates to methods for preventing, treating or ameliorating symptoms associated with WNV infection, said methods comprising administering to a human subject an effective amount of one or more antibodies or fragments thereof that immunospecifically bind to a WNV antigen. The present invention also relates to detectable or diagnostic compositions comprising antibodies or fragments thereof that immunospecifically bind to a WNV antigen and methods for detecting or diagnosing WNV infection utilizing said compositions.

Abstract: A selectively released well tool anchor has a tubular wicker shoe cage and a tubular setting sleeve in sliding assembly over a tubular mandrel. The wicker shoe cage confines a plurality of independent wicker shoes. The tubular setting sleeve has a conical slip face that is loosely meshed with the shoe cage by a plurality of collet fingers extended from the conical slip face into meshed engagement with detents in the shoe cage. The collet fingers are secured within the detents for well run-in by calibrated shear fasteners. An axial translation of the setting sleeve toward the shoe cage by shearing the fasteners displaces the wicker shoes outwardly for inside wall penetration. The wicker shoes are disengaged from the wall by axial translation of the cage from the sleeve to engage mutual abutment faces on the cage and shoes.

Abstract: A selectively released well packer is set between a pair of anchor shoe assemblies. Each assembly comprises a tubular setting sleeve having finger projections meshed with an anchor shoe cage. Wicker shoes are confined by the shoe cage. The packer seal and shoes are set by an axial translation of one shoe cage toward the other driven by a hydraulic sleeve piston. The packer is released by cutting the mandrel and pulling up on the tubing string. The uphole shoe cage is secured to the mandrel with limited axial freedom. Upward translation of the uphole portion of the severed mandrel therefore disengages the uphole anchor shoes and the packer seal. A buttress thread section of the mandrel engages a corresponding thread on the downhole setting sleeve to sequentially release the downhole anchor shoe.

Abstract: A selectively released well tool anchor has a tubular wicker shoe cage and a tubular setting sleeve in sliding assembly over a tubular mandrel. The wicker shoe cage confines a plurality of independent wicker shoes. The tubular setting sleeve has a conical slip face that is loosely meshed with the shoe cage by a plurality of collet fingers extended from the conical slip face into meshed engagement with detents in the shoe cage. The collet fingers are secured within the detents for well run-in by calibrated shear fasteners. Slip faces on the several wicker shoes are aligned with the conical slip face to effect a radial displacement of the wicker shoes by an axial translation of the setting sleeve relative to the shoe cage. However, no relative axial translation may occur until sufficient axial compressive force between the shoe cage and setting sleeve is imposed to shear the calibrated fasteners.

Abstract: A selectively released well tool anchor has a tubular wicker shoe cage and a tubular setting sleeve in sliding assembly over a tubular mandrel. The wicker shoe cage confines a plurality of independent wicker shoes. The tubular setting sleeve has a conical slip face that is loosely meshed with the shoe cage by a plurality of collet fingers extended from the conical slip face into meshed engagement with detents in the shoe cage. The collet fingers are secured within the detents for well run-in by calibrated shear fasteners. Slip faces on the several wicker shoes are aligned with the conical slip face to effect a radial displacement of the wicker shoes by an axial translation of the setting sleeve relative to the shoe cage. However, no relative axial translation may occur until sufficient axial compressive force between the shoe cage and setting sleeve is imposed to shear the calibrated fasteners.