Patents by Inventor Christopher Donald Southan

Christopher Donald Southan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy
    Patent number: 7314742
    Abstract: The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.
    Type: Grant
    Filed: April 18, 2005
    Date of Patent: January 1, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Colin Houston MacPhee, David Graham Tew, Christopher Donald Southan, Deirdre Mary Bernadette Hickey, Israel Simon Gloger, Geoffrey Mark Prouse Lawrence, Simon Quentyn John Rice
  • Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy
    Patent number: 7045329
    Abstract: The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.
    Type: Grant
    Filed: August 3, 2001
    Date of Patent: May 16, 2006
    Assignee: SmithKline Beecham plc
    Inventors: Colin Houston MacPhee, David Graham Tew, Christopher Donald Southan, Deirdre Mary Bernadette Hickey, Israel Simon Gloger, Geoffrey Mark Prouse Lawrence, Simon Quentyn John Rice
  • MPROT12 polynucleotides and methods thereof
    Publication number: 20030088085
    Abstract: MPROT12 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing MPROT12 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Application
    Filed: March 2, 2001
    Publication date: May 8, 2003
    Inventors: Christopher Donald Southan, Joanne Rachel Evans
  • Novel compounds
    Publication number: 20020183269
    Abstract: The UPROT02 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing UPROT02 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Application
    Filed: January 22, 2001
    Publication date: December 5, 2002
    Inventors: Christopher Donald Southan, Trudi Smith
  • Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy
    Publication number: 20020177209
    Abstract: The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.
    Type: Application
    Filed: August 3, 2001
    Publication date: November 28, 2002
    Applicant: SmithKline Beecham plc
    Inventors: Colin Houston MacPhee, David Graham Tew, Christopher Donald Southan, Deirdre Mary Bernadette Hickey, Israel Simon Gloger, Geoffrey Mark Prouse Lawrence, Simon Quentyn John Rice
  • Novel compounds
    Publication number: 20020137907
    Abstract: Heparinase-like polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Heparinase-like polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: June 13, 2001
    Publication date: September 26, 2002
    Inventors: Christopher Donald Southan, Christopher Geoffrey Carson Larminie, Kim Rance, Philip David Hayes
  • Human RCE1
    Patent number: 6417332
    Abstract: The hRCE1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing hRCE1 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Grant
    Filed: June 26, 2000
    Date of Patent: July 9, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Kristine Kay Kikly, Anne M Knab, Christopher Donald Southan
  • Novel compounds
    Publication number: 20020001823
    Abstract: Hepatocyte Nuclear Factor 4&ggr; (HNF4g) polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Hepatocyte Nuclear Factor 4&ggr; (HNF4g) polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: December 7, 2000
    Publication date: January 3, 2002
    Inventors: Christopher Donald Southan, David Malcolm Duckworth, Stephen Anthony Hughes, William John Cairns
  • Novel compounds
    Publication number: 20010036648
    Abstract: MPROT45 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing MPROT45 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: December 15, 2000
    Publication date: November 1, 2001
    Inventors: Christopher Donald Southan, Stephen Anthony Hughes
  • MPROT12 polynucleotides and methods thereof
    Patent number: 6255468
    Abstract: MPROT12 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing MPROT12 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Grant
    Filed: May 5, 1999
    Date of Patent: July 3, 2001
    Assignee: SmithKline Beecham plc
    Inventors: Christopher Donald Southan, Joanne Rachel Evans
  • Compounds
    Patent number: 6180384
    Abstract: METPRO02 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing METPRO02 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: January 30, 2001
    Assignee: SmithKline Beecham plc
    Inventors: Christopher Donald Southan, Nicola Anne Burgess, Conrad Gerald Chapman
  • Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy
    Patent number: 6177257
    Abstract: The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: January 23, 2001
    Assignee: SmithKline Beechman
    Inventors: Colin Houston Macphee, David Graham Tew, Christopher Donald Southan, Deirdre Mary Bernadette Hickey, Israel Simon Gloger, Geoffrey Mark Prouse Lawrence, Simon Quentyn John Rice
  • Compounds
    Patent number: 6165771
    Abstract: The HE2NW40 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HE2NW40 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Grant
    Filed: June 1, 1998
    Date of Patent: December 26, 2000
    Assignee: SmithKline Beecham, P.L.C.
    Inventors: Nicola Anne Burgess, Helen Elizabeth Clinkenbeard, Christopher Donald Southan
  • Human RCE1
    Patent number: 6110717
    Abstract: The hRCE1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing hRCE1 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Grant
    Filed: February 12, 1998
    Date of Patent: August 29, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Kristine Kay Kikly, Anne M Knab, Christopher Donald Southan
  • Compounds
    Patent number: 6100059
    Abstract: HGBAB90 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HGBAB90 polypeptides and polynucleotides in the design of protocols for the treatment of pulmonary emphysema, arthritis, multiple sclerosis, periodontal disease, cystic fibrosis, respiratory disease, thrombosis, cancer, cachexia, angina, glaucoma, inflamatory disorders, osteoporosis, cardiovascular disorders such as hypertension, atherosclerotic disorders such as cardiac infarction, and stroke, asthma, psoriasis, chronic neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's, demyelinating diseases, AIDS immune deficiency, disorders of photoreceptor degeneration, and lens cataract formation, organ transplant rejection, cataracts, restenosis, muscular dystrophy, renal failure, cerebral vasospasm, pancreatitis, and diabetic nephropathy, among others, and diagnostic assays for such conditions.
    Type: Grant
    Filed: April 30, 1998
    Date of Patent: August 8, 2000
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Christopher Donald Southan, Helen Elizabeth Clinkenbeard, Nicola Anne Burgess
  • Compounds
    Patent number: 6090583
    Abstract: HTEGU07 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HTEGU07 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Grant
    Filed: May 20, 1998
    Date of Patent: July 18, 2000
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Helen Elizabeth Clinkenbeard, Christopher Donald Southan, Nicola Anne Burgess
  • Human AFC1
    Patent number: 6060277
    Abstract: The hAFC1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing hAFC1 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Grant
    Filed: February 12, 1998
    Date of Patent: May 9, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham PLC
    Inventors: Kristine Kay Kikly, Anne M Knab, Christopher Donald Southan