Abstract: A method of forming a shaped article wherein said article comprises at least two parts which are chemically bonded, the method comprising: assembling at least two non chemically bonded parts in a weld cavity of a tool to form an assembly of the at least two parts, wherein said weld cavity is adapted to receive the assembly of at least two parts in the form of the shaped article; sealing the weld cavity of the tool; melting the assembly of at least two parts to chemically bond the at least two parts together to form the shaped article, wherein the shape of the weld cavity is matched to the outer circumference of the assembly of parts such that thermal expansion forces the polymer parts against the weld cavity surface and the pressure leads to full surface bonds between all parts, and wherein the tool forming the weld cavity comprises two halves forming a piston which fits into the bore of a bolster component and the plane of the split line between the two piston halves is parallel to the axis of the bore such

Abstract: A method of forming a shaped foamed polymer article (16) and articles obtained from said method.

Abstract: A biocompatible surgical article is provided for cutting biological tissue or implantation in contact therewith. The surgical article has a composition of tungsten carbide-nickel with a percentage of additional metal carbides present. A typical composition in total weight percentages is WC 85 to 95%, Cr3C2, Mo2C, VC each alone or in combination being present from 0 to 2%, and Ni constituting the remainder. The composition is formed to have a mean grain size of between 200 and 800 nm with a particle dispersion index (PdI) corresponding to (the square of the standard deviation)/(mean grain size) of between 0 and 0.6, and in some embodiments between 0.02 and 0.2.

Abstract: A system for generating high-resolution video from low-resolution images is configured to access a first video stream and a second video stream capturing an environment. The first video stream is captured by a first video capture device. The second video stream is captured by a second video capture device. Image frames of the first video stream are temporally synchronized with corresponding image frames of the second video stream. The system is also configured to generate a composite video stream with a higher resolution than the first or second video streams. Each composite image frame of the composite video stream is generated using a respective image frame of the first video stream and a temporally synchronized corresponding image frame of the second video stream as input.

Abstract: A proactive execution system receives messages or other information from a plurality of different information channels. The proactive execution system automatically identifies messages that include a request for a user to perform a task. The proactive execution system then automatically generates a plan for executing that task and calls a plan execution system, with the plan, to perform the task. The proactive execution system receives a result from the plan execution system and generates an output indicative of that result, for access by the user.

Abstract: An assembly for a surgical arm includes a tool to position a prosthesis and an end effector. The tool has a tool shaft extending along a tool axis and a tool engagement surface. The end effector has a mount attachable to the surgical arm, a body portion extending from the mount, a distal end, and a guide portion is at the distal end of the body portion to receive the tool. The guide portion has a pair of arms, each arm extending to an arm end and the arm ends are spaced apart from one another to provide an opening between the arm ends. A channel is formed between the arms and extends along a guide axis. The arms define an arc-shaped guide engagement surface to enable contact with the tool engagement surface for facilitating alignment of the tool axis and the guide axis.

Abstract: An articulating joint comprising a multi-cluster joint where every consecutive pair of links is interfaced by a gimbal, which offers rotation about two orthogonal axes within the same plane. Thus, the articulating joint comprises an alternating sequence of links and gimbals. Furthermore, there may be multiple cables attached to one or more of the links. As these cables are selectively pulled and released, one can achieve any desired articulation of the articulating joint. There may be a transmission member extending through the links and gimbals, parallel to the central longitudinal axis of the joint in its nominal non-articulated condition. This transmission member may be either a tension member that is pulled on (e.g. a cable or flexible pull rod) and that loads the articulating joint in compression, or the transmission member may be a flexible push rod that loads the articulating joint in tension.

Abstract: A system for facilitating tone mapping is configurable to (i) generate an input image histogram based on one or more input images, the input image histogram comprising a plurality of bins, wherein each bin of the plurality of bins is associated with one or more pixel values and indicates a quantity of pixels that comprise the one or more pixel values; (ii) generate a target histogram based at least on the input image histogram; and (iii) generate an output image by using the target histogram to map pixel values of at least one of the one or more input images to corresponding pixel values in the output image.

Abstract: Method of making a shaped article (5) comprising at least two parts (10, 15) wherein the first part comprises at least one projection (20) and the second part comprises at least one recess (22) by preparing said first part and said second part in a moulding process and joining the prepared first and second part together by engaging the at least one projection with the at least one recess to form said shaped article.

Abstract: Systems, methods, and computer-readable media are provided for enabling mobile device-based item acquisition and tracking. One exemplary method performed on a mobile device comprises entering a wireless scan mode, detecting a signal from a tag associated with an item in a first area and in proximity to the tag, presenting information associated with the tag, and adding the information to a list. The method further comprises detecting a second tag in a second area, and sending the list to a second device. A second exemplary method performed by a processing terminal comprises receiving the list from a mobile device, entering a wireless scan mode, detecting a signal from a tag associated with an item in proximity to the tag, determining whether the item associated with the detected tag is present on the received list, and enabling the mobile device to complete a transaction to purchase the item.

Abstract: The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I): or pharmaceutically acceptable salts thereof wherein R, R1, R2, R3, R4, R5, R6, R7, and R8, are as defined herein. The disclosure also relates to methods of making and using compounds of Formula (I) or pharmaceutically acceptable salts thereof.

Abstract: A seating structure includes a base, a seat supported by the base, and a backrest supported by the base. The backrest includes a rear backrest section and a front backrest section coupled to the rear backrest section to define a gap therebetween. The gap extends around at least part of a perimeter of the backrest. The backrest further includes a fabric layer covering the front backrest section. A portion of the fabric layer is received in the gap.

Abstract: A system for facilitating motion compensation is configurable to access an affine transformation-compensated image. The affine transformation-compensated image is generated by applying affine transformation-based motion compensation to a previous image. The system is further configurable to generate a motion-compensated image by applying optical flow-based motion compensation to the affine transformation-compensated image. The optical flow-based motion compensation utilizes the affine transformation-compensated image and a current image as inputs.

Abstract: A system for generating a dark current residual image is configurable to generate a weighted average image by: (i) determining a region-based weight value for each pixel of an input image based upon a light level of a region in which the pixel lies; and (ii) combining the input image with a previous image using the region-based weight values for each pixel of the input image. The system is also configurable to generate a dark current residual image based upon the weighted average image.

Abstract: A system for facilitating dark current compensation by weighted filtering is configurable to (i) receive an input dark current image; (ii) generate a corrected dark current image at least by scaling pixel values of the input dark current image based upon ambient light conditions; and generate a weight map comprising a weight value for each pixel of the corrected dark current image. For each pixel of the corrected dark current image, the weight value of the weight map may be based upon a light level of the pixel of the corrected dark current image. The system is also configurable to generate an output image by utilizing the weight map to filter an input image.

Abstract: A system for modifying a dark current image is configurable to receive an input image depicting a dark current state for one or more pixels of the input image, The dark current state for one or more pixels of the input image comprises one of: a faulty state or a non-faulty state. The system is configurable to partition the input image into a plurality of partitions and generate an updated input image by imposing at least one quantity constraint or at least one severity constraint to the plurality of partitions in association with at least one type of dark current state.

Abstract: Systems and methods disclosed herein may include a parallel-processing graph-database solution for protein-sequence analytics to determine a viable therapeutic for a given condition, and may include: determining a protein sequence for the given condition; using sequence database to compare a query sequence of the sequence of the given condition with sequences of other known proteins in the sequence database using the sequence database to determine a similarity of the query sequence with sequences of the other known proteins in the sequence database based on the comparison; and querying a graph database based on the similarity of sequences to identify potential therapeutics that could be have an inhibitory effect on the given condition.

Abstract: A system for low compute high-resolution depth map generation using low-resolution cameras is configured to obtain a stereo pair of images and generate a depth map by performing stereo matching on the stereo pair of images. The system is also configured to obtain a first image comprising first texture information for the environment that has a first image resolution that is higher than an image resolution of images of the stereo pair of images. The system is further configured to generate a reprojected first image by reprojecting the first image to correspond to an image capture perspective associated with the depth map. The reprojection of the first image is based on depth information from the depth map and includes reprojected first texture information for the environment. The system is also configured to generate an upsampled depth map based on the depth map.

Abstract: An optical coherence tomography (OCT) system comprises: an imaging catheter; a calibration phantom removably arranged at least partially surrounding the distal end of the catheter; and a processor configured to control the catheter to acquire OCT images. The phantom has known dimensions and specific optical properties which provide non-changing calibration fiducials that span the imaging range of the system. The phantom is imaged by the catheter upon first connection to the system. The processor calculates a thickness of the phantom in the OCT image, and preforms z-offset calibration by setting the position of a phantom surface in the OCT image to a known nominal value. The known nominal value is related to one or more of the known thickness of the phantom or a diameter of the catheter sheath or a nominal angle of the light beam or the imaging range of the system.

Abstract: A hydraulic control system for use with a work machine. The work machine has a platform which supports an operator. When the operator is not on the platform, the platform moves into a first position, causing a signal generator to send a signal to a controller. The controller is configured to limit the hydraulic flow to the ground drive motor when the platform is in the first position. The controller may directly reduce operation of the engine, or may adjust a valve which diverts a portion of hydraulic flow. The limitation may be overridden when desired by the operator.