Patents by Inventor Christopher E. Rudd

Christopher E. Rudd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Signal transduction via CD28
    Patent number: 5525503
    Abstract: Disclosed are compositions and methods of blocking T cell signal transduction by introducing into a T cell a peptide comprising a PI 3-kinase-binding-sequence which decreases the association of PI 3-kinase with CD28. Also disclosed are compositions and methods of amplifying T cell activation by introducing into a T cell, a plurality of modified T cell surface proteins, the cytoplasmic tail of which comprises a plurality of copies of a PI 3-kinase-binding-sequence.
    Type: Grant
    Filed: September 28, 1993
    Date of Patent: June 11, 1996
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Christopher E. Rudd, Prasad Kanteti