Patents by Inventor Christopher Earle Newall

Christopher Earle Newall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Steroidal anaesthetics of the pregnane and 19-norpregnane series
    Patent number: 3983111
    Abstract: Steroid anaesthetics of the pregnane and 19-norpregnane series are described, the steroids having a 3.alpha.-hydroxy group, a 17.alpha.-hydrogen atom, a 20-oxo group and at the 21-position a cyano, azido or basic amino group.
    Type: Grant
    Filed: September 23, 1974
    Date of Patent: September 28, 1976
    Assignee: Glaxo Laboratories Limited
    Inventors: Gordon Hanley Phillipps, Robin Lawrence, Christopher Earle Newall
  • 20.beta.,21-Epoxy-3.alpha.-hydroxy-5.alpha.-pregnanes and derivatives thereof
    Patent number: 3969345
    Abstract: The invention provides 3.alpha.-oxygenated pregnane 21-ethers possessing a hydroxy group in the 3.alpha.-position; a hydrogen atom or a methyl group at the 10-position; a hydrogen atom in the 17.alpha.-position; a keto group in the 20-position; and an etherified hydroxyl group in the 21-position.
    Type: Grant
    Filed: February 20, 1975
    Date of Patent: July 13, 1976
    Assignee: Glaxo Laboratories Limited
    Inventors: Gordon Hanley Phillipps, Christopher Earle Newall
  • Anaesthetic steroids of the pregnane and 19-norpregnane series having a sulfur-containing group at the 21-position
    Patent number: 3959260
    Abstract: Steroid anaesthetics of the pregnane and 19-norpregnane series are described, the compounds possessing a 3.alpha.-hydroxy group, a 17.alpha.-hydrogen atom, a 20-oxo group and at the 21-position the residue of a sulphur nucleophile or a sulphone or sulphoxide grouping.
    Type: Grant
    Filed: July 16, 1974
    Date of Patent: May 25, 1976
    Assignee: Glaxo Laboratories Limited
    Inventors: Gordon Hanley Phillipps, Robin Lawrence, Christopher Earle Newall, Michael Wright
  • Anaesthetic steroids of the androstance and pregnane series
    Patent number: 3953429
    Abstract: Steroids of the androstane and pregnane series possessing a 2.alpha.-hydrogen or halogen or an alkyl group; a 3.alpha.-hydroxy or acyloxy group, a 3.beta.-hydrogen or alkyl group; an 11.beta.-hydrogen or hydroxy group or an epoxy group linked also to the 9-position; an 11.alpha.-hydrogen or alkyl or allyl group; or an 11-oxo group; a 16 hydrogen or halogen or a methyl or dimethyl group; a 20-oxo or ethylenedioxy group; and a 20-methyl or alkoxy group. The compounds may be unsaturated at the 1(2), 8(9) or 9(11) positions.The compounds possess anaesthetic properties.
    Type: Grant
    Filed: February 19, 1974
    Date of Patent: April 27, 1976
    Assignee: Glaxo Laboratories Limited
    Inventors: Martin Christopher Cook, Robin Lawrence, Gordon Hanley Phillipps, Anne Christine Hunter, Christopher Earle Newall, Leslie Stephenson, Niall Galbraith Weir
  • Anaesthetic composition containing a steroid of the 5.alpha.-pregnane series and method of using same
    Patent number: 3952031
    Abstract: This invention relates to steroids of the pregnane and 19-norpregnane series having anaesthetic properties and compositions containing them. More particularly the present invention relates to such steroids having a variety of substituents in the 2.beta.-position, a 3.alpha.-hydroxy group and a 5.alpha.-hydrogen atom and esters and 20-ketals thereof. At the 11-position of such steroids is preferably either two hydrogen atoms or an oxo group. The compounds according to the invention may conveniently be prepared by reaction of an appropriate 2.alpha.,3.alpha.-epoxy-pregnane or 19-norpregnane with a reagent which introduces the desired 2.beta.-substituent and various modifications of the compound produced are described to produce compounds within the scope of the invention.
    Type: Grant
    Filed: December 13, 1974
    Date of Patent: April 20, 1976
    Assignee: Glaxo Laboratories Limited
    Inventors: Gordon Hanley Phillipps, Christopher Earle Newall, Barry Edward Ayres
  • Chemical compounds
    Patent number: 3943124
    Abstract: Steroids of the androstane series having a 3.alpha.-hydroxy group, a 3.beta.-hydrogen or methyl group; a 10-hydrogen atom or methyl group, an 11-oxo group or two hydrogen atoms at the 11-position, a 17.alpha.-hydrogen atom, and a group at the 17.beta.-position which is esterified carboxyl group, an N-mono or di-substituted carbamoyl group, a cyano group, a formyl group or an acetalised formyl group; and the 3.alpha.-esters thereof.The steroids possess anaesthetic properties.
    Type: Grant
    Filed: June 20, 1974
    Date of Patent: March 9, 1976
    Inventors: Gordon Hanley Phillipps, Christopher Earle Newall