Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: An axial flux machine is described. The machine has a stator comprising a stator housing enclosing a plurality of stator bars disposed circumferentially at intervals around an axis of the machine, and a rotor comprising a set of permanent magnets and mounted for rotation about the axis of the machine. The rotor is spaced apart from the stator along the axis of the machine to define a gap between the stator and rotor and in which magnetic flux in the machine is generally in an axial direction. The machine also comprises a hub assembly comprising a rotating hub and a mount separated by a bearing to permit the hub to rotate relative to the mount, the rotating hub comprising a hub flange and the mount comprising a mount flange, each of the flanges being spaced axially apart from one another. The machine further comprises a bulkhead for mounting the hub assembly and stator, wherein the bulkhead is mounted to the mount flange of the hub assembly and the stator housing is mounted to the bulkhead.

Abstract: An axial flux machine is described. The machine has a stator comprising a stator housing enclosing a plurality of stator bars disposed circumferentially at intervals around an axis of the machine, and a rotor comprising a set of permanent magnets and mounted for rotation about the axis of the machine. The rotor is spaced apart from the stator along the axis of the machine to define a gap between the stator and rotor and in which magnetic flux in the machine is generally in an axial direction. The machine also comprises a hub assembly comprising a rotating hub and a mount separated by a bearing to permit the hub to rotate relative to the mount, the rotating hub comprising a hub flange and the mount comprising a mount flange, each of the flanges being spaced axially apart from one another. The machine further comprises a bulkhead for mounting the hub assembly and stator, wherein the bulkhead is mounted to the mount flange of the hub assembly and the stator housing is mounted to the bulkhead.

Abstract: A system includes a turbomachine. The turbomachine includes at least one rotor disk. The system also includes a rotor disk heating system configured to resistively heat at least a portion of the at least one rotor disk via an electrical current or voltage applied to the portion of the at least one rotor disk.

Abstract: A system, including a first turbomachine rotor disk, a first annular protrusion with a first spline coupled to the first turbomachine rotor disk, a second turbomachine rotor disk, and a second annular protrusion with a second spline coupled to the second turbomachine rotor disk, wherein the first and second splines are coupled to one another.

Abstract: A method, apparatus, system, article of manufacture, and data structure provide the ability to debug a map-reduce application on a cluster. A cluster of two or more computers is defined by installing a map-reduce framework (that includes an integrated development environment [IDE]) onto each computer. The cluster is formatted by identifying and establishing communication between each computer so that the cluster functions as a unit. Data is placed into the cluster. A function to be executed by the framework on the cluster is obtained, debugged, and executed directly on the cluster using the IDE and the data in the cluster.

Abstract: A system includes a turbomachine. The turbomachine includes at least one rotor disk. The system also includes a rotor disk heating system configured to resistively heat at least a portion of the at least one rotor disk via an electrical current or voltage applied to the portion of the at least one rotor disk.

Abstract: Various embodiments include a turbine apparatus and a related monitoring system. In various embodiments, an apparatus includes a turbine rotor having: a rotor body; sets of rotor blades axially dispersed along the rotor body and extending radially from the rotor body; a spacer region axially separating two adjacent sets of the sets of rotor blades along the rotor body; a conductive element located within the spacer region for initiating an electrical current; and a module electrically connected with the conductive element for receiving the electrical current from the conductive element and powering at least one monitoring device onboard the rotor body.

Abstract: Systems and methods for controlling a gas turbine are disclosed. The gas turbine can include a compressor oversized in airflow capacity and one or variable blade rows to control the airflow into the compressor. The position of the variable blade rows can be controlled according to a nominal variable blade row schedule that is defined to throttle down the variable blade rows to provide nominal flow into the compressor. The positions of the variable blade rows can be adjusted from the nominal positions set forth in the variable blade row schedule pursuant to a request to operate the gas turbine system in either a controlled output mode or in a frequency compensation mode.

Abstract: Systems and methods for controlling a gas turbine are disclosed. The gas turbine can include a compressor oversized in airflow capacity and one or variable blade rows to control the airflow into the compressor. The position of the variable blade rows can be controlled according to a nominal variable blade row schedule that is defined to throttle down the variable blade rows to provide nominal flow into the compressor. The positions of the variable blade rows can be adjusted from the nominal positions set forth in the variable blade row schedule pursuant to a request to operate the gas turbine system in either a controlled output mode or in a frequency compensation mode.

Abstract: A rotor assembly is disclosed. The rotor assembly may include a first rotor disk defining a first axially extending slot and a second rotor disk defining a second axially extending slot. Additionally, the rotor assembly may include a pin extending lengthwise between the first and second rotor disks. The pin may include a first end terminating within the first axially extending slot and a second end terminating within the second axially extending slot.

Abstract: A method, apparatus, system, article of manufacture, and data structure provide the ability to perform a sorted map-reduce job on a cluster. A cluster of two or more computers is defined by installing a map-reduce framework onto each computer and formatting the cluster by identifying the cluster computers, establishing communication between them, and enabling the cluster to function as a unit. Data is placed into the cluster where it is distributed so that each computer contains a portion of the data. A first map function is performed where each computer sorts their respective data and creates an abstraction that is a representation of the data. The abstractions are exchanged and merged to create complete abstraction. A second map function searches the complete abstraction to redistribute and exchange the data across the computers in the cluster. A reduce function is performed in parallel to produce a result.

Abstract: A method, apparatus, system, article of manufacture, and data structure provide the ability to debug a map-reduce application on a cluster. A cluster of two or more computers is defined by installing a map-reduce framework (that includes an integrated development environment [IDE]) onto each computer. The cluster is formatted by identifying and establishing communication between each computer so that the cluster functions as a unit. Data is placed into the cluster. A function to be executed by the framework on the cluster is obtained, debugged, and executed directly on the cluster using the IDE and the data in the cluster.

Abstract: A method, apparatus, system, article of manufacture, and data structure provide the ability to perform a sorted map-reduce job on a cluster. A cluster of two or more computers is defined by installing a map-reduce framework onto each computer and formatting the cluster by identifying the cluster computers, establishing communication between them, and enabling the cluster to function as a unit. Data is placed into the cluster where it is distributed so that each computer contains a portion of the data. A first map function is performed where each computer sorts their respective data and creates an abstraction that is a representation of the data. The abstractions are exchanged and merged to create complete abstraction. A second map function searches the complete abstraction to redistribute and exchange the data across the computers in the cluster. A reduce function is performed in parallel to produce a result.