Abstract: The present application provides a personal hand-held monitor for the measurement of a subject's blood pressure and, optionally, one or more vital signs, and includes a housing located on a personal hand-held computing device or a hand-held component of a computing system; a blood flow occlusion means located in the housing; a pressure sensor adapted to provide an electrical signal indicative of pressure applied; a means for detecting the flow of blood in the body part of the subject when pressure is applied; and means for receiving electrical signals from the pressure sensor and the blood flow detecting means and for transmitting electrical signals indicative of the pressure and blood flow to the processor, which provides at least a measurement of the blood pressure of a subject. The processor is further adapted to carry out a process to measure a diastolic blood pressure value and a systolic blood pressure value.

Abstract: The present invention provides a personal hand-held monitor comprising a signal acquisition device for acquiring signals which can be used to derive a measurement of a parameter related to the health of the user, the signal acquisition device being integrated with a personal hand-held computing device. The present invention also provides a signal acquisition device adapted to be integrated with a personal hand-held computing device to produce a personal hand-held monitor as defined above.

Abstract: A device is disclosed for measuring blood pressure comprising a signal acquisition component comprising a flexible and essentially incompressible gel or resin, a surface of which is adapted in use to contact a body part; a pressure sensor embedded in the gel or resin, one or more photoemitters for emitting light into the body part when the body part is in contact with the surface of the gel or resin, one or more photodetectors for detecting light scattered by or transmitted through the body part; a processing means which is programmed for analysing the signals from the pressure sensor and the photodetector(s) to provide a measurement of blood pressure in the body part; and a mechanism for applying force, which is adapted to apply varied force to the body part in a direction towards the surface of the gel or resin.

Abstract: The present invention provides a personal hand-held monitor comprising a signal acquisition device for acquiring signals which can be used to derive a measurement of a parameter related to the health of the user, the signal acquisition device being integrated with a personal hand-held computing device. The present invention also provides a signal acquisition device adapted to be integrated with a personal hand-held computing device to produce a personal hand-held monitor as defined above.

Abstract: The present invention provides a PHHM for the measurement of a subject's BP and, optionally, one or more other vital signs, comprising a housing located on a PHHCD or a hand-held component of a computing system; a blood flow occlusion means located in the housing such that, when the housing is located on the PHHCD or the hand-held component, an open surface of the blood flow occlusion means is available to be pressed against a body part of the subject or to have a body part of the subject pressed against it; a pressure sensor adapted to provide an electrical signal indicative of the pressure applied to or by the open surface; a means for detecting the flow of blood in the body part of the subject when pressure is applied to or by the open surface; and means for receiving electrical signals from the pressure sensor and the blood flow detecting means and for transmitting electrical signals indicative of the pressure and blood flow to the processor of the PHHCD or the computing system, wherein the processor of t

Abstract: The present application describes a PHHM of the type described in WO 2013/002165, WO 2014/125431 and International Patent Application No. PCT/EP2015/079888 with improved aspects to find indicators of health, and other improvements that facilitate its construction and calibration.

Abstract: The invention disclosed herein relates to improvements in the collection personal health data. It further relates to a Personal Health Monitor (PHM), which may be a Personal Hand Held Monitor (PHHM), that incorporates a Signal Acquisition Device (SAD) and a processor with its attendant screen and other peripherals. The SAD is adapted to acquire signals which can be used to derive one or more measurements of parameters related to the health of a user. The computing and other facilities of the PHM with which the SAD is integrated are adapted to control and analyse signals received from the SAD. The personal health data collected by the SAD may include data related to one or more of blood pressure, pulse rate, blood oxygen level (SpO2), body temperature, respiration rate, ECG, cardiac output, heart function timing, arterial stiffness, tissue stiffness, hydration, blood viscosity, blood pressure variability, the concentration of constituents of the blood such as glucose or alcohol and the identity of the user.

Abstract: The present invention provides a PHHM for the measurement of a subject's BP and, optionally, one or more other vital signs, comprising a housing located on a PHHCD or a hand-held component of a computing system; a blood flow occlusion means located in the housing such that, when the housing is located on the PHHCD or the hand-held component, an open surface of the blood flow occlusion means is available to be pressed against a body part of the subject or to have a body part of the subject pressed against it; a pressure sensor adapted to provide an electrical signal indicative of the pressure applied to or by the open surface; a means for detecting the flow of blood in the body part of the subject when pressure is applied to or by the open surface; and means for receiving electrical signals from the pressure sensor and the blood flow detecting means and for transmitting electrical signals indicative of the pressure and blood flow to the processor of the PHHCD or the computing system, wherein the processor of t

Abstract: The present application describes a Personal Hand-Held Monitor (PHHM) of the type described in WO 2013/002165, WO 2014/125431, and International Patent Application No. PCT/EP2015/079888, with improved aspects to find indicators of health, and other improvements that facilitate its construction and calibration.

Abstract: The present application provides a personal hand-held monitor for the measurement of a subject's blood pressure and, optionally, one or more other vital signs, comprising a housing located on a personal hand-held computing device or a hand-held component of a computing system; a blood flow occlusion means located in the housing; a pressure sensor adapted to provide an electrical signal indicative of the pressure applied; a means for detecting the flow of blood in the body part of the subject when pressure is applied; and means for receiving electrical signals from the pressure sensor and the blood flow detecting means and for transmitting electrical signals indicative of the pressure and blood flow to the processor of the personal hand-held computing device or the computing system, wherein the processor of the personal hand-held computing device or computing system provide at least a measurement of the blood pressure of a subject.

Abstract: A personal hand-held monitor (PHHM) comprising a signal acquisition device for acquiring signals which can be used to derive a measurement of a parameter related to the health of the user, wherein the signal acquisition device comprises a blood photosensor having one or more photo-emitters for transmitting light to a body part of a user, one or more photo-detectors for detecting light transmitted through or scattered by the body part and two or more optical cells, at least one of which contains an analyte to be detected or which mimics the absorption spectrum of the analyte to be detected, through which the light that has been or will be transmitted through or scattered by the body part passes before it reaches the or each photo-detector, wherein the processor of the PHHM is adapted to process the signals received from the or each photo-detector to calculate the difference in intensity of light which has passed through the or each analyte cell and light which has passed through the or each non-analyte cell an

Abstract: The present invention provides a personal hand-held monitor comprising a signal acquisition device for acquiring signals which can be used to derive a measurement of a parameter related to the health of the user, the signal acquisition device being integrated with a personal hand-held computing device. The present invention also provides a signal acquisition device adapted to be integrated with a personal hand-held computing device to produce a personal hand-held monitor as defined above.

Abstract: The present invention provides a personal hand-held monitor comprising a signal acquisition device for acquiring signals which can be used to derive a measurement of a parameter related to the health of the user, the signal acquisition device being integrated with a personal hand-held computing device. The present invention also provides a signal acquisition device adapted to be integrated with a personal hand-held computing device to produce a personal hand-held monitor as defined above.

Abstract: The invention disclosed herein relates to improvements in the collection personal health data. It further relates to a Personal Health Monitor (PHM), which may be a Personal Hand Held Monitor (PHHM), that incorporates a Signal Acquisition Device (SAD) and a processor with its attendant screen and other peripherals. The SAD is adapted to acquire signals which can be used to derive one or more measurements of parameters related to the health of a user. The computing and other facilities of the PHM with which the SAD is integrated are adapted to control and analyse signals received from the SAD. The personal health data collected by the SAD may include data related to one or more of blood pressure, pulse rate, blood oxygen level (SpO2), body temperature, respiration rate, ECG, cardiac output, heart function timing, arterial stiffness, tissue stiffness, hydration, the concentration of constituents of the blood such as glucose or alcohol and the identity of the user.

Abstract: The invention relates to methods and kits for DNA The method comprises a) contacting the sample with a plurality of metal nanoparticles functionalised with one or more RNA probes; b) forming a heteroduplex between the target DNA and RNA probe on an RNA-functionalised metal nanoparticle; c) contacting the heteroduplex of target DNA and RNA probe on the RNA-functionalised metal nanoparticle with an enzyme that cleaves RNA in a DNA-RNA heteroduplex thereby releasing the target DNA; d) repeating steps (b) and (c) until all, or substantially all, of the RNA probes on the plurality of RNA-functionalised metal nanoparticles have been cleaved from the metal nanoparticles; and e) aggregating the metal nanoparticles from which all, or substantially all, of the RNA probes have been cleaved, thereby indicating the presence of the target DNA.

Abstract: A modular fencing storage and handling apparatus includes at least one interchangeable automated reel cradle module having a cradle for the storage and handling of a fence wire reel, a powered driving mechanism to control the automated winding of a fence wire onto the fence wire reel and a layering device, which allows the fence wire to be layered evenly across the fence wire reel as it is being fed onto the fence wire reel.

Abstract: The present invention is related to methods and kits for the detection of deoxyribonucleic acid (DNA), in particular pathogenic microbial DNA, which provide more simple and sensitive detection of DNA compared to similar methods and kits known in the art.

Abstract: The present invention provides a personal hand-held monitor comprising a signal acquisition device for acquiring signals which can be used to derive a measurement of a parameter related to the health of the user, the signal acquisition device being integrated with a personal hand-held computing device. The present invention also provides a signal acquisition device adapted to be integrated with a personal hand-held computing device to produce a personal hand-held monitor as defined above.

Abstract: A personal hand-held monitor (PHHM) comprising a signal acquisition device for acquiring signals which can be used to derive a measurement of a parameter related to the health of the user, wherein the signal acquisition device comprises a blood photosensor having one or more photo-emitters for transmitting light to a body part of a user, one or more photo-detectors for detecting light transmitted through or scattered by the body part and two or more optical cells, at least one of which contains an analyte to be detected or which mimics the absorption spectrum of the analyte to be detected, through which the light that has been or will be transmitted through or scattered by the body part passes before it reaches the or each photo-detector, wherein the processor of the PHHM is adapted to process the signals received from the or each photo-detector to calculate the difference in intensity of light which has passed through the or each analyte cell and light which has passed through the or each non-analyte cell an

Abstract: The present invention is related to methods and kits for the detection of deoxyribonucleic acid (DNA), in particular pathogenic microbial DNA, which provide more simple and sensitive detection of DNA compared to similar methods and kits known in the art.