Patents by Inventor Christopher Emil Whitehead

Christopher Emil Whitehead has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small molecule inhibitors of EGFR and PI3K
    Patent number: 11607414
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases.
    Type: Grant
    Filed: October 7, 2020
    Date of Patent: March 21, 2023
    Assignee: The Regents of the University of Michigan
    Inventors: Christopher Emil Whitehead, Judith S. Leopold
  • SMALL MOLECULE INHIBITORS OF EGFR AND PI3K
    Publication number: 20210023085
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases.
    Type: Application
    Filed: October 7, 2020
    Publication date: January 28, 2021
    Inventors: Christopher Emil Whitehead, Judith S. Leopold
  • Small molecule inhibitors of EGFR and PI3K
    Patent number: 10842791
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: November 24, 2020
    Assignee: The Regents of the University of Michigan
    Inventors: Christopher Emil Whitehead, Judith S. Leopold
  • SMALL MOLECULE DUAL INHIBITORS OF EGFR/PI3K AND USES THEREOF
    Publication number: 20200078360
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to anew class of small-molecules having a quinazoline structure which function as dual inhibitors EGFR and PI3K, and their use as therapeutics for the treatment of cancer (e.g., cancers associated with mutated KRAS and BRAF) (e.g., in combination with MAPK pathway inhibitors (e.g., BRAF inhibitors, MEK inhibitors, ERK inhibitors).
    Type: Application
    Filed: November 3, 2017
    Publication date: March 12, 2020
    Inventors: Christopher Emil WHITEHEAD, Elizabeth ZIEMKE, Judith SEBOLT-LEOPOLD
  • SMALL MOLECULE INHIBITORS OF EGFR AND PI3K
    Publication number: 20190167686
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases.
    Type: Application
    Filed: December 3, 2018
    Publication date: June 6, 2019
    Inventors: Christopher Emil Whitehead, Judith S. Leopold
  • Small molecule inhibitors of EGFR and PI3K
    Patent number: 10206924
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: February 19, 2019
    Assignee: The Regents of the University of Michigan
    Inventors: Christopher Emil Whitehead, Judith S. Leopold
  • SMALL MOLECULE INHIBITORS OF EGFR AND PI3K
    Publication number: 20170360788
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases.
    Type: Application
    Filed: December 15, 2015
    Publication date: December 21, 2017
    Inventors: Christopher Emil Whitehead, Judith S. Leopold
  • 5-substituted-4-[(substituted phenyl) amino]-2-pyridone derivatives
    Patent number: 7273877
    Abstract: The present invention relates to 5-substituted-4-(substituted)phenylamino-2-pyridone derivatives, pharmaceutical compositions and methods of use thereof.
    Type: Grant
    Filed: June 24, 2004
    Date of Patent: September 25, 2007
    Assignee: Warner-Lambert Company, LLC
    Inventors: Shannon Leigh Black, Michael David Kaufman, Daniel Fred Ortwine, Mark Stephen Plummer, John Quin, III, Gordon William Rewcastle, Aurash B. Shahripour, Julie Ann Spicer, Christopher Emil Whitehead