Patents by Inventor CHRISTOPHER ESPELIN

CHRISTOPHER ESPELIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination Therapies for Treating Her2-Positive Cancers that are Resistant to Her2-Targeted Therapies
    Publication number: 20170080087
    Abstract: Methods for treating cancer patients (e.g., cancer patients resistant or intolerant to pertuzumab and ado-trastuzumab emtansine) having HER2-positive tumors are disclosed. The methods comprise administering to a patient a therapeutically effective amount of a combination of a doxorubicin-loaded immunoliposome with a targeting moiety that is an anti-HER2 antibody that is not an inhibitor of HER2 signaling and an anti-cancer therapeutic comprising a doxorubicin-free anti-cancer therapeutic comprising a different anti-HER2 antibody.
    Type: Application
    Filed: December 5, 2016
    Publication date: March 23, 2017
    Applicant: MERRIMACK PHARMACEUTICALS, INC.
    Inventors: CHRISTOPHER ESPELIN, ELENA GERETTI, VICTOR MOYO, JOSEPH G. REYNOLDS, THOMAS WICKHAM, BART S. HENDRIKS