Patents by Inventor Christopher F. J. Barnard

Christopher F. J. Barnard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Platinum complexes
    Patent number: 5519155
    Abstract: Pt(IV) complexes of formula I, ##STR1## where X is halide, pseudohalide or OH,R.sup.1 and R.sup.2 are H, C.sub.1 to C.sub.6 alkyl, cycloalkyl, aryl or R.sup.1 NH.sub.2 is a heterocyclic hydrogen donor, and may be the same or different,R.sup.3 and R.sup.4 are H, C.sub.1 to C.sub.5 alkyl, cycloalkyl or aryl and may be the same or different, andR.sup.5 is H, Me or Et,have activity in vitro and in vivo against cancer cells.
    Type: Grant
    Filed: April 25, 1995
    Date of Patent: May 21, 1996
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Christopher F. J. Barnard, Gerald E. Bossard
  • Trans-Pt (IV) compounds
    Patent number: 5194645
    Abstract: Trans-Pt(IV) compounds of general formula[PtX.sub.2 Y.sub.2 L.sup.1 L.sup.2)]where X is halogen, Y is halogen, hydroxyl or carboxylate and each L is an amine ligand, providing L.sup.1 and L.sup.2 are not both NH.sub.3 are surprisingly active against cancer cells, in contrast to expectations that all trans-Pt compounds are inactive.
    Type: Grant
    Filed: March 9, 1992
    Date of Patent: March 16, 1993
    Assignee: Johnson Matthey Public Limited Company
    Inventor: Christopher F. J. Barnard
  • Anti-tumor compounds of platinum
    Patent number: 4687780
    Abstract: A coordination compound of platinum suitable for the treatment of cancer and especially for oral administration has the general formula ##STR1## in which A is NH.sub.3 or cycloalkylamine, B is cycloalkylamine, and the R moieties are the same or different selected from H, lower alkyl etc. or form a cycloalkyl or cycloalkenyl group with the C atom.
    Type: Grant
    Filed: June 18, 1985
    Date of Patent: August 18, 1987
    Assignee: Johnson Matthey PLC
    Inventor: Christopher F. J. Barnard