Abstract: Coating compositions comprising a polymer binder and a sphere selected from porous metal oxide spheres formed from metal oxide particles and having, e.g., an average porosity of from 0.10 to 0.90; polymer spheres formed from a multimodal distribution of polymer particles; or mixtures thereof, are described herein. The sphere enhances the reflective characteristics of the coating compositions with respect to electromagnetic radiation. In particular, the coating compositions when dried, can exhibit UV reflectance, visible light reflectance, IR reflectance, or a combination thereof.

Abstract: Coating compositions comprising a polymer binder and hybrid metal oxide particles are described herein.

Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a 6,5-heterocyclic structure (e.g., compounds having a imidazopyridine, imidazopyrimidine, imidazopyrazine, imidazopyridazine, imidazotriazine, benzoimidazole, benzotriazole, benzoisoxazole, purine, indazole, triazolotriazine, triazolopyridazine, triazolopyrimidine, triazolopyrazine, triazolotetrazine, triazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolopyridazine, pyrazolotriazine, pyrazolopyridine, isoxazolopyrazine, isoxazolopyrimidine, isoxazolopyrdiazine, isoxazolotriazine, or isoxalopyridine structure) which function as inhibitors of DYRK1A, DYRK1B, and Clk-1, and their use as therapeutics for the treatment of Alzheimer's disease, Down syndrome, diabetes, glioblastoma, autoimmune diseases, cancer (e.g., glioblastoma, prostate cancer), inflammatory disorders (e.g., airway inflammation), and other diseases.

Abstract: A delta between a first version of a software application and a second version of the software application is determined, the delta including a plurality of delta binary values that identify a difference between the first version of the software application and the second version of the software application. A first plurality of qubits are encoded with a primary software application version that is one of the first version of the software application or the second version of the software application. Qubit metadata that refers to a second plurality of qubits is generated based on the delta, the second plurality of qubits including at least some of the first plurality of qubits The second version of the software application is generated from the first plurality of qubits, the second plurality of qubits and the qubit metadata.

Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a 6,5-heterocyclic structure (e.g., compounds having a imidazopyridine, imidazopyrimidine, imidazopyrazine, imidazopyridazine, imidazotriazine, benzoimidazole, benzotriazole, benzoisoxazole, purine, indazole, triazolotriazine, triazolopyridazine, triazolopyrimidine, triazolopyrazine, triazolotetrazine, triazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolopyridazine, pyrazolotriazine, pyrazolopyridine, isoxazolopyrazine, isoxazolopyrimidine, isoxazolopyrdiazine, isoxazolotriazine, or isoxalopyridine structure) which function as inhibitors of DYRK1A, DYRK1B, and Clk-1, and their use as therapeutics for the treatment of Alzheimer's disease, Down syndrome, diabetes, glioblastoma, autoimmune diseases, cancer (e.g., glioblastoma, prostate cancer), inflammatory disorders (e.g., airway inflammation), and other diseases.

Abstract: A continuous optimizer detects a code promotion of a candidate release of an application. In response to the code promotion, the continuous optimizer instantiates a JVM and profiles the application to obtain a JVM profile. The continuous optimizer benchmarks the candidate release against the JVM and JVM profile. The continuous optimizer further compares the benchmark results with previous benchmark results. Based upon the comparison and a set of rules, the continuous optimizer causes the candidate release to be promoted.

Abstract: A continuous optimizer detects a code promotion of a candidate release of an application. In response to the code promotion, the continuous optimizer instantiates a JVM and profiles the application to obtain a JVM profile. The continuous optimizer benchmarks the candidate release against the JVM and JVM profile. The continuous optimizer further compares the benchmark results with previous benchmark results. Based upon the comparison and a set of rules, the continuous optimizer causes the candidate release to be promoted.

Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a 6,5-heterocyclic structure (e.g., compounds having a imidazopyridine, imidazopyrimidine, imidazopyrazine, imidazopyridazine, imidazotriazine, benzoimidazole, benzotriazole, benzoisoxazole, purine, indazole, triazolotriazine, triazolopyridazine, triazolopyrimidine, triazolopyrazine, triazolotetrazine, triazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolopyridazine, pyrazolotriazine, pyrazolopyridine, isoxazolopyrazine, isoxazolopyrimidine, isoxazolopyrdiazine, isoxazolotriazine, or isoxalopyridine structure) which function as inhibitors of DYRK1A, DYRK1B, and Clk-1, and their use as therapeutics for the treatment of Alzheimer's disease, Down syndrome, diabetes, glioblastoma, autoimmune diseases, cancer (e.g., glioblastoma, prostate cancer), inflammatory disorders (e.g., airway inflammation), and other diseases.

Abstract: Centralized monitoring of plural file systems that operate within or in association with an enterprise computing environment is provided. Each of the plural file systems are provided with a security policy, wherein the security policy defines one or more file system access activities to be monitored at the file system. Each file system is instrumented with a software agent that intercepts the relevant file system access activity. A centralized collector component is operative to receive from each of the plural file systems audit trail data, wherein the audit trail data is data that has been generated locally as file system access activity is intercepted at the file system by the local software agent in accordance with the applicable security policy. The collector applies the security policy against the audit trail data received from at least one of the plural file systems and, in response thereto, takes a given action.

Abstract: An image quality control system is disclosed. The example system includes an artificial intelligence modeler to process image data and metadata from patient data to generate first feature(s) from the image data and to parse the metadata to identify study information. The example system includes a computer vision processor to identify second feature(s) in the image data. The example system includes a results evaluator to compare the first feature(s) and second feature(s) to generate a comparison and to evaluate the comparison, first feature(s), and second feature(s) with respect to the study information to generate an evaluation. The example system includes a quality controller to compare the evaluation to quality criterion(-ia) to produce an approval or rejection of the patient data, the approval to trigger release of the patient data and the rejection to deny release of the patient data.

Abstract: A system of computers in network communication where: (i) an end user's computer accesses an instantiation of a virtual machine using remote console software; (ii) the access to the VM is performed through a proxy server; and (iii) by using the proxy server, when the VM instantiation is moved from one physical host computer to another physical host computer, there is no substantial interruption in the access of the VM by the end user through the remote console software.

Abstract: A system of computers in network communication where: (i) an end user's computer accesses an instantiation of a virtual machine using remote console software; (ii) the access to the VM is performed through a proxy server; and (iii) by using the proxy server, when the VM instantiation is moved from one physical host computer to another physical host computer, there is no substantial interruption in the access of the VM by the end user through the remote console software.

Abstract: A system of computers in network communication where: (i) an end user's computer accesses an instantiation of a virtual machine using remote console software; (ii) the access to the VM is performed through a proxy server; and (iii) by using the proxy server, when the VM instantiation is moved from one physical host computer to another physical host computer, there is no substantial interruption in the access of the VM by the end user through the remote console software.

Abstract: A system of computers in network communication where: (i) an end user's computer accesses an instantiation of a virtual machine using remote console software; (ii) the access to the VM is performed through a proxy server; and (iii) by using the proxy server, when the VM instantiation is moved from one physical host computer to another physical host computer, there is no substantial interruption in the access of the VM by the end user through the remote console software.

Abstract: An image quality control system is disclosed. The example system includes an artificial intelligence modeler to process image data and metadata from patient data to generate first feature(s) from the image data and to parse the metadata to identify study information. The example system includes a computer vision processor to identify second feature(s) in the image data. The example system includes a results evaluator to compare the first feature(s) and second feature(s) to generate a comparison and to evaluate the comparison, first feature(s), and second feature(s) with respect to the study information to generate an evaluation. The example system includes a quality controller to compare the evaluation to quality criterion(-ia) to produce an approval or rejection of the patient data, the approval to trigger release of the patient data and the rejection to deny release of the patient data.

Abstract: Centralized monitoring of plural file systems that operate within or in association with an enterprise computing environment is provided. Each of the plural file systems are provided with a security policy, wherein the security policy defines one or more file system access activities to be monitored at the file system. Each file system is instrumented with a software agent that intercepts the relevant file system access activity. A centralized collector component is operative to receive from each of the plural file systems audit trail data, wherein the audit trail data is data that has been generated locally as file system access activity is intercepted at the file system by the local software agent in accordance with the applicable security policy. The collector applies the security policy against the audit trail data received from at least one of the plural file systems and, in response thereto, takes a given action.

Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a 6,5-heterocyclic structure (e.g., compounds having a imidazopyridine, imidazopyrimidine, imidazopyrazine, imidazopyridazine, imidazotriazine, benzoimidazole, benzotriazole, benzoisoxazole, purine, indazole, triazolotriazine, triazolopyridazine, triazolopyrimidine, triazolopyrazine, triazolotetrazine, triazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolopyridazine, pyrazolotriazine, pyrazolopyridine, isoxazolopyrazine, isoxazolopyrimidine, isoxazolopyrdiazine, isoxazolotriazine, or isoxalopyridine structure) which function as inhibitors of DYRK1A, DYRK1B, and Clk-1, and their use as therapeutics for the treatment of Alzheimer's disease, Down syndrome, diabetes, glioblastoma, autoimmune diseases, cancer (e.g., glioblastoma, prostate cancer), inflammatory disorders (e.g., airway inflammation), and other diseases.

Abstract: Centralized monitoring of plural file systems that operate within or in association with an enterprise computing environment is provided. Each of the plural file systems are provided with a security policy, wherein the security policy defines one or more file system access activities to be monitored at the file system. Each file system is instrumented with a software agent that intercepts the relevant file system access activity. A centralized collector component is operative to receive from each of the plural file systems audit trail data, wherein the audit trail data is data that has been generated locally as file system access activity is intercepted at the file system by the local software agent in accordance with the applicable security policy. The collector applies the security policy against the audit trail data received from at least one of the plural file systems and, in response thereto, takes a given action.

Abstract: Centralized monitoring of plural file systems that operate within or in association with an enterprise computing environment is provided. Each of the plural file systems are provided with a security policy, wherein the security policy defines one or more file system access activities to be monitored at the file system. Each file system is instrumented with a software agent that intercepts the relevant file system access activity. A centralized collector component is operative to receive from each of the plural file systems audit trail data, wherein the audit trail data is data that has been generated locally as file system access activity is intercepted at the file system by the local software agent in accordance with the applicable security policy. The collector applies the security policy against the audit trail data received from at least one of the plural file systems and, in response thereto, takes a given action.

Abstract: Novel tools and techniques for determining suitability and/or desirability of a prospective residence for a user. In some embodiments, a computer might receive a list of real estate listings, each pertaining to, and including a plurality of attributes about, an available home. The computer might collect information about factors relating to a user, generate a user profile based at least in part on the factors, and infer a prioritized list of real estate listing characteristics to satisfy the user based on a prioritized list of user criteria. The computer might subsequently generate and prioritize a list of potential homes from the list of real estate listings, based on comparisons, and at least in part on matches, between the prioritized list of real estate listing characteristics and attributes of at least some potential homes in the listings. The computer might subsequently display the prioritized list of potential homes to the user.