Abstract: Compositions and kits for diagnosing and prognosing Alzheimer's Disease (AD) in a human patient include a binding agent such as a monoclonal antibody for a biomarker conjugated to a detectable moiety such as a fluorophore, wherein the biomarker is chosen from CD163, CD91, CD59, MerTK and other phagocytosis-related molecules. Further compositions and kits employ panels of fluorophore-conjugated monoclonal antibodies for biomarkers including scavenger receptors. Methods for determining the relative expression of biomarkers, diagnosing AD, and determining the efficacy of AD therapeutic candidates such as phagocytosis-promoting agents and scavenger receptor agonists also appear.

Abstract: A system that enables digital distribution of copyrighted sheet music—and allows musician to view the copyrighted sheet music on personal computing devices—while preventing the unauthorized distribution of copyrighted sheet music. An electronic commerce platform provides functionality to purchase copies of copyrighted sheet music. A network security module provides login credentials for purchasers and musicians (and, in some embodiments, limits the number of simultaneous logins). A graphical user interface provides functionality for each purchaser to distribute each purchased copy to one—and only one—musician. In some embodiments, the system allows purchasers to recall sheet music distributed to a first musician and distribute the recalled sheet music to a second musician (without providing functionality for the first musician to view the recalled sheet music).

Abstract: A delivery device is for intermittently delivering materials such as liquids or gels over a sustained period of time to a surface in a controlled way. The surface mountable delivery device is capable of delivering, an antimicrobial agent to protect surfaces from microbial contamination and/or to disinfect surfaces, e.g. door handles, push plates, hand rails, etc. as an aid in preventing and/or hindering the spread of infectious agents. The device uses a vertically lapped nonwoven material as the storage medium for the liquid or gel like materials within the device. A non-wicking liquid mediating layer to controls transfer of liquid from a reservoir to a contact surface of the device to minimize liquid losses. An elastomeric contact liquid delivery layer is optimized for printability. Use of physical features at the device contact surface prevents pore occlusion on user contact and aids flow of liquid to the contact user.

Abstract: A disinfection panel for disinfecting an article facing the disinfection panel is provided. The disinfection panel comprises an interior surface, an exterior surface, a disinfecting member disposed on the interior surface, a first side comprising a first coupling member and a second side comprising a second coupling member. The disinfecting member is configured to disinfect the article facing the disinfection panel. The disinfecting member is any one or more of an ultraviolet (UV) light emitter, an ionizing or non-ionizing radiator, a chemical sprayer, an ozone sprayer, or a heat emitter.

Abstract: A delivery device is for intermittently delivering materials such as liquids or gels over a sustained period of time to a surface in a controlled way. The surface mountable delivery device is capable of delivering, an antimicrobial agent to protect surfaces from microbial contamination and/or to disinfect surfaces, e.g. door handles, push plates, hand rails, etc. as an aid in preventing and/or hindering the spread of infectious agents. The device uses a vertically lapped nonwoven material as the storage medium for the liquid or gel like materials within the device. A non-wicking liquid mediating layer controls transfer of liquid from a reservoir to a contact surface of the device to minimize liquid losses. An elastomeric contact liquid delivery layer is optimized for printability. Use of physical features at the device contact surface prevents pore occlusion on user contact and aids flow of liquid to the contact user.

Abstract: A system, method, and computer program for remotely managing a digital device is provided. One or more digital devices are monitored. At least one matter associated with the one or more digital devices is identified. A resolution to address the at least one matter is generated. The resolution is then distributed from a remote location.

Abstract: A system, method, and computer program is provided which monitors a plurality of digital media devices that are at a remote location. Each of the plurality of digital media devices is associated with a respective plurality of functions. While monitoring the plurality of digital media devices, data is received indicating that a lock mode is to be enabled for the plurality of digital media devices such that a subset of the plurality of functions is disabled. Based on the received data indicating that the lock mode is to be enabled, a command is transmitted to at least one of the plurality of digital media devices to disable the subset of the plurality of functions.

Abstract: A system, method, and computer program for remotely managing a digital device is provided. One or more digital devices are monitored. At least one matter associated with the one or more digital devices is identified. A resolution to address the at least one matter is generated. The resolution is then distributed from a remote location.

Abstract: The invention includes a cermet composition represented by the formula (PQ)(RS) comprising: a ceramic phase (PQ) and a binder phase (RS) wherein, P is a metal selected from the group consisting of Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, W, Fe, Mn and mixtures thereof, Q is carbonitride, R is a metal selected from the group consisting of Fe, Ni, Co, Mn and mixtures thereof, S comprises at least one element selected from Cr, Al, Si and Y.

Abstract: One form of the disclosure includes a cermet composition represented by the formula (PQ)(RS) comprising: a ceramic phase (PQ) and a binder phase (RS) wherein, P is a metal selected from the group consisting of Al, Si, Mg, Ca, Y, Fe, Mn, Group IV, Group V, Group VI elements, and mixtures thereof, Q is oxide, R is a base metal selected from the group consisting of Fe, Ni Co, Mn and mixtures thereof, S consists essentially of at least one element selected from Cr, Al and Si and at least one reactive wetting element selected from the group consisting of Ti, Zr, Hf, Ta, Sc, Y, La, and Ce, wherein the ceramic phase (PQ) ranges from about 55 to 95 vol % based on the volume of the cermet and is dispersed in the binder phase (RS) as particles with a diameter of 100 microns or greater. Another form of the disclosure relates to a bimodal size distribution of the metal oxide ceramic phase within the metal matrix phase.

Abstract: A cermet composition represented by the formula (PQ)(RS)X comprising: a ceramic phase (PQ), a binder phase (RS) and X wherein X is at least one member selected from the group consisting of an oxide dispersoid E, an intermetallic compound F and a derivative compound G wherein said ceramic phase (PQ) is dispersed in the binder phase (RS) as particles of diameter in the range of about 0.5 to 3000 microns, and said X is dispersed in the binder phase (RS) as particles in the size range of about 1 nm to 400 nm.

Abstract: Multimodal cermet compositions comprising a multimodal grit distribution of the ceramic phase and method of making are provided by the present invention. The multimodal cermet compositions include a) a ceramic phase and b) a metal binder phase, wherein the ceramic phase is a metal boride with a multimodal distribution of particles, wherein at least one metal is selected from the group consisting of Group IV, Group V, Group VI elements of the Long Form of The Periodic Table of Elements and mixtures thereof, and wherein the metal binder phase comprises at least one first element selected from the group consisting of Fe, Ni, Co, Mn and mixtures thereof, and at least second element selected from the group consisting of Cr, Al, Si and Y, and Ti.

Abstract: The invention includes a cermet composition represented by the formula (PQ)(RS) comprising: a ceramic phase (PQ) and a binder phase (RS) wherein, P is a metal selected from the group consisting of Si, Mn, Fe, Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, W and mixtures thereof, Q is nitride, R is a metal selected from the group consisting of Fe, Ni, Co, Mn and mixtures thereof, S consists essentially of at least one element selected from Cr, Al, Si, and Y, and at least one reactive wetting aliovalent element selected from the group consisting of Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, W and mixtures thereof.

Abstract: A cermet composition represented by the formula (PQ)(RS) comprising: a ceramic phase (PQ) and binder phase (RS) wherein, P is at least one metal selected from the group consisting of Group IV, Group V, Group VI elements, Q is boride, R is selected from the group consisting of Fe, Ni, Co, Mn and mixtures thereof, S comprises at least one element selected from Cr, Al, Si and Y.

Abstract: A cermet composition represented by the formula (PQ)(RS) comprising: a ceramic phase (PQ) and binder phase (RS) wherein, P is at least one metal selected from the group consisting of Group IV, Group V, Group VI elements, Q is boride, R is selected from the group consisting of Fe, Ni, Co, Mn and mixtures thereof, S comprises at least one element selected from Cr, Al, Si and Y.

Abstract: Cermets are provided in which a substantially stoichiometric metal carbide ceramic phase along with a reprecipitated metal carbide phase, represented by the formula MxCy, is dispersed in a metal binder phase. In MxCy M is Cr, Fe, Ni, Co, Si, Ti, Zr, Hf, V, Nb, Ta, Mo or mixtures thereof, x and y are whole or fractional numerical values with x ranging from 1 to 30 and y from 1 to 6. These cermets are particularly useful in protecting surfaces from erosion and corrosion at high temperatures.

Abstract: The invention includes a cermet composition represented by the formula (PQ)(RS) comprising: a ceramic phase (PQ) and a binder phase (RS) wherein, P is a metal selected from the group consisting of Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, W, Fe, Mn and mixtures thereof, Q is carbonitride, R is a metal selected from the group consisting of Fe, Ni, Co, Mn and mixtures thereof, S comprises at least one element selected from Cr, Al, Si and Y.

Abstract: One embodiment of the invention includes a cermet composition represented by the formula (PQ)(RS) comprising: a ceramic phase (PQ) and a binder phase (RS) wherein, P is a metal selected from the group consisting of Al, Si, Mg, Ca, Y, Fe, Mn, Group IV, Group V, Group VI elements, and mixtures thereof, Q is oxide, R is a base metal selected from the group consisting of Fe, Ni Co, Mn and mixtures thereof, S consists essentially of at least one element selected from Cr, Al and Si and at least one reactive wetting element selected from the group consisting of Ti, Zr, Hf, Ta, Sc, Y, La, and Ce.

Abstract: A method and apparatus for a computer graphics rendering system which slices the traditional geometry pipeline into two phases to improve overall graphics system utilization is described. The graphics system consists of a host processor and a graphics adapter. The host creates work items and feeds them to the graphics adapter. In the two phase method, the first phase computes the clipping status and immediately returns this status information, before completion of the actual clipping, to the application running on the host processor to minimize stalling the host processor and hence the application. The second phase performs the rest of the work necessary to draw the objects on the screen. The advantage of two phase method is that the host processor minimizes its wait (but only for model/view transformation and clipping status determination) for a return status from the graphics adapter for the current work item and gets to create the next work item from the application sooner.

Abstract: While executing the standard graphics processing steps, problem polygons (i.e., those outside of a defined clip volume) are buffered for later processing, while the standard graphics processing continues, without the need for periodically reformatting data and performing clipping. After either a predefined number of polygons have been stored at the buffer location, or at such time as a change in the rendering state occurs, the buffered polygons are clipped.