Abstract: Fuses can store different delay states to cause execution of a command to be staggered for different memory dies of a memory package. Fuse arrays can be included in the memory package and programmed to cause execution of a command to be delayed by different amounts for different dies. The fuse arrays can be fabricated and then programmed to cause different delays for different dies.

Abstract: Techniques are disclosed relating to processor communications fabrics. In some embodiments, a processor includes multiple client circuitry and fabric circuitry that includes at least first and second instances of a tile. The tile may include: client inputs configured to interface with client circuits, tile inputs configured to interface with one or more other tile instances, and communication resources assignable to the client inputs and tile inputs. The communications resources may include: multiple internal links, client outputs configured to interface with client circuits, and tile outputs configured to interface with one or more other tile instances. Control circuitry may, in a given cycle, assign communication resources of a given tile instance to at least a portion of the client inputs and tile inputs for a next cycle, based on priority information. The control circuitry may update priority information based on assignment results over multiple cycles.

Abstract: The present invention provides a computer-implemented method for detecting cell-free DNA (cfDNA), such as circulating tumour DNA, in a DNA-containing sample obtained from a patient, the method comprising: (a) providing loci of interest comprising at least 2 mutation-containing loci representative of a tumour of the patient (“patient-specific loci”); (b) providing sequence data comprising sequence reads of a plurality of polynucleotide fragments from a DNA-containing sample from the patient, wherein said sequence reads span said at least 2 mutation-containing loci of step (a); (c) optionally, performing reads collapsing to group the sequence reads into read families; (d) calculating the mutant allele fraction across some or all of said at least 2 patient-specific loci, optionally wherein the mutant allele fraction is calculated by aggregating mutant reads and total reads; (e) classifying the sample as containing or not containing the target cfDNA based on the calculated mutant allele fraction.

Abstract: A system for facilitating the processing and settlement of a securities trade is provided. The system includes a computer which receives trade execution information indicative of an executed trade by a first trading party and trade allocation information indicative of an executed trade by a second trading party. The system also includes a database of trading party profiles accessible by the computer, the trading party profiles being indicative of acceptable trade parameters for each trading party. Executing on the computer is a matching program for comparing the trade execution information with the trade allocation information and for determining that a match exists if the trade execution information and the trade allocation information correlate within the acceptable trade parameters supplied in the trading party profiles for the first trading party and the second trading party.

Abstract: An apparatus and method, as embodied and broadly described herein, provide a respiratory mask for the application of positive pressure to the airways of a patient. The mask includes two chambers in which a first chamber is maintained with positive pressure with respect to the ambient pressure and contains a first opening which, when in use, is positioned against the patient's face. A second chamber, maintained at negative pressure with respect to the ambient pressure, contains a second opening which, when in use, is positioned against the patient's face, such that the face contacting area of the first opening is smaller than the face contacting area of the second opening.

Abstract: Polymers that are stable under aqueous conditions of high ionic strength are combined with non-fused, silicate based microspheres that are modified with multivalent metals but not washed or dried, said microspheres being present as filters.