Patents by Inventor Christopher Gabel

Christopher Gabel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compact optical sub-assembly with integrated flexible circuit
    Publication number: 20050175299
    Abstract: The invention relates to an optical sub-assembly package for use in receiver optical sub-assemblies or transmitter optical sub-assemblies in which the electrical connections between the transducer chip, e.g. photo-detector or light source, and the device printed circuit board is made by a single flexible circuit conductor extending through the wall of the package. The package is comprised of a housing and a stiffening plate, which encloses and end of the housing and forms a mechanical support for an end of the flexible circuit conductor.
    Type: Application
    Filed: January 25, 2005
    Publication date: August 11, 2005
    Applicant: JDS Uniphase Corporation
    Inventors: Marian Hargis, David Gaio, Roger Lindquist, William Hogan, James Walling, Sundeep Nangalia, Philip Deane, Miles Swain, Christopher Gabel
  • P2x7 receptor-deficient non-human animals and uses thereof
    Publication number: 20050090003
    Abstract: The invention provides non-human, genetically-modified mammals and genetically modified animals cells having a functionally disrupted P2×7 receptor gene. Also provided are methods for producing genetically modified mice in which one or both P2×7R alleles have been functionally inactivated.
    Type: Application
    Filed: October 31, 2003
    Publication date: April 28, 2005
    Applicant: Pfizer, Inc., UNIVERSITY OF NORTH CAROLINA
    Inventors: Christopher Gabel, Beverly Koller
  • Methods of using GST-Omega-2
    Publication number: 20050064519
    Abstract: The present invention relates to GST-Omega-2 and methods of using this diarylsulfonylurea binding protein (DBP) as a therapeutic target for the identification of agents that suppress the release of inflammatory mediators such as interleukin IL-1 and IL-18.
    Type: Application
    Filed: April 5, 2004
    Publication date: March 24, 2005
    Inventors: Christopher Gabel, Kieran Geoghegan, Jose Perez
  • Methods and products for identifying modulators of P2X7 receptor activity, and their use in the treatment of skeletal disorders
    Publication number: 20050054013
    Abstract: Disclosed are methods for screening compounds to identify therapeutic candidates for modulating bone mass and/or bone mineral density, as well as methods for treating skeletal disorders characterized by decreased bone mass and/or bone mineral density. The methods are based upon the identification and use of agonists of the P2X7 receptor.
    Type: Application
    Filed: September 10, 2004
    Publication date: March 10, 2005
    Inventors: HuaZhu Ke, Christopher Gabel