Abstract: The present disclosure provides methods of treating substance use disorders comprising the oral administration mescaline or a salt thereof. In another aspect, the oral administration comprises a pharmaceutical composition comprising synthetic mescaline. The synthetic mescaline, mescaline or salts thereof, and pharmaceutical compositions disclosed herein, provide several advantages over plant extracted mescaline. For example, plant extractions can have varying concentrations of active mescaline leading to dosing variability and potency. In additional embodiments, the administration is accompanied with a preparatory therapy session. In another aspect, the method further comprises a plurality of treatment steps to aid in the efficacy of treating substance use disorders.

Abstract: A system, method and computer-readable storage device are disclosed signing a voicemail and confirming an identity of the speaker. A method includes receiving a request to verify a speaker associated with a communication to a recipient, receiving first data from the speaker in connection with the communication, accessing second data associated with the speaker to verify the speaker, determining whether a match exists between the first data and the second data to yield a determination, retrieving a communication address of the recipient, generating a notification for the recipient, wherein the notification reports on the determination and transmitting the notification to the recipient at the communication address.

Abstract: A system, method and computer-readable storage device are disclosed signing a voicemail and confirming an identity of the speaker. A method includes receiving a request to verify a speaker associated with a communication to a recipient, receiving first data from the speaker in connection with the communication, accessing second data associated with the speaker to verify the speaker, determining whether a match exists between the first data and the second data to yield a determination, retrieving a communication address of the recipient, generating a notification for the recipient, wherein the notification reports on the determination and transmitting the notification to the recipient at the communication address.

Abstract: A system, method and computer-readable storage device are disclosed signing a voicemail and confirming an identity of the speaker. A method includes receiving a request to verify a speaker associated with a communication to a recipient, receiving first data from the speaker in connection with the communication, accessing second data associated with the speaker to verify the speaker, determining whether a match exists between the first data and the second data to yield a determination, retrieving a communication address of the recipient, generating a notification for the recipient, wherein the notification reports on the determination and transmitting the notification to the recipient at the communication address.

Abstract: A method for self-generating an engine-specific model in an engine health monitoring system is provided. The method comprises generating a generic engine model including a generic physics-based model for each of a plurality of engine components in the specific engine; capturing a plurality of observed engine component parameters for each of the plurality of engine components and a plurality of observed environmental parameters during one or more pre-planned training missions; and training an engine-specific model using the plurality of observed engine component parameters and the plurality of environmental parameters captured during the one or more pre-planned training missions, wherein the engine-specific model includes an engine-specific physics-based model for each of the plurality of engine components in the specific engine.

Abstract: According to the invention, there is provided a positive pressure vent for a vehicle. The vent includes an inlet chamber having an air intake port facing into an air stream generated by motion of the vehicle so as to collect air and form a positive pressure inside the inlet chamber. There is further provided a filter adapted to filter air from the inlet chamber of particulate matter. A filtered air path is further provided for allowing filtered air from the filter to travel to the interior of the vehicle under the urging of the positive pressure from the inlet chamber.

Abstract: A slide out kitchen for a vehicle is provided. The slide out kitchen includes an elongate cabinet adapted for moveable, mounting between a closed configuration and an extended configuration. At least one cooktop and an accessory engagement structure to secure kitchen accessories to the cabinet, are also provided.

Abstract: A system, method and computer-readable storage device are disclosed signing a voicemail and confirming an identity of the speaker. A method includes receiving a request to verify a speaker associated with a communication to a recipient, receiving first data from the speaker in connection with the communication, accessing second data associated with the speaker to verify the speaker, determining whether a match exists between the first data and the second data to yield a determination, retrieving a communication address of the recipient, generating a notification for the recipient, wherein the notification reports on the determination and transmitting the notification to the recipient at the communication address.

Abstract: According to the invention, there is provided a positive pressure vent (10) for a vehicle (12). The vent (10) includes an inlet chamber (14) having an air intake port (16) facing into an air stream generated by motion of the vehicle (12) so as to collect air and form a positive pressure inside the inlet chamber (14). There is further provided a filter (18) adapted to filter air from the inlet chamber (14) of particulate matter. A filtered air path (25) is further provided for allowing filtered air from the filter (18) to travel to the interior of the vehicle (12) under the urging of the positive pressure from the inlet chamber (14).

Abstract: The present invention provides a slide out kitchen (10) for a vehicle (12). The slide out kitchen includes an elongate cabinet (14) adapted for moveable mounting between a closed configuration and an extended configuration. At least one cooktop (32) and an accessory engagement means for securing kitchen accessories to the cabinet (14), are also provided. The invention also provides a method of securing the slide out kitchen to a vehicle.

Abstract: A method for self-generating an engine-specific model in an engine health monitoring system is provided. The method comprises generating a generic engine model including a generic physics-based model for each of a plurality of engine components in the specific engine; capturing a plurality of observed engine component parameters for each of the plurality of engine components and a plurality of observed environmental parameters during one or more pre-planned training missions; and training an engine-specific model using the plurality of observed engine component parameters and the plurality of environmental parameters captured during the one or more pre-planned training missions, wherein the engine-specific model includes an engine-specific physics-based model for each of the plurality of engine components in the specific engine.

Abstract: The invention relates to a circuit or microchip for the detection of poor sources of (or very weak) electrical and/or magnetic fields. In one embodiment a device of the present invention includes a microchip consisting of a plate with a plurality of cells, each cell includes a crystal suspended in a semiconducting polymer and piece of metal wire. The cell is insulated by another polymer. A voltage is applied to parallel wires running on each side of the cell, thus inducing a first (or static, or initial) voltage when measured from the cell to the wire. Changes in magnetic or electrical fields are detected by noting a change in voltage from the cell, which is caused by the crystal changing orientation due to the change in the field the circuit is subjected to.

Abstract: The invention relates to a circuit or microchip for the detection of poor sources of (or very weak) electrical and/or magnetic fields. In one embodiment a device of the present invention includes a microchip consisting of a plate with a plurality of cells, each cell includes a crystal suspended in a semiconducting polymer and piece of metal wire. The cell is insulated by another polymer. A voltage is applied to parallel wires running on each side of the cell, thus inducing a first (or static, or initial) voltage when measured from the cell to the wire. Changes in magnetic or electrical fields are detected by noting a change in voltage from the cell, which is caused by the crystal changing orientation due to the change in the field the circuit is subjected to.

Abstract: A real-time diagnostic and fault detection system and method for a gas turbine engine under test in a test cell is disclosed. Sensor data from instrumentation coupled to the gas turbine engine are processed, using a physics-based component level aero-thermal model, to calculate a plurality of engine parameters at a plurality of non-instrumented locations within the gas turbine engine. The plurality of engine parameters are processed to detect when a fault exists and, when a fault does exist, an image is rendered that indicates at least a mostly likely cause for the fault and one or more corrective actions that can be taken to correct the fault. The model is also used to generate projections of engine performance at one or more selected test conditions, and to prognosticate, based on the projections, as to whether the gas turbine engine will actually pass at the one or more selected test conditions.

Abstract: The present invention includes a method for biomimetic-inspired infrared sensors utilizing a bottom up approach. This method includes providing a sinusoidal alternating electrical field between a preformed electrode gap comprising two gold micro-electrodes. Providing single needles of zinc phosphide crystals optimized for growth conditions using a physical vapour transport. Immobilizing at least one individual zinc phosphide nanowire in the preformed electrode gap using dielectrophoretic manipulation. And, placing and contacting the at least one individual zinc phosphide nanowire in the preformed electrode gap. Two nanowires are combined to form a lambda shape for improved sensing.

Abstract: A real-time diagnostic and fault detection system and method for a gas turbine engine under test in a test cell is disclosed. Sensor data from instrumentation coupled to the gas turbine engine are processed, using a physics-based component level aero-thermal model, to calculate a plurality of engine parameters at a plurality of non-instrumented locations within the gas turbine engine. The plurality of engine parameters are processed to detect when a fault exists and, when a fault does exist, an image is rendered that indicates at least a mostly likely cause for the fault and one or more corrective actions that can be taken to correct the fault. The model is also used to generate projections of engine performance at one or more selected test conditions, and to prognosticate, based on the projections, as to whether the gas turbine engine will actually pass at the one or more selected test conditions.

Abstract: The present invention includes a method for biomimetic-inspired infrared sensors utilizing a bottom up approach. This method includes providing a sinusoidal alternating electrical field between a preformed electrode gap comprising two gold micro-electrodes. Providing single needles of zinc phosphide crystals optimized for growth conditions using a physical vapour transport. Immobilizing at least one individual zinc phosphide nanowire in the preformed electrode gap using dielectrophoretic manipulation. And, placing and contacting the at least one individual zinc phosphide nanowire in the preformed electrode gap. Two nanowires are combined to form a lambda shape for improved sensing.

Abstract: Systems and methods for analyzing a sample comprising an analyte selected from a volatile organic compound, a semi-volatile organic compound, a non-volatile organic compound, a polar organic compound and a halogenated non-volatile organic compound are provided. The systems comprises an ionization source, a flow cell or an immersion probe with a delicate membrane, the flow cell or immersion probe for accepting the sample, and the delicate membrane interface in fluid communication with the ionization source and a mass spectrometer. The flow cell system further comprises a simultaneously matched pumping in and out delivery (SMPIOD) system for delivering an acceptor phase comprising the analyte from the delicate membrane interface to the mass spectrometer at a constant acceptor flow pressure and a constant acceptor flow rate.

Abstract: Systems and methods for analyzing a sample comprising an analyte selected from a volatile organic compound, a semi-volatile organic compound, a non-volatile organic compound, a polar organic compound and a halogenated non-volatile organic compound are provided. The systems comprises an ionization source, a flow cell or an immersion probe with a delicate membrane, the flow cell or immersion probe for accepting the sample, and the delicate membrane interface in fluid communication with the ionization source and a mass spectrometer. The flow cell system further comprises a simultaneously matched pumping in and out delivery (SMPIOD) system for delivering an acceptor phase comprising the analyte from the delicate membrane interface to the mass spectrometer at a constant acceptor flow pressure and a constant acceptor flow rate.

Abstract: The invention provides a process for producing a three-dimensional tissue by cultivating eucaryotic cells by introducing the cells into a matrix and cultivating the cells within the matrix in a cell culture medium within a cell culture vessel under controlled dissolved oxygen conditions of the cell culture medium. The matrix contains a support containing an optical oxygen sensor, which is an oxygen-sensitive dye, which upon irradiation with an excitation wavelength changes its emission characteristics in dependence on the dissolved oxygen concentration in the surrounding medium, including a dye phosphorescing upon irradiation of an excitation wavelength, which phosphorescence is quenched by dissolved oxygen.