Abstract: Apparatus, for use at a valve of a heart of a subject, includes a first catheter, a second catheter, and a translation element. The translation element is connected to, and operatively joins, the distal ends of the first catheter and the second catheter. The translation element is operable to translate the distal ends laterally with respect to each other to transition the apparatus between (i) a first state in which the distal ends are held next to each other for transluminal advancement to the heart, and (ii) a second state in which the distal ends are spaced apart from each other for positioning at a first location on the annulus and a second location on the annulus, respectively. The apparatus is configured to, while in the second state, from the distal ends, anchor a first tissue anchor at the first location, and a second tissue anchor at the second location.

Abstract: Porous silicon and methods for preparation and use of the same are disclosed. The porous silicon materials have utility either alone or in combination with other materials, for example, combined with carbon particles for energy storage applications.

Abstract: Generating a cryptographic key, for example using a received external key. A system to generate a cryptographic key may include a first data store which may store an authorization key. A system may include a second data store which may store a secure key and/or a public key. A system may include an access controller, which may allow access to a secure key, for example to an access request which may be accompanied by a digital signature. A system may include a key generator, which may generate a private key, for example using a received external key, a stored authorization key and/or a mapping function. A system may include an access request signal generator which may generate a digital signature and/or which may transmit an access request, for example including a generated digital signature, to an access controller to retrieve a secure key.

Abstract: Generating a cryptographic key, for example using a received external key. A system to generate a cryptographic key may include a first data store which may store an authorization key. A system may include a second data store which may store a secure key and/or a public key. A system may include an access controller, which may allow access to a secure key, for example to an access request which may be accompanied by a digital signature. A system may include a key generator, which may generate a private key, for example using a received external key, a stored authorization key and/or a mapping function. A system may include an access request signal generator which may generate a digital signature and/or which may transmit an access request, for example including a generated digital signature, to an access controller to retrieve a secure key.

Abstract: A computer-implemented method for templating virtual views within an on-demand portal infrastructure is provided. The method includes retrieving a virtual view template identified by a virtual view template identifier in response to a request to render a virtual view of a portal. The method further includes aggregating site profile attributes corresponding to the virtual view with attributes obtained, from the virtual view template referenced by the virtual view template identifier. The attributes obtained from the template profile are distinct from the site profile attributes. The profile attributes and attributes obtained from the virtual view template are used for rendering the virtual view.

Abstract: The present invention provides a method, system, and computer program product for providing virtual views in an on-demand portal infrastructure. The method comprises: receiving one of a plurality of different virtual view identifiers; retrieving a site profile associated with the received virtual view identifier; and uniquely rendering a concrete portal site based on information in the site profile to generate a virtual view of the concrete portal site, wherein a different virtual view of the concrete portal site is rendered for each of the plurality of different virtual view identifiers.

Abstract: The use of a lipid in oxidised form for the manufacture of a medicament for therapeutically neutralising (i.e. reducing or substantially destroying the activity of) an organoboronate drug. The lipid may be an HDL hydroperoxide. The drug may be TRI 50c or a salt or prodrug thereof.

Abstract: Compounds, useful as protease inhibitors, of the formula (I): where: Ar is a ring or ring system, for example a benzene ring, and may be substituted by one or more moieties in addition to X and LJ; X is a functional group which is a hydrogen-bond acceptor, e.g. a nitro or boronate group BY1Y2; L is a linker, most preferably (CR5R6)—S—; J is a moiety containing a basic nitrogen atom but not containing an amino acid residue, preferably amidino, guanidine, amino carboxamido, hydroxylamino, or imidazolyl, or an N-substituted analogue thereof.

Abstract: There is described an apparatus for generating a cryptographic key using data representative of an analogue source. The apparatus has a number generator which processes the data representative of the analogue source to generate an intermediate key, the intermediate key being a number, and a data store for storing a mapping key, the mapping key being a number predetermined to combine with the intermediate key in accordance with a monotonic mapping function to generate a desired cryptographic key. Preferably, the number generator processes the data representative of an analogue source in accordance with stored process data, determined by a training process, which indicates attributes of the data whose values are to be measured and adjustment data for adjusting the values to improve the repeatability of generation of the intermediate key.

Abstract: There are described processes for the preparation of a compound of formula I and novel intermediates in the preparative process.

Abstract: There are described processes for the preparation of a compound of formula I and novel intermediates in the preparative process.

Abstract: There are described processes for the preparation of a compound of formula I ##STR1## and novel intermediates in the preparative process.

Abstract: There are described processes for the preparation of a compound of formula I ##STR1## and novel intermediates in the preparative process.

Abstract: There are described processes for the preparation of a compound of formula I ##STR1## and novel intermediates in the preparative process.

Abstract: There are described processes for the preparation of a compound of formula I ##STR1## and novel intermediates in the preparative process.

Abstract: There are described processes for the preparation of a compound of formula I ##STR1## and novel intermediates in the preparative process.