Patents by Inventor Christopher H. Bachran

Christopher H. Bachran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cytolethal distending toxin subunit B conjugated or fused to toxin lethal factor
    Patent number: 9890369
    Abstract: Disclosed is a protein comprising a cytolethal distending toxin subunit B (CdtB) conjugated or fused to a Bacillus anthracis toxin lethal factor (LF) or a functional portion of LF. Related chimeric molecules, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, pharmaceutical compositions, methods of treating or preventing cancer, and methods of inhibiting the growth of a target cell are also disclosed.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: February 13, 2018
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Christopher H. Bachran, Stephen H. Leppla
  • CYTOLETHAL DISTENDING TOXIN SUBUNIT B CONJUGATED OR FUSED TO BACILLUS ANTHRACIS TOXIN LETHAL FACTOR
    Publication number: 20160145590
    Abstract: Disclosed is a protein comprising a cytolethal distending toxin subunit B (CdtB) conjugated or fused to a Bacillus anthracis toxin lethal factor (LF) or a functional portion of LF. Related chimeric molecules, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, pharmaceutical compositions, methods of treating or preventing cancer, and methods of inhibiting the growth of a target cell are also disclosed.
    Type: Application
    Filed: June 19, 2014
    Publication date: May 26, 2016
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Christopher H. Bachran, Stephen H. Leppla