Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that treat insulin resistance-induced physiological disorders by modulating G-protein coupled receptor (GPCR) and transient receptor potential (TRP) ion channel activity. Also disclosed herein are methods for using the compositions to treat cardiovascular disorders, such as atherosclerosis.

Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, which modulate insulin secretion, suppress appetite, and reduce body mass by activating G-protein coupled receptors (GPCRs), such as ectopic olfactory receptors, and transient receptor potential (TRP) ion channels. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes and obesity.

Abstract: The present invention relates to a sponge dressing for treating wounds comprised of a polymer sponge containing a plurality of antimicrobial dyes with at least one dye being gram positive and at least one other dye being gram negative and a silicon adhesive secured to a sponge surface. The sponge dressing can be exposed initially to gamma radiation and later sterilized by ethylene oxide or alternatively it can be sterilized by ethylene oxide and later irradiated by gamma radiation. The sponge dressing has a morphology characterized by an average pore throat diameter of 0.5-500 ?m and a porosity ranging from about 60% to about 99.5%. The sponge dressing can also contain at least one biofilm reducing agent, at least one chelating agent and an ionic and non-ionic surfactant.

Abstract: Fenestration units including a movable sash located within a fenestration unit frame are described herein. The fenestration units further include structures configured to retain the movable sash within the frame with the structures being configured to form mechanical interlocks with the fenestration unit frame when the movable sash is in a closed position within the fenestration unit frame.

Abstract: Disclosed herein are compounds and ligands, and antihypertensive compositions formed therewith, that modulate seminal endocrine factors that control blood pressure and, thereby, treat hypertension. Also disclosed herein are methods for using the antihypertensive compositions to treat hypertension and disorders associated therewith.

Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin and, some instances, dopamine secretion by activating endogenous receptors. Also disclosed herein are methods for using the compositions to treat neurodegenerative disorders, such as Parkinson's disease.

Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin secretion by activating endogenous receptors. Also disclosed herein are methods for using the compositions to treat cardiovascular disorders.

Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin secretion and suppress appetite by activating ectopic olfactory receptors. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes, and disorders, such as abnormal insulin secretion.

Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate seminal endocrine factors that control blood pressure and, thereby, treat hypertension. Also disclosed herein are methods for using the compositions to treat hypertension and disorders associated therewith.

Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin secretion and suppress appetite by activating ectopic olfactory receptors. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes, and disorders, such as abnormal insulin secretion.

Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin secretion and suppress appetite by activating ectopic olfactory receptors. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes, and disorders, such as abnormal insulin secretion.

Abstract: Compound fenestration assembly mull joints using joining strips and compound fenestration assemblies using those mull joints are described herein. The joining strips used in the compound fenestration assembly mull joints described herein are configured to improve the strength of the mull joints in which they are used and, therefore, the ability of the resulting compound fenestration assemblies to maintain integrity when subjected to, e.g., wind loads and other forces is improved. The benefits of the mull joints and the compound fenestration assemblies incorporating them as described herein may be enhanced with an increase in the number of adjacent fenestration units (and, therefore, mull joints) in a given compound fenestration assembly.

Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin secretion and suppress appetite by activating ectopic olfactory receptors. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes, and disorders, such as abnormal insulin secretion.

Abstract: Disclosed herein are compounds and ligands, and antihypertensive compositions formed therewith, that modulate seminal endocrine factors that control blood pressure and, thereby, treat hypertension. Also disclosed herein are methods for using the antihypertensive compositions to treat hypertension and disorders associated therewith.

Abstract: Disclosed herein are compounds and ligands, and antihypertensive compositions formed therewith, that modulate seminal endocrine factors that control blood pressure and, thereby, treat hypertension. Also disclosed herein are methods for using the antihypertensive compositions to treat hypertension and disorders associated therewith.

Abstract: Contain and drain sill systems and fenestration unit incorporating the sills along with related methods are described herein. The contain and drain sill systems and fenestration units incorporating them provide enhanced water performance by separating drainage from interior and exterior sides of the fenestration unit and sill system.

Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin secretion and suppress appetite by activating ectopic olfactory receptors. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes, and disorders, such as abnormal insulin secretion.

Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin secretion and suppress appetite by activating ectopic olfactory receptors. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes, and disorders, such as abnormal insulin secretion.