Abstract: A method and system for attenuating a shockwave propagating through a first medium. The method and system may include providing a sensor for detecting a shockwave-producing event, which may include detecting an explosive device or detecting an explosion from an explosive device, determining a direction and distance of the shockwave relative to a defended target, calculating with a computer control a firing plan, and interposing a second medium between the shockwave and a protected asset if cost effective to do so. The second medium may be different from the first medium and the shockwave may be reflected, refracted and dispersed, or absorbed as it passes through the second medium prior to reaching the protected asset, and thus may be attenuated in force as it reaches the protected asset.

Abstract: The invention provides novel deazaxanthine and deazahypoxanthine compounds. The compounds may be useful in the therapy of diseases and conditions in which dipeptidylpeptidase-IV (DPP-IV) is implicated.

Abstract: The present invention relates to novel pyrimidine compounds, for the modulation of the histamine H4 receptor and the treatment or prevention of conditions mediated by the histamine H4 receptor. The invention also relates to the preparation of such compounds.