Patents by Inventor Christopher Hosfield

Christopher Hosfield has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7236891
    Abstract: The present invention provides methods for determining the structure and/or function of one or more domains of a cation-dependent (and preferably calcium-dependent) polypeptide (particularly a calcium-dependent enzyme, which may be a protease such as calpain) in the presence of one or more cations. The invention further provides methods for identifying a ligand having the ability to bind to one or more ligand-binding domains (LBDs) of a cation-dependent (and preferably calcium-dependent) polypeptide, and ligands identified by these methods. The invention also provides methods of treating or preventing physical disorders in animals using these ligands.
    Type: Grant
    Filed: May 30, 2002
    Date of Patent: June 26, 2007
    Assignee: Queen's University at Kingston
    Inventors: Peter L. Davies, John S. Elce, Christopher Hosfield, Zongchao Jia, Tudor Moldoveanu
  • Publication number: 20030017984
    Abstract: The present invention provides methods for determining the structure and/or function of one or more domains of a cation-dependent (and preferably calcium-dependent) polypeptide (particularly a calcium-dependent enzyme, which may be a protease such as calpain) in the presence of one or more cations. The invention further provides methods for identifying a ligand having the ability to bind to one or more ligand-binding domains (LBDs) of a cation-dependent (and preferably calcium-dependent) polypeptide, and ligands identified by these methods. The invention also provides methods of treating or preventing physical disorders in animals using these ligands.
    Type: Application
    Filed: May 30, 2002
    Publication date: January 23, 2003
    Inventors: Peter L. Davies, John S. Elce, Christopher Hosfield, Zongchao Jia, Tudor Moldoveanu