Abstract: A system for sending topic-specific digital messages from professionals to their clients with information that is more relevant and applicable to the needs of the recipients based upon prior interactions with the professional.

Abstract: Systems and methods are provided for fabricating composite parts. One embodiment is a method of fabricating a composite part. The method includes providing a preform on a tool mandrel, positioning sensors around the preform according to a target shape of the composite part, and sealing the preform with a vacuum bag to form a chamber. The method also includes applying temperature and pressure to the chamber to infuse a resin into the preform to create a composite preform undergoing infusion, monitoring a thickness of the composite preform prior to completing cure, and adjusting at least one of the temperature and the pressure prior to completing cure based on the thickness.

Abstract: Systems and methods are provided for fabricating composite parts. One embodiment is a method of fabricating a composite part. The method includes providing a preform on a tool mandrel, positioning sensors around the preform according to a target shape of the composite part, and sealing the preform with a vacuum bag to form a chamber. The method also includes applying temperature and pressure to the chamber to infuse a resin into the preform to create a composite preform undergoing infusion, monitoring a thickness of the composite preform prior to completing cure, and adjusting at least one of the temperature and the pressure prior to completing cure based on the thickness.

Abstract: A tool and its method of use, where at least one channel is formed in a tool surface of a tool and one or more grooves are formed in at least one surface of a mandrel that is dimensioned to be positioned in the channel. The grooves formed in the mandrel and the channel in the tool surface distribute and deliver resins supplied to the tool surface through layers of fiber reinforced material positioned on the tool surface and in the channel, and position over the mandrel. The grooves formed in the mandrel and the channel formed in the tool surface direct a flow of liquid resin and infuse the layers of fiber reinforced material with the liquid resin.

Abstract: A directional cold spray nozzle defines a flow passageway that includes a bend for redirecting flow from a first flow direction to a second flow direction different from the first flow direction, wherein the flow passageway is divergent through at least a portion of the bend. The flow passageway may be convergent prior to becoming divergent in the path of flow. The directional cold spray nozzle simultaneously accelerates the powder and carrier gas and changes the spray direction of the spray plume to reach interior bore surfaces and other surfaces that are difficult or impossible to reach with a straight nozzle.

Abstract: A directional cold spray nozzle defines a flow passageway that includes a bend for redirecting flow from a first flow direction to a second flow direction different from the first flow direction, wherein the flow passageway is divergent through at least a portion of the bend. The flow passageway may be convergent prior to becoming divergent in the path of flow. The directional cold spray nozzle simultaneously accelerates the powder and carrier gas and changes the spray direction of the spray plume to reach interior bore surfaces and other surfaces that are difficult or impossible to reach with a straight nozzle.

Abstract: A plastic container including an upper portion, a base, a plurality of surface features, and a substantially cylindrical portion. The upper portion has a mouth defining an opening into the container. The base is movable to accommodate vacuum forces generated within the container thereby decreasing the volume of the container. The plurality of surface features are included with the base and are configured to accommodate vacuum forces. The substantially cylindrical portion extends between the upper portion and the base.

Abstract: A mold for forming a plastic container having an integrally formed standing ring. The mold includes a first mold portion and a second mold portion. The second mold portion is movable relative to the first mold portion. The first mold portion and the second mold portion together define at least in part a mold cavity for molding a plastic container. The first mold portion and the second mold portion together define a standing ring slot for forming a standing ring on a base portion of the plastic container. The standing ring slot is defined at an interface between the first mold portion and the second mold portion.

Abstract: A one-piece plastic container includes a body defining a longitudinal axis and having an upper portion, a sidewall portion and a base portion. The upper portion has a spout defining an opening into the container and a finish offset radially outwardly from the spout. A trough defines a passage into the body. The trough slopes toward the passage and defines a non-orthogonal angle relative to the longitudinal axis. According to other features, the sidewall portion is integrally formed with and extends from the upper portion to the base portion. The base portion closes off an end of the container. The finish defines a means, such as at least one thread, for attaching a closure thereon.

Abstract: A mold for forming a plastic container having an integrally formed standing ring. The mold includes a first mold portion and a second mold portion. The second mold portion is movable relative to the first mold portion. The first mold portion and the second mold portion together define at least in part a mold cavity for molding a plastic container. The first mold portion and the second mold portion together define a standing ring slot for forming a standing ring on a base portion of the plastic container. The standing ring slot is defined at an interface between the first mold portion and the second mold portion.

Abstract: A plastic container including an upper portion, a base, a plurality of surface features, and a substantially cylindrical portion. The upper portion has a mouth defining an opening into the container. The base is movable to accommodate vacuum forces generated within the container thereby decreasing the volume of the container. The plurality of surface features are included with the base and are configured to accommodate vacuum forces. The substantially cylindrical portion extends between the upper portion and the base.

Abstract: A container body and base being lightweight structures designed to accommodate vacuum forces either simultaneously or in sequence. The container body and base each absorb a significant percentage of the vacuum. By utilizing a lightweight base design to absorb a portion of the vacuum forces enables an overall light-weighting, design flexibility, and effective utilization of alternative vacuum absorbing capabilities on the container body.

Abstract: A blow-molded plastic container comprising a base portion having a flexible standing ring radially extending therefrom. The flexible standing ring is disposed about a lowest most portion of the container and operable to support the container on a surface. The flexible standing ring defines an annular groove thereabout that collapses in response to internal vacuum forces and/or external loading forces. The container further comprises a body portion that extends from an upper portion to the base, such that the upper portion, the body portion and the base cooperate to define a receptacle chamber within the container into which product can be filled.

Abstract: A one-piece plastic container includes a body defining a longitudinal axis and having an upper portion, a sidewall portion and a base portion. The upper portion has a spout defining an opening into the container and a finish offset radially outwardly from the spout. A trough defines a passage into the body. The trough slopes toward the passage and defines a non-orthogonal angle relative to the longitudinal axis. According to other features, the sidewall portion is integrally formed with and extends from the upper portion to the base portion. The base portion closes off an end of the container. The finish defines a means, such as at least one thread, for attaching a closure thereon.

Abstract: A container body and base being lightweight structures designed to accommodate vacuum forces either simultaneously or in sequence. The container body and base each absorb a significant percentage of the vacuum. By utilizing a lightweight base design to absorb a portion of the vacuum forces enables an overall light-weighting, design flexibility, and effective utilization of alternative vacuum absorbing capabilities on the container body.

Abstract: This invention is directed to a method for isolating and/or purifying one or more taxanes from materials comprising taxanes. In one embodiment, the method comprises the steps of: (a) treating a taxane containing material with an amino containing material attached to a solid matrix, such as a polyethyleneimine-bonded silica chromatographic resin; (b) eluting the desired taxane compound from the resin; and (c) recovering the eluted taxane compound.

Abstract: A process for harvesting yew biomass and a process of making Yew pellets from Yew tree material is disclosed herein. The process for harvesting comprising the steps of (i) harvesting the tops or roots of the Yew tree; (ii) washing the harvested material; (iii) drying the harvested material; and (iv) grinding the harvested material into a fine powder. The process for making Yew pellets comprising the steps of (i) adding from about 1% to about 20% w/w water to the Yew tree material; and (ii) compressing the Yew tree material in a die to form a pellet whereby the resulting pellet has a final moisture content of less than 10% by weight. The yew pellets produced herein are suitable for extracting taxane molecules from the pellets.

Abstract: A laser system (10) is disclosed comprising a laser device (1) for emitting laser radiation and an optical fiber (2) adapted to connect, in use, to the laser device (1) for delivering the laser radiation. The optical fibre contains a label (3), such as an RF identification tag, a barcode or a colour code. The laser device (1) interrogates the optical fibre (2) and receives information back from the optical fibre (2). If the usage of the optical fibre (2) has exceeded safety limits then the laser device (1) may be prevented from operating. The laser device (1) on receiving information from the optical fibre (2) may also be configured to deliver laser radiation having a specific power, pulse width, pulse interval and treatment duration.