Abstract: A downlead cable includes a first connector configured to connect to a headset of a communication system. A second connector is configured to connect to a connection port of a handset or a radio system. The downlead cable further includes wires connecting the first and second connectors and a cable jacket encapsulating the wires. A transformer is wired inline between the first and second connectors. The transformer is configured to enable the headset to mimic the electrical characteristics a microphone which the handset or the radio system is configured to interface.

Abstract: A downlead cable includes a first connector configured to connect to a headset of a communication system. A second connector is configured to connect to a connection port of a handset or a radio system. The downlead cable further includes wires connecting the first and second connectors and a cable jacket encapsulating the wires. A transformer is wired inline between the first and second connectors. The transformer is configured to enable the headset to mimic the electrical characteristics a microphone which the handset or the radio system is configured to interface.

Abstract: An earplug includes a housing and a receiver positioned in the housing. The receiver may be configured to receive a wireless audio signal from an audio source external to the earplug and convert the wireless audio signal to an electrical audio signal. The earplug may include a speaker configured to receive electrical audio signal from the receiver and convert the electrical audio signal into audible sound output from a speaker port. The earplug may include a projection including an opening that defines at least a portion of a sound channel from the speaker. The projection may receive the audible sound output from the speaker and output the audible sound out of the earplug. The earplug may include earplug padding configured to form a seal with a user's ear canal. The earplug may include an acoustic vent positioned in the sound channel, including a waterproof membrane extending across the channel.

Abstract: An earplug includes a housing and a receiver positioned in the housing. The receiver may be configured to receive a wireless audio signal from an audio source external to the earplug and convert the wireless audio signal to an electrical audio signal. The earplug may include a speaker configured to receive electrical audio signal from the receiver and convert the electrical audio signal into audible sound output from a speaker port. The earplug may include a projection including an opening that defines at least a portion of a sound channel from the speaker. The projection may receive the audible sound output from the speaker and output the audible sound out of the earplug. The earplug may include earplug padding configured to form a seal with a user's ear canal. The earplug may include an acoustic vent positioned in the sound channel, including a waterproof membrane extending across the channel.

Abstract: The present disclosure provides a method for enhancing or inducing an immune response and/or for inducing lysis of cancer cells and/or for treating cancer in a subject, the method comprising administering to the subject a compound that neutralizes BTN2A1 and/or that binds to BTN2A1 on the cells and induces death of the cells.

Abstract: A headset communication system with improved functionality. The headset communication system may include hear-through limiter functionality. The headset communication system may include failsafe functionality. The headset communication system may include multichannel, mixing, passive push-to-talk functionality. The headset communication system may include near field magnetic induction functionality.

Abstract: A blood sampling device includes a housing and a lancet supporting a lancet needle or tip, the lancet and needle being urged or urgeable in a pricking direction. A trigger mechanism is moveable to a fire position for releasing the lancet to travel in the pricking direction. A removable safety cap initially covers the lancet needle. The lancet has an initial position in which movement of the trigger mechanism to its fire position is blocked and an intermediate position in which the trigger mechanism may be moved to its fire position. The intermediate position is obtainable only on removal of the safety cap.

Abstract: The present disclosure provides computer-implemented methods of organising the marketing of a compound that neutralises BTN2A1.

Abstract: Improvements in and relating to blood sampling devices A blood sampling device includes a housing and a lancet supporting a lancet needle or tip, the lancet and needle being urged or urgeable in a pricking direction. A trigger mechanism is moveable to a fire position for releasing the lancet to travel in the pricking direction. A removable safety cap initially covers the lancet needle. The lancet has an initial position in which movement of the trigger mechanism to its fire position is blocked and an intermediate position in which the trigger mechanism may be moved to its fire position. The intermediate position is obtainable only on removal of the safety cap.

Abstract: A blood sampling device includes a housing and a lancet supporting a lancet needle or tip, the lancet and needle being urged or urgeable in a pricking direction. A trigger mechanism is moveable to a fire position for releasing the lancet to travel in the pricking direction. A removable safety cap initially covers the lancet needle. The lancet has an initial position in which movement of the trigger mechanism to the fire position is blocked and an intermediate position in which the trigger mechanism may be moved to the fire position. The intermediate position is obtainable only on removal of the safety cap.

Abstract: A lancing device includes a housing (10, 12) and a lancet holder movably mounted within the housing. The lancet holder has a forward portion defining a socket (30) for partially surrounding and retaining in use the rear portion of a lancet. A lancet release element (40, 42) can be moved forward to cooperate with lugs on the socket to expand it to allow insertion and/or removal of the lancet with minimal insertion or withdrawal force.

Abstract: The present disclosure provides a method for enhancing or inducing an immune response and/or for inducing lysis of cancer cells and/or for treating cancer in a subject, the method comprising administering to the subject a compound that neutralizes BTN2A1 and/or that binds to BTN2A1 on the cells and induces death of the cells.

Abstract: Apparatus for loading into an injection device and comprising a syringe and a boot remover. The syringe has a syringe body, a needle and a boot providing a sterile cover for the needle. The boot remover has a body for substantially enclosing the boot and a lip or lips projecting inwardly to engage a junction between the boot and the syringe body. The boot remover also has, at its widest point, substantially the same outer dimension as, or a smaller outer dimension than, the syringe body. The apparatus can be loaded into an injection device through an opening at a distal end of the device such that, when loaded, a portion of the boot remover projects through a proximal end of the device to facilitate removal of the boot remover and boot by a user. This arrangement allows a user to remove the boot from the syringe by holding and pulling on said grip.

Abstract: Polyamide sample preparation tubes with a hollow polyamide tube and an extraction medium contained within the tube are utilized in the sample preparation devices. The sample preparation tubes are substantially inert and show little tendency to dissolve or leach contaminants into nonaqueous liquids. The polyamide tubes may be used in preparing samples for analytical procedures such as GC, GC/MS, LC or LC/MS.

Abstract: A lancing device includes a housing (10, 12) and a lancet holder movably mounted within the housing. The lancet holder has a forward portion defining a socket (30) for partially surrounding and retaining in use the rear portion of a lancet. A lancet release element (40, 42) can be moved forward to cooperate with lugs on the socket to expand it to allow insertion and/or removal of the lancet with minimal insertion or withdrawal force.

Abstract: A blood sampling device includes a housing and a lancet supporting a lancet needle or tip, the lancet and needle being urged or urgeable in a pricking direction. A trigger mechanism is moveable to a fire position for releasing the lancet to travel in the pricking direction. A removable safety cap initially covers the lancet needle. The lancet has an initial position in which movement of the trigger mechanism to its fire position is blocked and an intermediate position in which the trigger mechanism may be moved to its fire position. The intermediate position is obtainable only on removal of the safety cap.

Abstract: In a first aspect, the invention relates to an apparatus for inducing or maintaining a target end tidal concentration of a gas in a subject comprising a breathing circuit, a source of gas flow into the circuit, means for controlling the rate of the source of gas flow into the circuit and means for controlling the concentration of gases in the source gas flow independently from each other. In another aspect, the invention relates to a method of preparing an apparatus for inducing or maintaining a target end tidal concentration of a gas X in a subject comprising selecting a rate of a source gas flow into a breathing circuit, selecting the concentration of at least one constituent gas of a component gas making up the source gas to a level corresponding to the end tidal concentration of the gas X, whereby the apparatus is adapted to administer a source gas having a first gas composition.