Abstract: A training device for the preparation, execution and maintenance of central venous catheters comprising a central block including a cavern traversing through the block, a tube running through the cavern, a reservoir containing a liquid with a distal end of the tube engaged with the reservoir, a covering material secured over the central block, a guidewire extended through the covering material and within the tube, a hydraulic or pneumatic device operationally associated with the reservoir and allowing the reservoir and the tube to be filled and pressurized with the liquid, a scalpel or similar instrument for making a small incision in the covering material at the site where the guide wire extends through the covering material, a dilator to expand the incision opening and then remove from the incision and guidewire and a catheter to feed over the guidewire and into the incision.

Abstract: A training device for the preparation, execution and maintenance of central venous catheters comprising a central block including a cavern traversing through the block, a tube running through the cavern, a reservoir containing a liquid with a distal end of the tube engaged with the reservoir, a covering material secured over the central block, a guidewire extended through the covering material and within the tube, a hydraulic or pneumatic device operationally associated with the reservoir and allowing the reservoir and the tube to be filled and pressurized with the liquid, a scalpel or similar instrument for making a small incision in the covering material at the site where the guide wire extends through the covering material, a dilator to expand the incision opening and then remove from the incision and guidewire and a catheter to feed over the guidewire and into the incision.

Abstract: A system, method, and network through which a Wi-Fi hot spot provider provides Internet access to users in exchange for the right to send marketing messages to the user from vendors. The Wi-Fi hot spot provider charges vendors for delivering marketing messages and ensures that access is limited to user-agreed parameters. The system, method, and network uses cellular telephone text messaging in a way that integrates location based advertising and text based advertising. The system, method, and network creates opportunities for up-sell by delivering marketing messages and offers to users who actually visited the particular venue and may still be present in the venue; tracking the user's participation and response to marketing messages in order to direct further marketing after the user has left the venue; and having knowledge of past marketing messages when the user re-appears at an event or at a similar event.

Abstract: The invention provides methods for determining a prognosis of colorectal cancer in an individual comprising determining an A-type lamin status of an individual and using the A-type lamin status to determine the prognosis of the colorectal cancer, and more particularly for predicting outcomes of colorectal cancer in the individual such as the survival or mortality of the individual or the likelihood of recurrence of the colorectal cancer. Kits for use in carrying out these methods are also provided.

Abstract: A method of assessing cognitive impairment of a user includes presenting a visual test stimulus to the user for a pre-determined test stimulus exposure duration. The test stimulus is then masked and a response from the user is measured. The response provides information about the user's perception of a characteristic of the test stimulus together with the time taken for the user to respond. These steps are repeated to develop a user profile and cognitive impairment in the user is assessed by comparing the user profile with a reference profile. A method of assessing cognitive impairment of a user includes presenting a visual test stimulus to the user for a pre-determined test stimulus exposure duration. The test stimulus is then masked and a response from the user is measured. The response provides information about the user's perception of a characteristic of the test stimulus together with the time taken for the user to respond.