Patents by Inventor Christopher J. Ackerson
Christopher J. Ackerson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11291203Abstract: A product includes a metallogel material having metal ions dispersed in an assembly having an organic compound. A method includes combining a metal salt, an organic compound precursor, and a glyme for forming a metallogel material having metal ions dispersed in an assembly having an organic compound.Type: GrantFiled: December 6, 2019Date of Patent: April 5, 2022Assignees: Lawrence Livermore National Security, LLC, Colorado State University Research FoundationInventors: William Compel, Keith Morrison, James Armstrong, Christopher J. Ackerson
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Publication number: 20210311066Abstract: Enzymes that reduce specific metal or metalloid ions to insoluble form are important to science. Peptides isolated from yeast- and phage-display libraries can affect the size and morphology of inorganic materials during their synthesis. Herein, an Se binding peptide was fused to an enzyme capable of reducing selenite (SeO32?) to a Se0 nanoparticle (SeNP). The fusion of the Se binding peptide to the metalloid reductase provided size control of the resulting SeNP. The SeNP product also remains associated to the enzyme fusion. The Se binding peptide fusion to the enzyme increases the enzyme's SeO32? reductase activity. Modification of enzyme activity was absent, and the size control of particles was diminished when the Se binding peptide was added exogenously to the reaction mixture. Binding of the peptide is attributed to His based ligation that results in a conformational change to the peptide.Type: ApplicationFiled: August 9, 2019Publication date: October 7, 2021Applicant: Colorado State University Research FoundationInventors: Christopher J. ACKERSON, Zachary BUTZ, Richard NEMETH, Ryan RISKOWSKI, Kanda BORGOGNONI
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Publication number: 20210130552Abstract: The invention provides a metallopolymer coordination network comprising one or more coinage or similar metals and in some embodiments, a glyme or glyme-equivalent. The composition has an amorphous polymer network that is significantly stronger than previously reported supramolecular hydrogels synthesized without glyme. Glyme chain length and water content strongly influence the mechanical, electronic, and optical behavior of the network.Type: ApplicationFiled: December 21, 2020Publication date: May 6, 2021Applicant: COLORADO STATE UNIVERSITY RESEARCH FOUNDATIONInventors: William Scott Compel, Christopher J. Ackerson, O. Andrea Wong
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Publication number: 20210051948Abstract: A product includes a metallogel material having metal ions dispersed in an assembly having an organic compound. A method includes combining a metal salt, an organic compound precursor, and a glyme for forming a metallogel material having metal ions dispersed in an assembly having an organic compound.Type: ApplicationFiled: December 6, 2019Publication date: February 25, 2021Inventors: William Compel, Keith Morrison, James Armstrong, Christopher J. Ackerson
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Patent number: 10875970Abstract: The invention provides a metallopolymer coordination network comprising one or more coinage or similar metals and a glyme or glyme-equivalent. The composition has an amorphous polymer network that is significantly stronger than previously reported supramolecular hydrogels synthesized without glyme. Glyme chain length and water content strongly influence the mechanical, electronic, and optical behavior of the network.Type: GrantFiled: November 21, 2019Date of Patent: December 29, 2020Assignee: Colorado State University Research FoundationInventors: William Scott Compel, Christopher J. Ackerson, O. Andrea Wong
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Publication number: 20200087463Abstract: The invention provides a metallopolymer coordination network comprising one or more coinage or similar metals and a glyme or glyme-equivalent. The composition has an amorphous polymer network that is significantly stronger than previously reported supramolecular hydrogels synthesized without glyme. Glyme chain length and water content strongly influence the mechanical, electronic, and optical behavior of the network.Type: ApplicationFiled: November 21, 2019Publication date: March 19, 2020Applicant: COLORADO STATE UNIVERSITY RESEARCH FOUNDATIONInventors: William Scott Compel, Christopher J. Ackerson, O. Andrea Wong
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Patent number: 10487181Abstract: The invention provides a metallopolymer coordination network comprising one or more coinage or similar metals and a glyme or glyme-equivalent. The composition has an amorphous polymer network that is significantly stronger than previously reported supramolecular hydrogels synthesized without glyme. Glyme chain length and water content strongly influence the mechanical, electronic, and optical behavior of the network.Type: GrantFiled: December 2, 2016Date of Patent: November 26, 2019Assignee: Colorado State University Research FoundationInventors: William Scott Compel, Christopher J. Ackerson, O. Andrea Wong
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Patent number: 9683992Abstract: The invention provides novel gold nanoclusters of the formula Au20(SR)15(weak ligand), wherein each R is independently an organic group, and the weak ligand is a weakly associating gold ligand of Formula I as described herein. The nanocluster can have an approximate molecular weight of 6 kDa. Corresponding dimers of the nanocluster can have an approximate molecular weight of 10 kDa (by SEC). The invention also provides methods of making and using the gold nanoclusters.Type: GrantFiled: July 31, 2014Date of Patent: June 20, 2017Assignee: Colorado State University Research FoundationInventors: William S. Compel, Christopher J. Ackerson, On Lo A. Wong
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Publication number: 20170158824Abstract: The invention provides a metallopolymer coordination network comprising one or more coinage or similar metals and a glyme or glyme-equivalent. The composition has an amorphous polymer network that is significantly stronger than previously reported supramolecular hydrogels synthesized without glyme. Glyme chain length and water content strongly influence the mechanical, electronic, and optical behavior of the network.Type: ApplicationFiled: December 2, 2016Publication date: June 8, 2017Applicant: COLORADO STATE UNIVERSITY RESEARCH FOUNDATIONInventors: William Scott Compel, Christopher J. Ackerson, O. Andrea Wong
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Publication number: 20150037585Abstract: The invention provides novel gold nanoclusters of the formula Au20(SR)15(weak ligand), wherein each R is independently an organic group, and the weak ligand is a weakly associating gold ligand of Formula I as described herein. The nanocluster can have an approximate molecular weight of 6 kDa. Corresponding dimers of the nanocluster can have an approximate molecular weight of 10 kDa (by SEC). The invention also provides methods of making and using the gold nanoclusters.Type: ApplicationFiled: July 31, 2014Publication date: February 5, 2015Applicant: Colorado State University Research FoundationInventors: William S. Compel, Christopher J. Ackerson, On Lo A. Wong
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Patent number: 8304257Abstract: Improved methods for preparing thiolate passivated gold nanoparticles are provided resulting in a narrower size distribution. By alternating oxidation and reduction of the particles, after oxidation, the thiolates may be readily displaced with a different thiol, followed by reduction to prevent further reaction. Proteins can be rigidly bound to the gold nanoparticles by binding an scFv for a target protein to the gold nanoparticles, where the scFv prior or subsequent to binding to the gold nanoparticles may be complexed with the target protein. The protein is rigidly held and its structure readily determined using electron microscopy.Type: GrantFiled: March 8, 2007Date of Patent: November 6, 2012Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Christopher J. Ackerson, Pablo Jadzinsky, Roger D. Kornberg