Abstract: A smaller sized flip dot display utilizes a magnetically actuated pixel that rotates between two orientations. The orientations display two different optical states. A simulated dot matrix design improves the aesthetics and consumer appeal, and also permits a flip dot display capable of producing a positive contrast display image with darker colored “ON” pixels contrasting with brighter background and “OFF” pixels by reducing the visibility of the spacing gap between each rotating pixel and the surrounding background. An interwoven configuration of magnetic actuators with a coil around each arm of a U-shaped core may result in lower power consumption, low production cost, and small size required for use in consumer and small mobile devices such as watches and mobile phones.

Abstract: Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided.

Abstract: The system contains a first planar permanent magnet having a first direction of magnetization and a first opening formed therein. A second planar permanent magnet has a second direction of magnetization and a second opening formed therein. The second opening is axially aligned with the first opening. The direction of magnetization of the first planar permanent magnet opposes the direction of magnetization of the second planar permanent magnet. A plurality of stationary coils are provided, wherein at least one of the stationary coils is located within the first opening and at least one of the stationary coils is located within the second opening. A pair of extension members traverses the first opening and the second opening. A magnetizable slug is integral with each of the extension members.

Abstract: An approach provides machine and a human user interaction in support of dialog flows. A first state file is generated and specifies a plurality of states of a dialog with the human user. The first state file includes logic for transitioning among the states. A second state file is also generated. The second state file specifies a plurality of states of the dialog and includes logic for transitioning among the states, wherein a common process is utilized to interpret the first state file and the second state file. The common process loads one of the state files and determines an appropriate one of a plurality of resources to populate with data associated with the dialog.

Abstract: A system and method for a multiple degrees of freedom motor includes an output shaft. A stator is provided having at least a first lamination stack. Each lamination stack has an interior curved surface. The lamination stacks are disposed adjacent the output shaft. A rotor is fixed to the output shaft and movably supported adjacent the stator with an air gap disposed between the rotor and the stator. The rotor includes at least one magnet disposed thereon. The magnet is movable along the interior curved surface of the lamination stacks in directions defining at least a first degree of freedom. The rotor is biased toward a base position along at least one degree of freedom.

Abstract: An electro-optical system includes a plurality of electromagnetic gain media having a corresponding plurality of apertures. The apertures are disposed in a predetermined spatial distribution. The system further includes at least one refracting surface disposed to intercept energy from the plurality of apertures and a reflecting surface to direct portions of the intercepted energy back through the at least one refracting surface and back toward the plurality of apertures. The return energy is distributed about the plurality of apertures.

Abstract: The system contains a first planar permanent magnet having a first direction of magnetization and a first opening formed therein. A second planar permanent magnet has a second direction of magnetization and a second opening formed therein. The second opening is axially aligned with the first opening. The direction of magnetization of the first planar permanent magnet opposes the direction of magnetization of the second planar permanent magnet. A plurality of stationary coils are provided, wherein at least one of the stationary coils is located within the first opening and at least one of the stationary coils is located within the second opening. A pair of extension members traverses the first opening and the second opening. A magnetizable slug is integral with each of the extension members.

Abstract: A system and method for a multiple degrees of freedom motor includes an output shaft. A stator is provided having at least a first lamination stack. Each lamination stack has an interior curved surface. The lamination stacks are disposed adjacent the output shaft. A rotor is fixed to the output shaft and movably supported adjacent the stator with an air gap disposed between the rotor and the stator. The rotor includes at least one magnet disposed thereon. The magnet is movable along the interior curved surface of the lamination stacks in directions defining at least a first degree of freedom. The rotor is biased toward a base position along at least one degree of freedom.

Abstract: Truncated aggrecanase proteins and nucleotides sequences encoding them as well as processes for producing them are disclosed. Additionally, aggrecanases with amino acid mutations that lead to increased stability and expression levels in comparison with wild-type or native aggrecanases are also disclosed. Aggrecanases of the invention are especially useful for development of compositions for treatment of diseases such as osteoarthritis. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.

Abstract: Truncated aggrecanase proteins and nucleotides sequences encoding them as well as processes for producing them are disclosed. Additionally, aggrecanases with amino acid mutations that lead to increased stability and expression levels in comparison with wild-type or native aggrecanases are also disclosed. Aggrecanases of the invention are especially useful for development of compositions for treatment of diseases such as osteoarthritis. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.

Abstract: Novel aggrecanase proteins and the nucleotide sequences encoding them as well as processes for producing them are disclosed. Methods of identifying and developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.

Abstract: A motor allowing multiple degrees of output freedom includes a stator having an interior surface forming at least a portion of a sphere or curved surface and first and second substantially orthogonally positioned stator coils wound on the interior surface. A rotor is fixed to an output shaft and movably supported adjacent the stator with an air gap disposed between the rotor and the stator. The rotor includes a plurality of magnets disposed thereon and is movable along the interior surface in directions defining at least first and second degrees of freedom. Upon energization of the first stator coil, a first magnetic field is established to urge at least a first one of the magnets and the rotor in a direction of the first degree of freedom and upon energization of the second stator coil, a second magnetic field is established to urge at least a second one of the magnets and the rotor in a direction of the second degree of freedom.

Abstract: An electro-optical system includes a plurality of electromagnetic gain media having a corresponding plurality of apertures. The apertures are disposed in a predetermined spatial distribution. The system further includes a refracting surface disposed to intercept energy from the plurality of apertures and a partially reflecting surface to direct portions of the intercepted energy back toward the plurality of apertures with the directed energy being distributed about the plurality of apertures.

Abstract: A motor allowing multiple degrees of output freedom includes a stator having an interior surface forming at least a portion of a sphere or curved surface and first and second substantially orthogonally positioned stator coils wound on the interior surface. A rotor is fixed to an output shaft and movably supported adjacent the stator with an air gap disposed between the rotor and the stator. The rotor includes a plurality of magnets disposed thereon and is movable along the interior surface in directions defining at least first and second degrees of freedom. Upon energization of the first stator coil, a first magnetic field is established to urge at least a first one of the magnets and the rotor in a direction of the first degree of freedom and upon energization of the second stator coil, a second magnetic field is established to urge at least a second one of the magnets and the rotor in a direction of the second degree of freedom.

Abstract: An electro-optical system includes a plurality of electromagnetic gain media having a corresponding plurality of apertures. The apertures are disposed in a predetermined spatial distribution. The system further includes a refracting surface disposed to intercept energy from the plurality of apertures and a partially reflecting surface to direct portions of the intercepted energy back toward the plurality of apertures with the directed energy being distributed about the plurality of apertures.

Abstract: Truncated aggrecanase proteins and nucleotides sequences encoding them as well as processes for producing them are disclosed. Additionally, aggrecanases with amino acid mutations that lead to increased stability and expression levels in comparison with wild-type or native aggrecanases are also disclosed. Aggrecanases of the invention are especially useful for development of compositions for treatment of diseases such as osteoarthritis. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.

Abstract: Novel aggrecanase proteins and the nucleotide sequences encoding them as well as processes for producing them are disclosed. Methods of identifying and developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.

Abstract: A motor allowing multiple degrees of output freedom is disclosed. The motor includes a stator having an interior surface forming at least a portion of a sphere or curved surface and first and second substantially orthogonally positioned stator coils wound on the interior surface. A rotor is fixed to an output shaft and movably supported adjacent the stator with an air gap disposed between the rotor and the stator. The rotor includes a plurality of magnets disposed thereon and is movable along the interior surface in directions defining at least first and second degrees of freedom. Upon energization of the first stator coil, a first magnetic field is established to force at least a first one of the magnets and the rotor in a direction in the first degree of freedom. Upon energization of the second stator coil, a second magnetic field is established to force at least a second one of the magnets and the rotor in a direction in the second degree of freedom.

Abstract: An electro-optical system includes a plurality of electromagnetic gain media having a corresponding plurality of apertures. The apertures are disposed in a predetermined spatial distribution. The system further includes a refracting surface disposed to intercept energy from the plurality of apertures and a partially reflecting surface to direct portions of the intercepted energy back toward the plurality of apertures with the directed energy being distributed about the plurality of apertures.

Abstract: A motor allowing multiple degrees of output freedom is disclosed. The motor includes a stator having an interior surface forming at least a portion of a sphere or curved surface and first and second substantially orthogonally positioned stator coils wound on the interior surface. A rotor is fixed to an output shaft and movably supported adjacent the stator with an air gap disposed between the rotor and the stator. The rotor includes a plurality of magnets disposed thereon and is movable along the interior surface in directions defining at least first and second degrees of freedom. Upon energization of the first stator coil, a first magnetic field is established to force at least a first one of the magnets and the rotor in a direction in the first degree of freedom. Upon energization of the second stator coil, a second magnetic field is established to force at least a second one of the magnets and the rotor in a direction in the second degree of freedom.