Patents by Inventor Christopher J. Dowd

Christopher J. Dowd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR PREPARING MAMMALIAN CELLS FOR PERFUSION CELL CULTURE
    Publication number: 20240010709
    Abstract: Methods for preparing mammalian cells for perfusion cell culture processes that improve the growth and productivity of the cells are provided. Also provided are cell culture methods that involve subjecting mammalian cells to one or more perfusion procedures, which involve generating a solids phase and a liquid phase with a continuous flow centrifuge, and utilizing at least a portion of the solids phase to sustain, maintain and/or initiate a new cell culture. Perfusion bioreactor systems and components thereof are also provided.
    Type: Application
    Filed: May 25, 2023
    Publication date: January 11, 2024
    Applicant: Genentech, Inc.
    Inventors: Ryan Christopher Hundley, Michael Wilson Laird, Jerome Joseph Bill, Christopher J. Dowd
  • ENHANCED PROTEIN PURIFICATION THROUGH A MODIFIED PROTEIN A ELUTION
    Publication number: 20220324905
    Abstract: The present invention provides methods for purifying a polypeptide comprising a CH2/CH3 region, comprising binding the polypeptide to Protein A and eluting with a pH gradient starting at a low pH.
    Type: Application
    Filed: December 21, 2021
    Publication date: October 13, 2022
    Applicant: Genentech, Inc.
    Inventors: Arick BROWN, Christopher J. DOWD, Asha Nandini-Radhamohan KEBA
  • ENHANCED PROTEIN PURIFICATION THROUGH A MODIFIED PROTEIN A ELUTION
    Publication number: 20220081466
    Abstract: The present invention provides methods for purifying a polypeptide comprising a CH2/CH3 region, comprising binding the polypeptide to Protein A and eluting with a pH gradient starting at a low pH.
    Type: Application
    Filed: May 27, 2021
    Publication date: March 17, 2022
    Applicant: Genentech, Inc.
    Inventors: Arick BROWN, Christopher J. DOWD, Asha Nandini-Radhamohan KEBA
  • Enhanced protein purification through a modified protein A elution
    Patent number: 9428548
    Abstract: The present invention provides methods for purifying a polypeptide comprising a CH2/CH3 region, comprising binding the polypeptide to Protein A and eluting with a pH gradient starting at a low pH.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: August 30, 2016
    Assignee: Genentech, Inc.
    Inventors: Arick Brown, Christopher J. Dowd, Asha Nandini Radhamohan
  • ENHANCED PROTEIN PURIFICATION THROUGH A MODIFIED PROTEIN A ELUTION
    Publication number: 20130041139
    Abstract: The present invention provides methods for purifying a polypeptide comprising a CH2/CH3 region, comprising binding the polypeptide to Protein A and eluting with a pH gradient starting at a low pH.
    Type: Application
    Filed: September 1, 2010
    Publication date: February 14, 2013
    Applicant: Genentech, Inc
    Inventors: Arick Brown, Christopher J. Dowd, Asha Nandini Radhamohan