Patents by Inventor Christopher J. Evans

Christopher J. Evans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gastrin releasing peptide-like peptides
    Patent number: 4613586
    Abstract: Novel peptides having gastrin releasing peptide-like activity having the structures Ala-Pro-Val-Ser-Val-Gly-Gly-Gly-Thr-Val-Leu-Ala-Lys-Met-Tyr-Pro-NH.sub.2 and Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH.sub.2, have been isolated from rat and guinea pig brain extracts and synthesized by a solid phase peptide synthesis methods. The GRP-like peptides are useful as pharmaceuticals to lower body temperature, increase respiratory activity, reduce food intake, stimulate pancreatic hormone release, stimulate pituitary hormone release and suppress thyroid hormone release in mammals.
    Type: Grant
    Filed: April 19, 1984
    Date of Patent: September 23, 1986
    Assignee: Board of Trustees of the Leland Stanford Junior University
    Inventors: Jack D. Barchas, Eckard Weber, Christopher J. Evans, Jaw-Kang Chang, Robin G. Lorenz, Kevin A. Roth
  • Use of Arg-Phe-amide derivatives
    Patent number: 4587233
    Abstract: A method is provided for elevating blood pressure in mammals comprising the step of administering a polypeptide containing the C-terminal residue L-Arg-L-Phe or C-terminal esters or amides thereof.
    Type: Grant
    Filed: November 7, 1983
    Date of Patent: May 6, 1986
    Assignee: Board of Trustees of the Leland Stanford Junior University
    Inventors: Jack D. Barchas, Eckard Weber, Christopher J. Evans, E. T. Wei, J. K. Chang, Ingbert Fuchs, Gabriele Mues
  • Metorphamide--a novel morphine-like peptide
    Patent number: 4490363
    Abstract: A morphine-like amidated opioid octapeptide metorphamide having the struce Try-Gly-Gly-Phe-Met-Arg-Arg-Val-NH.sub.2 has been isolated from bovine caudate nucleus extracts and synthesized by solid phase peptide synthesis methods. Metorphamide is thus far the only natural opioid peptide having a high .mu.-binding activity.
    Type: Grant
    Filed: June 24, 1983
    Date of Patent: December 25, 1984
    Assignee: Board of Trustees of The Leland Stanford Junior University Stanford Univ.
    Inventors: Jack D. Barchas, Eckard Weber, Christopher J. Evans