Abstract: A cardiac information dynamic display system comprises: one or more electrodes configured to record sets of electric potential data representing cardiac activity at a plurality of time intervals; and a cardiac information console, comprising: a signal processor configured to: calculate sets of cardiac activity data at the plurality of time intervals using the recorded sets of electric potential data, wherein the cardiac activity data is associated with surface locations of one or more cardiac chambers; and a user interface module configured to display a series of images, each image comprising: a graphical representation of the cardiac activity. Methods of providing cardiac activity data are also provided.

Abstract: A cardiac information dynamic display system comprises: one or more electrodes configured to record sets of electric potential data representing cardiac activity at a plurality of time intervals; and a cardiac information console, comprising: a signal processor configured to: calculate sets of cardiac activity data at the plurality of time intervals using the recorded sets of electric potential data, wherein the cardiac activity data is associated with surface locations of one or more cardiac chambers; and a user interface module configured to display a series of images, each image comprising: a graphical representation of the cardiac activity. Methods of providing cardiac activity data are also provided.

Abstract: A cardiac information dynamic display system comprises: one or more electrodes configured to record sets of electric potential data representing cardiac activity at a plurality of time intervals; and a cardiac information console, comprising: a signal processor configured to: calculate sets of cardiac activity data at the plurality of time intervals using the recorded sets of electric potential data, wherein the cardiac activity data is associated with surface locations of one or more cardiac chambers; and a user interface module configured to display a series of images, each image comprising: a graphical representation of the cardiac activity. Methods of providing cardiac activity data are also provided.

Abstract: Described herein are method and apparatuses (devices and systems) for determining tissue wetness, and particularly lung wetness. In particular, described herein are apparatuses including patch sensors having a plurality of electrodes one a substrate that includes alignment tabs for aiding in alignment. Also described herein are patch sensors having one or more substrate modifications to enhance local flexibility of the patch. Finally, described herein are apparatuses for determining lung wetness that determine the contour of the body region onto which the patch is applied, e.g., using a diagnostic tool to measure body contour.

Abstract: A medical apparatus for the treatment of one or more sleep disorders such as obstructive sleep apnea in a patient is provided. The medical apparatus has an elongate member with a middle portion, a first fixation element and a second fixation element. The middle portion applies a force to a segment of a patient's airway.

Abstract: Methods and apparatus for delivery of substances or apparatus to target sites located outside blood vessels within the body of a human or animal patient. A vessel wall penetrating catheter is inserted into the vasculature, positioned and oriented within a blood vessel near the target extravascular site and a penetrator is advanced from the catheter so as to penetrate outwardly through the wall of the blood vessel in the direction of the target site. Thereafter, a delivery catheter is passed through a lumen of the penetrator to the target site. A desired substance or apparatus is then delivered to or obtained from the target site. In some applications, the penetrator may be retracted into the vessel wall penetrating catheter and the vessel wall penetrating catheter may be removed, leaving the delivery catheter in place for chronic or continuous delivery of substance(s) to and/or obtaining of information or samples from the target site.

Abstract: A catheter device that is useable to penetrate from a blood vessel in which the catheter device is positioned to a target location comprises a flexible catheter advanceable into the first blood vessel, a tissue penetrator lumen adapted to receive an operative tissue penetrator which is usable to penetrate from the blood vessel to the target location when properly aimed. Further said catheter including an imaging transducer fixedly mounted on or within the catheter body to provide an imaging signal from which an image of the target location can be obtained. The catheter device may include an imageable marker on the catheter to form on the image obtainable from the imaging signal a penetrator path indication that indicates the path that will be followed by the tissue penetrator when the tissue penetrator exits from the catheter. Alternatively, or addition thereto, the imaging transducer may comprise a plurality of imaging elements which are located so that the penetrator path indication can be obtained.

Abstract: Devices and methods for penetrating from a vessel lumen in which a catheter device is positioned to a target location outside of that vessel lumen. A tissue penetrator advances from a catheter positioned within the vessel lumen to the target location when properly aimed. An imaging transducer fixedly mounted on or within the catheter body provides an imaging signal from which an image of the target location can be obtained. An imageable marker may be present on the catheter to form on the image obtainable from the imaging signal to predict the path that will be followed by the tissue penetrator when the tissue penetrator exits from the catheter. Alternatively, or addition thereto, the imaging transducer may comprise a plurality of imaging elements which are located so that the penetrator path indication can be obtained electronically without use of an imageable marker on the catheter.

Abstract: A system for electrospinning a fiber matrix on a tubular member includes at least one nozzle, a tubular member in a spaced relationship to the at least one nozzle, and a fluid source for pressurizing a lumen of the tubular member. An electrical potential is applied between the at least one nozzle and either the tubular member or fluid from the fluid source. The electrical potential draws at least one fiber from the at least one nozzle to the tubular member.

Abstract: A medical apparatus for the treatment of one or more sleep disorders such as obstructive sleep apnea in a patient is provided. The apparatus comprises an elongate member with a middle portion, a first fixation element and a second fixation element. The middle portion applies a force to a segment of a patient's airway.

Abstract: Prosthesis, tools and surgical methods treat joint instability by avoiding loosening over time. A shoulder prosthesis includes a humeral member with a humeral joint surface and a humeral fixation member and a glenoid member comprising a glenoid body with a glenoid joint surface, and a glenoid fixation member attaching the glenoid body to a scapula. The glenoid fixation member may be attached orthogonally to the scapula. A dampener may be included to absorb loads that may loosen one or more components of the prosthesis.

Abstract: Various systems and methods for promoting nerve regeneration are disclosed. The system may include an elongated lead configured to be implanted within a patient's body. The system may also include a plurality of electrodes disposed along the elongated lead and configured to deliver electric stimulation to an area of a patient's body. The plurality of electrodes may comprise at least one transmitting electrode in communication with the controller, wherein the at least one transmitting electrode is configured to transmit an electric signal to one or more other electrodes. The controller may be configured to control operation of the at least one transmitting electrode.

Abstract: The invention provides an implantable apparatus which includes a power supply capable of converting non-electrical energy such as mechanical, chemical, thermal, or nuclear energy into electrical energy. The invention also provides a method of supplying energy to an electrical device within a mammalian body in which the mammal is implanted with an apparatus including a power supply capable of converting non-electrical energy into electrical energy, and non-electrical energy is transcutaneously applied to the apparatus.

Abstract: A septumless implantable access device suitable for delivering a liquid medication to a site remote from the site of implantation is disclosed. The device includes a biocompatible housing having at least one resealable entry port and a cylindrical reservoir in communication with the entry port. An outlet extends from the reservoir to the housing. A filter assembly is disposed within the reservoir for removing particulate material from fluid injected into the entry port. The implantable access device may also include an infusion pump apparatus coupled to the access device.