Patent number: 8876761
Abstract: Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract.
Type:
Grant
Filed:
May 10, 2011
Date of Patent:
November 4, 2014
Assignee:
Ethicon Endo-Surgery, Inc.
Inventors:
Thomas E. Albrecht, Jeffrey L. Aldridge, Sean P. Conlon, Michael S. Cropper, Denzel Z. Herrera-Davis, Daniel F. Dlugos, Jr., Jason L. Harris, Christopher J. Hess, Prasanna Malaviya, Glenda C. Marsh, Mark S. Ortiz, Mark D. Overmyer, Alessandro Pastorelli, Galen C. Robertson, Frederick E. Shelton, IV, Michael J. Stokes, James W. Voegele, Lauren S. Weaner, William B. Weisenburgh, II, Christopher W. Widenhouse, Tamara S. Vetro Widenhouse, James A. Woodard, Jr., David C. Yates, Mark S. Zeiner, Andrew M. Zwolinski
Publication number: 20140155807
Abstract: Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient.
Type:
Application
Filed:
December 9, 2013
Publication date:
June 5, 2014
Applicant:
Ethicon Endo-Surgery, Inc.
Inventors:
Thomas E. Albrecht, Jeffrey L. Aldridge, Sean P. Conlon, Michael S. Cropper, Denzel Z. Herrera-Davis, Daniel F. Dlugos, Jason L. Harris, Christopher J. Hess, Thomas W. Huitema, John W. Hunt, Prasanna Malaviya, Mark S. Ortiz, Mark D. Overmyer, Alessandro Pastorelli, Galen C. Robertson, Frederick E. Shelton, IV, Michael J. Stokes, Foster B. Stulen, James W. Voegele, William B. Weisenburgh, II, Christopher W. Widenhouse, Tamara S. Vetro Widenhouse, James A. Woodard, JR., David C. Yates, Mark S. Zeiner, Andrew M. Zwolinksi