Patents by Inventor Christopher J. Krco

Christopher J. Krco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11136393
    Abstract: Materials and methods for treating cancer, including materials and methods for treating cancer in patients identified as having elevated levels of Bim.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: October 5, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Haidong Dong, Susan M. Harrington, Eugene D. Kwon, Christopher J. Krco, Xin Liu
  • Patent number: 10948480
    Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.
    Type: Grant
    Filed: March 12, 2018
    Date of Patent: March 16, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
  • Publication number: 20190315869
    Abstract: Materials and methods for treating cancer, including materials and methods for treating cancer in patients identified as having elevated levels of Bim.
    Type: Application
    Filed: April 15, 2019
    Publication date: October 17, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Haidong Dong, Susan M. Harrington, Eugene D. Kwon, Christopher J. Krco, Xin Liu
  • Patent number: 10259875
    Abstract: Materials and methods for treating cancer especially in patients identified as having elevated levels of Bim are disclosed. Specifically, the disclosure provides a method for treating a mammal having cancer, the method comprises: (a) identifying said mammal as containing an elevated level of Bim, and (b) administering to said mammal an anti-B7-H1 antibody, an anti-PD-1 antibody, an anti-CD80 antibody, or a fusion protein comprising a portion of PD1 or a portion of CD80, under conditions wherein the interaction of naturally occurring B7-H1 with PD-1 or CD80 in said mammal is reduced after said administering.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: April 16, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Haidong Dong, Susan M. Harrington, Eugene D. Kwon, Christopher J. Krco, Xin Liu
  • Patent number: 10167336
    Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: January 1, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Haidong Dong, Eugene D. Kwon, Svetomir N. Markovic, Christopher J. Krco
  • Publication number: 20180231521
    Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.
    Type: Application
    Filed: March 12, 2018
    Publication date: August 16, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
  • Patent number: 9915646
    Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: March 13, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
  • Publication number: 20160251437
    Abstract: Materials and methods for treating cancer especially in patients identified as having elevated levels of Bim are disclosed. Specifically, the disclosure provides a method for treating a mammal having cancer, the method comprises: (a) identifying said mammal as containing an elevated level of Bim, and (b) administering to said mammal an anti-B7-H1 antibody, an anti-PD-1 antibody, an anti-CD80 antibody, or a fusion protein comprising a portion of PD 1 or a portion of CD80, under conditions wherein the interaction of naturally occurring B7-H1 with PD-1 or CD80 in said mammal is reduced after said administering.
    Type: Application
    Filed: September 3, 2014
    Publication date: September 1, 2016
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Haidong Dong, Susan M. Harrington, Eugene D. Kwon, Christopher J. Krco, Xin Liu
  • Publication number: 20160176967
    Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.
    Type: Application
    Filed: February 26, 2016
    Publication date: June 23, 2016
    Inventors: Haidong Dong, Eugene D. Kwon, Svetomir N. Markovic, Christopher J. Krco
  • Publication number: 20160131638
    Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.
    Type: Application
    Filed: December 15, 2015
    Publication date: May 12, 2016
    Inventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
  • Patent number: 9302005
    Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: April 5, 2016
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Haidong Dong, Eugene D. Kwon, Svetomir N. Markovic, Christopher J. Krco
  • Patent number: 9243033
    Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: January 26, 2016
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
  • Publication number: 20140271674
    Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.
    Type: Application
    Filed: February 27, 2014
    Publication date: September 18, 2014
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Haidong Dong, Eugene D. Kwon, Svetomir N. Markovic, Christopher J. Krco
  • Publication number: 20140212443
    Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.
    Type: Application
    Filed: June 13, 2013
    Publication date: July 31, 2014
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
  • Patent number: 8486412
    Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.
    Type: Grant
    Filed: June 1, 2007
    Date of Patent: July 16, 2013
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
  • Publication number: 20100272741
    Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.
    Type: Application
    Filed: June 1, 2007
    Publication date: October 28, 2010
    Inventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco