Patents by Inventor Christopher J. Krco
Christopher J. Krco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11136393Abstract: Materials and methods for treating cancer, including materials and methods for treating cancer in patients identified as having elevated levels of Bim.Type: GrantFiled: April 15, 2019Date of Patent: October 5, 2021Assignee: Mayo Foundation for Medical Education and ResearchInventors: Haidong Dong, Susan M. Harrington, Eugene D. Kwon, Christopher J. Krco, Xin Liu
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Patent number: 10948480Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.Type: GrantFiled: March 12, 2018Date of Patent: March 16, 2021Assignee: Mayo Foundation for Medical Education and ResearchInventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
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Publication number: 20190315869Abstract: Materials and methods for treating cancer, including materials and methods for treating cancer in patients identified as having elevated levels of Bim.Type: ApplicationFiled: April 15, 2019Publication date: October 17, 2019Applicant: Mayo Foundation for Medical Education and ResearchInventors: Haidong Dong, Susan M. Harrington, Eugene D. Kwon, Christopher J. Krco, Xin Liu
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Patent number: 10259875Abstract: Materials and methods for treating cancer especially in patients identified as having elevated levels of Bim are disclosed. Specifically, the disclosure provides a method for treating a mammal having cancer, the method comprises: (a) identifying said mammal as containing an elevated level of Bim, and (b) administering to said mammal an anti-B7-H1 antibody, an anti-PD-1 antibody, an anti-CD80 antibody, or a fusion protein comprising a portion of PD1 or a portion of CD80, under conditions wherein the interaction of naturally occurring B7-H1 with PD-1 or CD80 in said mammal is reduced after said administering.Type: GrantFiled: September 3, 2014Date of Patent: April 16, 2019Assignee: Mayo Foundation for Medical Education and ResearchInventors: Haidong Dong, Susan M. Harrington, Eugene D. Kwon, Christopher J. Krco, Xin Liu
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Patent number: 10167336Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.Type: GrantFiled: February 26, 2016Date of Patent: January 1, 2019Assignee: Mayo Foundation for Medical Education and ResearchInventors: Haidong Dong, Eugene D. Kwon, Svetomir N. Markovic, Christopher J. Krco
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Publication number: 20180231521Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.Type: ApplicationFiled: March 12, 2018Publication date: August 16, 2018Applicant: Mayo Foundation for Medical Education and ResearchInventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
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Patent number: 9915646Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.Type: GrantFiled: December 15, 2015Date of Patent: March 13, 2018Assignee: Mayo Foundation for Medical Education and ResearchInventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
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Publication number: 20160251437Abstract: Materials and methods for treating cancer especially in patients identified as having elevated levels of Bim are disclosed. Specifically, the disclosure provides a method for treating a mammal having cancer, the method comprises: (a) identifying said mammal as containing an elevated level of Bim, and (b) administering to said mammal an anti-B7-H1 antibody, an anti-PD-1 antibody, an anti-CD80 antibody, or a fusion protein comprising a portion of PD 1 or a portion of CD80, under conditions wherein the interaction of naturally occurring B7-H1 with PD-1 or CD80 in said mammal is reduced after said administering.Type: ApplicationFiled: September 3, 2014Publication date: September 1, 2016Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHInventors: Haidong Dong, Susan M. Harrington, Eugene D. Kwon, Christopher J. Krco, Xin Liu
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Publication number: 20160176967Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.Type: ApplicationFiled: February 26, 2016Publication date: June 23, 2016Inventors: Haidong Dong, Eugene D. Kwon, Svetomir N. Markovic, Christopher J. Krco
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Publication number: 20160131638Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.Type: ApplicationFiled: December 15, 2015Publication date: May 12, 2016Inventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
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Patent number: 9302005Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.Type: GrantFiled: February 27, 2014Date of Patent: April 5, 2016Assignee: Mayo Foundation for Medical Education and ResearchInventors: Haidong Dong, Eugene D. Kwon, Svetomir N. Markovic, Christopher J. Krco
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Patent number: 9243033Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.Type: GrantFiled: June 13, 2013Date of Patent: January 26, 2016Assignee: Mayo Foundation for Medical Education and ResearchInventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
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Publication number: 20140271674Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.Type: ApplicationFiled: February 27, 2014Publication date: September 18, 2014Applicant: Mayo Foundation for Medical Education and ResearchInventors: Haidong Dong, Eugene D. Kwon, Svetomir N. Markovic, Christopher J. Krco
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Publication number: 20140212443Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.Type: ApplicationFiled: June 13, 2013Publication date: July 31, 2014Applicant: Mayo Foundation for Medical Education and ResearchInventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
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Patent number: 8486412Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.Type: GrantFiled: June 1, 2007Date of Patent: July 16, 2013Assignee: Mayo Foundation for Medical Education and ResearchInventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco
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Publication number: 20100272741Abstract: This document provides methods and materials related to assessing immunity to folate receptors. For example, methods and materials for assessing FR? immunity in a mammal are provided. This document also provides methods and materials related to stimulating immunity to folate receptors.Type: ApplicationFiled: June 1, 2007Publication date: October 28, 2010Inventors: Keith L. Knutson, Lynn C. Hartmann, Kimberly R. Kalli, Christopher J. Krco