Patents by Inventor Christopher J. Lawson

Christopher J. Lawson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KRas G12D inhibitors
    Patent number: 11964989
    Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 20, 2022
    Date of Patent: April 23, 2024
    Assignees: Mirati Therapeutics, Inc., Array BioPharma Inc.
    Inventors: Xiaolun Wang, Aaron Craig Burns, James Gail Christensen, John Michael Ketcham, John David Lawson, Matthew Arnold Marx, Christopher Ronald Smith, Shelley Allen, James F. Blake, Mark Joseph Chicarelli, Joshua Ryan Dahlke, Donghua Dai, Jay Bradford Fell, John Peter Fischer, Macedonio J. Mejia, Brad Newhouse, Phong Nguyen, Jacob Matthew O'Leary, Spencer Pajk, Martha E. Rodriguez, Pavel Savechenkov, Tony P. Tang, Guy P.A. Vigers, Qian Zhao, Dean Russell Kahn, John Gaudino, Michael Christopher Hilton
  • Suspensions and gels of indican and their uses
    Patent number: 4372785
    Abstract: Indican, a polysaccharide comprising (1.fwdarw.3) glucose, (1.fwdarw.4) mannose, (1.fwdarw.4) rhamnose and (1.fwdarw.3 or 4) -0-(1-carboxyethyl)rhamnose units in a molar ratio of about 2:1:1-2:1 respectively; containing 12-15% by weight acetyl units [.alpha.].sub.D.sup.20 about -61.degree.; having principle absorption bands in the infra red band at 3390, 1735, 1615, 1375, 1250 and 1050 cm.sup.-1 ; a solubility of at least 1% by weight in methanol and in ethylene glycol, and an inherent viscosity of about 33.5 dl/g. has useful thixotropic properties and provides a method of modifying the viscosity of a liquid by incorporating indican therein. The liquid may be aqueous or organic solvent-based. Thickened and stabilised products are also provided.
    Type: Grant
    Filed: March 3, 1982
    Date of Patent: February 8, 1983
    Assignee: Talres Development (N.A.) N.V.
    Inventors: Christopher J. Lawson, Kenneth C. Symes
  • Indican and suspensions and gels thereof and their uses
    Patent number: 4338432
    Abstract: Indican, a polysaccharide comprising (1.fwdarw.3) glucose, (1.fwdarw.4) mannose, (1.fwdarw.4) rhamnose and (1.fwdarw.3 or 4) -0-(1-carboxyethyl)-rhamnose units in a molar ratio of about 2:1:1-2:1 respectively; containing 12-15% by weight acetyl units; [.alpha.]D.sup.20 about -61.degree.; having principle absorption bands in the infra red band at 3390, 1735, 1615, 1375, 1250 and 1050 cm.sup.-1 ; a solubility of at least 1% by weight in methanol and in ethylene glycol, and an inherent viscosity of about 33.5 dl/g. has useful thixotropic properties and provides a method of modifying the viscosity of a liquid by incorporating indican therein. The liquid may be aqueous or organic solvent-based. Thickened and stabilized products and a method of preparing indican by culture of an indican-producing microorganism are also provided.
    Type: Grant
    Filed: February 29, 1980
    Date of Patent: July 6, 1982
    Assignee: Talres Development (N.A.) N.V.
    Inventors: Christopher J. Lawson, Kenneth C. Symes
  • Process for the preparation of polysaccharide 9
    Patent number: 4298725
    Abstract: A polysaccharide processing useful flow and gel-forming properties is prepared by cultivation of Pseudomonas sp NCIB 11264 (ATCC 31260). The polysaccharide, which readily can be produced in up to 75% yield by continuous culture, possesses properties which are similar to those of xanthan and other gums.
    Type: Grant
    Filed: February 1, 1978
    Date of Patent: November 3, 1981
    Assignee: Tate & Lyle Limited
    Inventors: Alan G. Williams, Christopher J. Lawson, Julian W. T. Wimpenny