Abstract: Applications for risk evaluation and mitigation strategy (REMS) are disclosed herein. Such applications may execute on devices operated by healthcare professionals, patients, pharmaceutical companies, pharmacies, third parties and other parties. One or more of such devices may be mobile devices, thereby allowing information to be presented and obtained at a variety of times and locations. One or more different features may be made available to each of such parties as necessary to assist in their desired scope of interaction with a REMS program. Applications on client devices may communicate with one or more servers to send and receive information associated with REMS related features.

Abstract: Methods for delivering a drug to a patient in need of the drug, while restricting access to the drug by patients for whom the drug may be contraindicated are disclosed. The methods are of the type in which prescriptions for the drug are filled by a pharmacy only after a computer readable storage medium has been consulted to retrieve a prescription approval code. Embodiments are provided wherein the patients are assigned to risk groups based upon the risk that taking the drug will lead to an adverse side effect, and certain additional information, such as periodic surveys and diagnostic tests probative of the ongoing risk of the side effect developing are obtained before prescriptions for the drug are approved.