Patents by Inventor Christopher J. Paige

Christopher J. Paige has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION CYTOKINES FOR METHODS AND COMPOSITIONS FOR TREATING CANCER
    Publication number: 20230279424
    Abstract: Methods and compositions of whole cell vaccines for delivering immune modulatory molecules IL-12 and at least one of IL-21 and/or IL-18 to result in a therapeutic effect are disclosed. The methods and compositions use stably integrating lentiviral delivery systems. The methods are useful for therapeutically and prophylactically treating cancer such as leukemia.
    Type: Application
    Filed: May 26, 2021
    Publication date: September 7, 2023
    Inventor: Christopher J. Paige
  • IL-12 IMMUNOTHERAPY FOR CANCER
    Publication number: 20200038457
    Abstract: Compositions and methods for delivering immune modulatory molecules to result in a therapeutic effect are disclosed. The compositions and methods use stably integrating lentiviral delivery systems. The methods are useful for therapeutically and prophylactically treating cancer such as leukemia.
    Type: Application
    Filed: March 19, 2019
    Publication date: February 6, 2020
    Inventors: Jeffrey A. MEDIN, Christopher J. PAIGE
  • IL-12 immunotherapy for cancer
    Patent number: 10258653
    Abstract: Compositions and methods for delivering immune modulatory molecules to result in a therapeutic effect are disclosed. The compositions and methods use stably integrating lentiviral delivery systems. The methods are useful for therapeutically and prophylactically treating cancer such as leukemia.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: April 16, 2019
    Assignee: University Health Network
    Inventors: Jeffrey A. Medin, Christopher J. Paige
  • IL-12 immunotherapy for cancer
    Patent number: 10022405
    Abstract: Compositions and methods far delivering immune modulatory molecules to result in a therapeutic effect are disclosed. The compositions and methods use stably integrating lentiviral delivery systems. The methods are useful for therapeutically and prophylactically treating cancer such as leukemia.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: July 17, 2018
    Assignee: University Health Network
    Inventors: Jeffrey A. Medin, Christopher J. Paige
  • DRUG COMPLEXES COMPRISING ALPHA-FETOPROTEIN
    Publication number: 20180015066
    Abstract: Compositions which comprise a hydro-phobic taxane such as paclitaxel are produced by non-covalent complexing between the taxane and alpha-fetoprotein c at a ratio of about 4 moles of taxane per mole of AFP. The complexes are water soluble and suitable for injection. Uses of the compositions for treating a subject presenting with an AFP receptor positive and taxane responsive ease cell are also disclosed.
    Type: Application
    Filed: January 26, 2016
    Publication date: January 18, 2018
    Inventors: Lakshmi P. Kotra, Christopher J. Paige, Angelica M. Bello, Igor Sherman
  • IL-12 IMMUNOTHERAPY FOR CANCER
    Publication number: 20170136072
    Abstract: Compositions and methods far delivering immune modulatory molecules to result in a therapeutic effect are disclosed. The compositions and methods use stably integrating lentiviral delivery systems. The methods are useful for therapeutically and prophylactically treating cancer such as leukemia.
    Type: Application
    Filed: November 22, 2016
    Publication date: May 18, 2017
    Inventors: Jeffrey A. MEDIN, Christopher J. PAIGE
  • IL-12 Immunotherapy for Cancer
    Publication number: 20160130317
    Abstract: Compositions and methods for delivering immune modulatory molecules to result in a therapeutic effect are disclosed. The compositions and methods use stably integrating lentiviral delivery systems. The methods are useful for therapeutically and prophylactically treating cancer such as leukemia.
    Type: Application
    Filed: December 30, 2015
    Publication date: May 12, 2016
    Inventors: JEFFREY A. MEDIN, CHRISTOPHER J. PAIGE
  • IL-12 IMMUNOTHERAPY FOR CANCER
    Publication number: 20140370039
    Abstract: Compositions and methods for delivering immune modulatory molecules to result in a therapeutic effect are disclosed. The compositions and methods use stably integrating lentiviral delivery systems. The methods are useful for therapeutically and prophylactically treating cancer such as leukemia.
    Type: Application
    Filed: May 21, 2014
    Publication date: December 18, 2014
    Applicant: University Health Network
    Inventors: Jeffrey A. Medin, Christopher J. Paige
  • IL-12 immunotherapy for cancer
    Patent number: 8765462
    Abstract: Compositions and methods for delivering immune modulatory molecules to result in a therapeutic effect are disclosed. The compositions and methods use stably integrating lentiviral delivery systems. The methods are useful for therapeutically and prophylactically treating cancer such as leukemia.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: July 1, 2014
    Assignee: University Health Network
    Inventors: Jeffrey A. Medin, Christopher J. Paige
  • IL-12 IMMUNOTHERAPY FOR CANCER
    Publication number: 20100291043
    Abstract: Compositions and methods for delivering immune modulatory molecules to result in a therapeutic effect are disclosed. The compositions and methods use stably integrating lentiviral delivery systems. The methods are useful for therapeutically and prophylactically treating cancer such as leukemia.
    Type: Application
    Filed: May 5, 2008
    Publication date: November 18, 2010
    Applicant: UNIVERSITY HEALTH NETWORK
    Inventors: Jeffrey A. Medin, Christopher J. Paige
  • Pyrimidine Derivatives As Anticancer Agents
    Publication number: 20100056468
    Abstract: The present invention includes methods of treating or preventing cancer by administering an effective amount of 6-substituted pyrimidine derivatives of the Formula I to a subject need thereof:
    Type: Application
    Filed: January 8, 2008
    Publication date: March 4, 2010
    Applicant: University Health Network
    Inventors: Lakshmi P. Kotra, Emil F. Pai, Christopher J. Paige, Angelica M. Bello