Abstract: Suture passers and methods of use. Described herein are suture passers preloaded with suture, including cartridges that couple to a suture passer to form a loaded suture passer that are configured to prevent a length of suture (e.g., already-passed suture) from re-entering the channel of the suture passer jaw and getting recaptured and/or entangled by the tissue penetrator. In particular, described herein are preloaded and automatically re-loading suture passers that are adapted to include a gate, guide or shield on one of the jaws of the suture passer, and methods of operating such suture passers for surgical use including repairing tissue.

Abstract: An airfoil for a gas turbine engine according to an example of the present disclosure includes an airfoil section extending in a radial direction from a root section to a tip portion. The airfoil section has an external wall and an internal wall. The airfoil section establishes an internal cooling arrangement including a first cooling passage having a first section and a tip flag section. The tip flag section extends in the chordwise direction along the tip portion from the first section. The first section includes a plurality of branched paths established by at least one turning vane.

Abstract: An airfoil core includes a first core portion that has a hybrid skin core, a tip flag core, and a trailing edge core. A second core portion has a serpentine core and a leading edge core.

Abstract: Aspects of the disclosure are directed to a seal comprising: a shoe, and at least two beams coupled to the shoe, where a first width associated with the beams exceeds a second width associated with the shoe in a reference direction. Aspects of the disclosure are directed to an engine comprising: a compressor section, a turbine section, and a floating, non-contact seal that includes: a shoe, and at least two beams coupled to the shoe, where the beams extend past an edge of a flowpath surface associated with the shoe in a reference direction.

Abstract: An airfoil core includes a first core portion that has a hybrid skin core, a tip flag core, and a trailing edge core. A second core portion has a serpentine core and a leading edge core.

Abstract: A method of forming an airfoil, includes forming a hybrid skin core, a tip flag core, and a trailing edge core. The hybrid skin core, tip flag core, and trailing edge core are connected to form a first core portion. A leading edge core and a serpentine core are formed. The first core portion, the leading edge core, and the serpentine core are assembled together to form an airfoil core. An airfoil is formed around the airfoil core.

Abstract: According to certain examples, a head-mounted apparatus includes a safety eyewear component and an optical display coupled to the safety eyewear component. The safety eyewear component is configured to be worn of a head of an operator and to block transmission of a laser light therethrough. The optical display is configured to receive data associated with the laser light and to display a visual representation of the laser light in a field of view of the operator. In other examples, an apparatus includes a display, a sensor, at least one processor and at least one memory storing computer-readable instructions that, when executed by the at least one processor, cause the apparatus to receive, from the sensor, data associated with a laser light, process the data, and provide an image to the display, such as a representation of the laser light.

Abstract: A non-contact seal assembly includes a plurality of seal shoes, a seal base and a plurality of spring elements. A first of the spring elements includes a first mount, a second mount and a spring beam. The spring beam extends a length longitudinally along a centerline from the first mount to the second mount. The spring beam includes opposing first and second surfaces. The first surface is disposed a first distance from the centerline, and the second surface is disposed a second distance from the centerline. The first distance and the second distance change as the spring beam extends longitudinally along the centerline to provide at least a portion of the spring beam with a tapered geometry. The portion of the spring beam has a longitudinal length that is at least about five percent of the length of the spring beam.

Abstract: A method of forming an airfoil, includes forming a hybrid skin core, a tip flag core, and a trailing edge core. The hybrid skin core, tip flag core, and trailing edge core are connected to form a first core portion. A leading edge core and a serpentine core are formed. The first core portion, the leading edge core, and the serpentine core are assembled together to form an airfoil core. An airfoil is formed around the airfoil core.

Abstract: Aspects of the disclosure are directed to a seal comprising: a shoe, and at least two beams coupled to the shoe, where a first width associated with the beams exceeds a second width associated with the shoe in a reference direction. Aspects of the disclosure are directed to an engine comprising: a compressor section, a turbine section, and a floating, non-contact seal that includes: a shoe, and at least two beams coupled to the shoe, where the beams extend past an edge of a flowpath surface associated with the shoe in a reference direction.

Abstract: Aspects of the disclosure are directed to a floating, non-contact seal comprising: a shoe, and at least three beams, each beam having a first axial end and a second axial end, where the first axial ends are coupled to the shoe and the second axial ends are coupled to a ring structure. Aspects of the disclosure are directed to an engine comprising: a first structure, a second structure configured to rotate relative to the first structure, and a floating, non-contact seal that interfaces the first structure and the second structure, where the seal includes: a shoe, and at least three beams, where each beam has a first axial end and a second axial end, where the first axial ends are coupled to the shoe and the second axial ends are coupled to a ring structure.

Abstract: Aspects of the disclosure are directed to a seal comprising: a shoe, and at least two beams coupled to the shoe, where a first width associated with the beams exceeds a second width associated with the shoe in a reference direction. Aspects of the disclosure are directed to an engine comprising: a compressor section, a turbine section, and a floating, non-contact seal that includes: a shoe, and at least two beams coupled to the shoe, where the beams extend past an edge of a flowpath surface associated with the shoe in a reference direction.

Abstract: A seal assembly includes an annular base, a spring, a shoe, a first channel, a seal cover, and a seal. The spring includes a beam and is connected to the annular base. The shoe is disposed radially inward of the annular base and connected to the spring. The shoe includes an upstream portion, a downstream portion, and a lip connected to and extending radially outward from the upstream portion of the shoe. The spring extends from the annular base to the shoe. The first channel is positioned between the shoe and the beam of the spring. The seal is disposed between the seal cover and the shoe such that a downstream face of the seal is in contact with an upstream face of the shoe.

Abstract: An assembly is provided for rotational equipment with an axial centerline. This assembly includes a primary seal device, a ring structure and a secondary seal device. The primary seal device is configured as a hydrostatic non-contact seal device. The primary seal device includes a plurality of seal shoes and a seal base. The seal shoes are arranged circumferentially about the axial centerline in an annular array. The seal base circumscribes the annular array of the seal shoes. The ring structure is axially engaged with the seal base. The secondary seal device is mounted with the ring structure. The secondary seal device includes a seal ring body and an alignment tab. The seal ring body is configured to substantially seal an annular gap between the ring structure and the seal base. The alignment tab projects out from the seal ring body and into an aperture in the ring structure. The alignment tab is adapted to substantially rotationally locate and/or fix the secondary seal device to the ring structure.

Abstract: A non-contact seal assembly is provided. This assembly includes a plurality of seal shoes, a seal base and a plurality of spring elements. The seal shoes are arranged about a centerline in an annular array. The seal shoes include a first seal shoe extending axially along the centerline between a first shoe end and a second shoe end. An aperture may extend partially axially into the first seal shoe from the first shoe end and laterally within the first seal shoe. The seal base circumscribes the annular array of the seal shoes. Each of the spring elements is radially between and connects a respective one of the seal shoes with the seal base.

Abstract: A non-contact seal assembly includes a plurality of seal shoes, a seal base and a plurality of spring elements. A first of the spring elements includes a first mount, a second mount and a spring beam. The spring beam extends a length longitudinally along a centerline from the first mount to the second mount. The spring beam includes opposing first and second surfaces. The first surface is disposed a first distance from the centerline, and the second surface is disposed a second distance from the centerline. The first distance and the second distance change as the spring beam extends longitudinally along the centerline to provide at least a portion of the spring beam with a tapered geometry. The portion of the spring beam has a longitudinal length that is at least about five percent of the length of the spring beam.

Abstract: A non-contact seal assembly is provided. This assembly includes a plurality of seal shoes, a seal base and a plurality of spring elements. The seal shoes are arranged about a centerline in an annular array. The seal shoes include a first seal shoe extending axially along the centerline between a first shoe end and a second shoe end. An aperture may extend partially axially into the first seal shoe from the first shoe end and laterally within the first seal shoe. The seal base circumscribes the annular array of the seal shoes. Each of the spring elements is radially between and connects a respective one of the seal shoes with the seal base.

Abstract: The present invention relates to a method of aiding in the prognosis of a subject with oesophageal and/or gastro-oesophageal junctional (GOJ) adenocarcinoma, the method comprising the steps of: (a) providing a sample from the subject, (b) determining the expression level of biomarkers TRIM44 and SIRT2 in said sample, and either (i) determining the expression level of biomarker PAPPS2 in said sample; or (ii) determining the expression level of biomarkers WT1 and EGFR in said sample; (c) comparing the expression level of each of said biomarkers to a corresponding reference standard, (d) determining the biomarkers of (b) whose expression is dysregulated compared to the reference standard, (e) inferring from the dysregulated biomarkers identified in (d) the prognosis of 5-year survival, wherein the greater the number of said biomarkers which are dysregulated, the greater the reduction in prognosis of 5-year survival. The invention also relates to kits, uses and devices.

Abstract: A non-contact seal assembly includes a plurality of seal shoes, a seal base and a plurality of spring elements. A first of the spring elements includes a first mount, a second mount and a spring beam. The spring beam extends a length longitudinally along a centerline from the first mount to the second mount. The spring beam includes opposing first and second surfaces. The first surface is disposed a first distance from the centerline, and the second surface is disposed a second distance from the centerline. The first distance and the second distance change as the spring beam extends longitudinally along the centerline to provide at least a portion of the spring beam with a tapered geometry. The portion of the spring beam has a longitudinal length that is at least about five percent of the length of the spring beam.

Abstract: A non-contact seal assembly is provided. This assembly includes a plurality of seal shoes, a seal base and a plurality of spring elements. The seal shoes are arranged about a centerline in an annular array. The seal shoes include a first seal shoe extending axially along the centerline between a first shoe end and a second shoe end. An aperture may extend partially axially into the first seal shoe from the first shoe end and laterally within the first seal shoe. The seal base circumscribes the annular array of the seal shoes. Each of the spring elements is radially between and connects a respective one of the seal shoes with the seal base.