Patents by Inventor Christopher James Nicolai

Christopher James Nicolai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Materials and methods for producing improved lentiviral vector particles
    Patent number: 10993999
    Abstract: Materials and methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein are provided.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: May 4, 2021
    Assignee: Immune DesignCorp.
    Inventors: Christopher James Nicolai, Semih U. Tareen
  • MATERIALS AND METHODS FOR PRODUCING IMPROVED LENTIVIRAL VECTOR PARTICLES
    Publication number: 20200030423
    Abstract: Materials and methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein are provided.
    Type: Application
    Filed: July 16, 2019
    Publication date: January 30, 2020
    Inventors: Christopher James Nicolai, Semih U. Tareen
  • Materials and methods for producing improved lentiviral vector particles
    Patent number: 10391157
    Abstract: Materials and methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein are provided.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: August 27, 2019
    Assignee: IMMUNE DESIGN CORP.
    Inventors: Christopher James Nicolai, Semih U. Tareen
  • MATERIALS AND METHODS FOR PRODUCING IMPROVED LENTIVIRAL VECTOR PARTICLES
    Publication number: 20180055921
    Abstract: Materials and methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein are provided.
    Type: Application
    Filed: June 2, 2017
    Publication date: March 1, 2018
    Applicant: IMMUNE DESIGN CORP
    Inventors: Christopher James Nicolai, Semih U. Tareen
  • Materials and methods for producing improved lentiviral vector particles
    Patent number: 9713635
    Abstract: Materials and methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein are provided.
    Type: Grant
    Filed: March 29, 2013
    Date of Patent: July 25, 2017
    Assignee: IMMUNE DESIGN CORP.
    Inventors: Christopher James Nicolai, Semih U. Tareen
  • MATERIALS AND METHODS FOR PRODUCING IMPROVED LENTIVIRAL VECTOR PARTICLES
    Publication number: 20150050307
    Abstract: Materials and methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein are provided.
    Type: Application
    Filed: March 29, 2013
    Publication date: February 19, 2015
    Inventors: Christopher James Nicolai, Semih U. Tareen
  • Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein
    Patent number: 8323662
    Abstract: Materials and methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein are provided. More specifically, methods for generating such materials include culturing in a culture medium including kifunensine a virus packaging cell with a lentiviral vector genome including a polynucleotide encoding an exogenous antigen, a polynucleotide encoding a Sindbis E2 glycoprotein that preferentially binds dendritic cells expressing DC-SIGN, and a polynucleotide encoding a Vpx protein or a Vpr protein that retains SAMHD1-inhibiting activity, followed by isolating a pseudotyped lentiviral vector particle that preferentially binds dendritic cells expressing DC-SIGN.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: December 4, 2012
    Assignee: Immune Design Corp.
    Inventors: Christopher James Nicolai, Semih Ullah Tareen