Abstract: Support structures are used in certain additive fabrication processes to permit fabrication of a greater range of object geometries. For additive fabrication processes with materials that are subsequently sintered into a final part, an interface layer is formed between the object and support in order to inhibit bonding between adjacent surfaces of the support structure and the object during sintering.

Abstract: A mask system for delivery of respiratory therapy to a patient includes a nares portion and a mouth portion and an inlet conduit connected to at least one of the nares portion and the mouth portion to deliver the pressurized, breathable gas. The mask system is adapted to selectively utilize the nares portion and/or the mouth portion in a first mode utilizing both the nares portion and the mouth portion, and in a second mode utilizing the nares portion and not utilizing the mouth portion.

Abstract: A retractable purging mechanism is preferably comprised of a bracket that is connectable to a 3D printer. An actuatable shaft is secured to the bracket and the shaft engages a rocker arm, which in turn engages a collecting tray and moves the collecting tray from a first position to a second position. The collecting tray is adapted to receive a material that is discarded when, for example, a different print colour is used in 3D printing. A sweeper is also provided, the sweeper connected to the collecting tray to remove the material from the collecting tray.

Abstract: The present disclosure provides a retractable purging mechanism preferably comprised of a bracket that is connectable to a 3D printer. An actuatable shaft is secured to the bracket and the shaft engages a rocker arm, which in turn engages a collecting tray and moves the collecting tray from a first position to a second position. The collecting tray is adapted to receive a material that is discarded when, for example, a different print colour is used in 3D printing. A sweeper is also provided, the sweeper connected to the collecting tray to remove the material from the collecting tray.

Abstract: An automatic tool changing system and method for printing functional three-dimensional (3D) object is disclosed. The system is preferably comprised of an end-effector moveable about the X, Y and Z-axis, the end-effector connecting to various functional heads by means of a dovetail joint. Each functional head is responsible for a different type of functional printing as required by the 3D object, and each functional head is positioned on a docking station for ease of access by the end-effector. The method to print a functional 3D object is comprised of printing a first portion of the object, using the various functional heads to print functional components of the object, and then finishing printing the 3D object.

Abstract: The present disclosure provides antibodies and antigen binding fragments thereof including, but not limited to, monoclonal antibodies that specifically bind to human programmed death ligand 2 (PD-L2). The invention further provides nucleic acids encoding the antibodies and antigen binding fragments of the invention and host cells transformed therewith. The antibodies and antigen binding proteins of the invention are useful in methods for the immunohistochemical detection of human PD-L2 expression in tissue samples.

Abstract: The present disclosure provides antibodies and antigen binding fragments thereof including, but not limited to, monoclonal antibodies that specifically bind to human programmed death ligand 2 (PD-L2). The invention further provides nucleic acids encoding the antibodies and antigen binding fragments of the invention and host cells transformed therewith. The antibodies and antigen binding proteins of the invention are useful in methods for the immunohistochemical detection of human PD-L2 expression in tissue samples.