Patents by Inventor Christopher John VAVRICKA JR.

Christopher John VAVRICKA JR. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECOMBINANT HOST CELL FOR PRODUCING BENZYLISOQUINOLINE ALKALOID (BIA) AND NOVEL METHOD FOR PRODUCING BENZYLISOQUINOLINE ALKALOID (BIA)
    Publication number: 20210395717
    Abstract: The purpose of the present invention is to provide a recombinant host cell which is capable of efficiently and easily producing a benzylisoquinoline alkaloid (BIA), in particular, tetrahydropapaveroline, 3-hydroxycoclaurine, 3-hydroxy-N-methylcoclaurine and/or reticuline, and a method for efficiently and easily producing these BIAs using the host cell. The present invention pertains to a recombinant host cell for producing a benzylisoquinoline alkaloid (BIA), in particular, tetrahydropapaveroline (THP), 3-hydroxycoclaurine, 3-hydroxy-N-methylcoclaurine and/or reticuline, in which a wild-type aromatic aldehyde synthase (AAS) or a mutant thereof and a wild-type aromatic amino acid decarboxylase (AAAD) or a mutant thereof are expressed.
    Type: Application
    Filed: October 30, 2019
    Publication date: December 23, 2021
    Applicant: NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY
    Inventors: Christopher John VAVRICKA JR., Tomohisa HASUNUMA, Michihiro ARAKI, Akihiko KONDO