Abstract: The present invention relates to pyrazine derivatives according to the general formula (I) and pharmaceutically acceptable salts thereof and their use as pharmaceutical compounds as well as the use of these compounds for the preparation of a pharmaceutical composition for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases, stroke and especially for the treatment of herpesviral induced infections, including opportunistic infections as well as infections and diseases caused by human cytomegalovirus (HCMV).

Abstract: A nontoxic fuel cell engine coolant which has an electrical resistivity of greater than 250 kOhm-cm, a boiling point of greater than 90° C., a freezing point of less than ?40° C., a thermal conductivity of greater than 0.4 W/m-k, a viscosity of less than 1 cPs at 80° C., a viscosity of less than 6 cPs at 0° C., a heat capacity of greater than 3 kJ/kg-K, and which is compatible with current cooling system materials.

Abstract: An information handling system includes a processor with multiple hardware units that generate program application load, store, and I/O interface requests to system busses within the information handling system. The processor includes a resource allocation identifier (RAID) that links the processor hardware unit initiating a system bus request with a specific resource allocation group. The resource allocation group assigns a specific bandwidth allocation rate to the initiating processor. When a load, store, or I/O interface bus request reaches the I/O bus for execution, the resource allocation manager restricts the amount of bandwidth associated with each I/O request by assigning discrete amounts of bandwidth to each successive I/O requester. Successive stages of the instruction pipeline in the hardware unit contain the resource allocation identifiers (RAID) linked to the specific load, store, or I/O instruction.

Abstract: A multi-regime continuously variable ratio transmission system has coaxial system input and output shafts (16, 24), a continously variable ratio transmission unit (V) connected coaxially to the system input shaft (16) and having a coaxial variator output shaft (18) and a mixing epicyclic gear train (E1) having an input sun gear (S1) drivably connected to the variator ouput shaft (18), a planet carrier (C1) drivably connected to the system input shaft (16) and a planet gear (P1) mounted on the planet carrier ((C1). The planet gear (P1) drives a first intermediate output shaft (22) arranged coaxially with the system input shaft (16) and selectively connectable to the system output shaft via a first clutch (H) in high-regime operation of the transmission. The planet gear (P1) also provides the input for a second epicyclic gear train (E2) having an output (C2) which is selectively connectable to the system output shaft via a braking element (L) for low-regime operation of the transmission.

Abstract: The invention includes a cermet composition represented by the formula (PQ)(RS) comprising: a ceramic phase (PQ) and a binder phase (RS) wherein, P is a metal selected from the group consisting of Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, W, Fe, Mn and mixtures thereof, Q is carbonitride, R is a metal selected from the group consisting of Fe, Ni, Co, Mn and mixtures thereof, S comprises at least one element selected from Cr, Al, Si and Y.

Abstract: The present invention discloses an improved apparatus and method for making a vacuum microwaved food product on a commercial scale. The invention discloses a rotatable carousel having an annular region for a food product for placement into a vacuum microwave. Food products such as strawberries or cheese can be placed into the annular region and dehydrated in a vacuum microwave.

Abstract: Apparel suitable for providing protection against noxious agents, wherein the apparel comprises a laminate material that provides a substantially effective barrier against the noxious agents. It is preferred that the laminate material comprises two or more layers, at least one of which is a barrier layer that is a substantially effective barrier against the noxious agents and at least one of which is a protective layer that protects the at least one barrier layer.

Abstract: A gas bearing spindle (2) for use in processing apparatus (1), for example ion implantation apparatus. The spindle (2) has a steel bearing surface (23) and a shaft (3) coated with chrome (3a) or another hard material.

Abstract: The present invention discloses an improved apparatus and method for making a vacuum microwaved food product on a commercial scale. The invention discloses a rotatable carousel having an annular region for a food product for placement into a vacuum microwave. Food products such as strawberries can be placed into the annular region and dehydrated in a vacuum microwave.

Abstract: The productivity of sandstone or carbonate formations is enhanced by contacting the formation with a deformable particulate and a HF-containing acidizing solution. The deformable particulates create a partial monolayer in the formation while the HF-containing acidizing solution differentially etches the rock around the deformable particulate. The surface of the formation is partially blocked from reaction with the acidizing solution by the creation of the partial monolayer. Conductive channels are therefore created on the surface of the formation. The deformable particulates deform on closure. As the closure stress increases, the formation faces compress the non-dissolved, sandwiched formation points. These points function as pillars of un-reacted formation and act similar to a partial monolayer of proppant, providing the highly conductive channels.

Abstract: A sports guard 1 for placing in a mouth of a user is disclosed. The guard 1 includes generally a base member 2 having a generally U-shaped form corresponding to the outline of a jaw of a user defining an upper channel 10 within which an upper row of teeth of a user can be received. The guard also discloses a teeth engaging element 3, associated with the channel 10 which is made of a material able to be user conformed or user moulded to the mouth of the user. The guard also includes shock absorption means associated with the base member 2 for absorbing impact shock. The shock absorption means comprises open channels in the base member 2 that function much like air springs. Further the base member advantageously comprises polyethylene mixed with up to 10% of EVA. The addition of EVA gives the guard more flexibility. The teeth engaging element is made of EVA.

Abstract: A method for treating obstructive sleep apnea includes providing MAD therapy via an adjustable mandibular advancement device structured to advance the position of the patient's lower jaw, providing CPAP therapy via a mask system structured to deliver a supply of pressurized air to a patient, and selectively adjusting the mask system and/or the mandibular advancement device to alternate and/or balance between CPAP therapy and MAD therapy.

Abstract: Optical correlators are discussed, suitable for in-vehicle distance measurement. The correlators use modulation sequences based on maximal length sequences. A number of different modulation sequences are obtained by generator (32) from a single maximal length sequence, either by adding a variable number of cycles to the end of the maximal length sequence or by starting the maximal length sequence at different points in the sequence.

Abstract: A composition comprising a nanoparticle and at least one adsorbate associated with the nanoparticle, wherein the adsorbate displays at least one chemically responsive optical property. A method comprising associating an adsorbate with a nanoparticle, wherein the nanoparticle comprises a shell surrounding a core material with a lower conductivity than the shell material and the adsorbate displays at least one chemically responsive optical property, and engineering the nanoparticle to enhance the optical property of the adsorbate. A method comprising determining an optical response of an adsorbate associated with a nanoparticle as a function of a chemical parameter, and parameterizing the optical response to produce a one-dimensional representation of at least a portion of a spectral window of the optical response in a high dimensional vector space.

Abstract: Techniques for video encoding and decoding channel switch frames (CSF) to enable acquisition and re/synchronization of the video stream while preserving compression efficiency is provided. Systems and methods to process multimedia data enabling channel switching are presented. The systems generate a CSF with one or more network adaptation layer (NAL) units as a random access point (RAP) frame. Back-to-back frames are transmitted which include the CSF and a non-RAP frame, each having the same frame ID number.

Abstract: Provided are a system, and article of manufacture for system recovery. An operating system and a backup copy of the operating system are both maintained in a partition of a computational device. A boot loader receives an indication to load the backup copy of the operating system. The boot loader loads the backup copy of the operating system. The computational device is rebooted with the loaded backup copy of the operating system.

Abstract: A packaging material which impart fragility capability and is easily manufactured and handled in preparing a product for shipment. The material is fabricated as a planar body having fold lines on which the body may be folded to encircle a product being packaged. The planar body is formed with locking features which enable a handler to easily secure the material about the packaged product and with defined openings facilitating handling.

Abstract: The present invention provides various methods for producing gel sheets in a continuous fashion. The embodiments of the present invention help reduce the time of producing gel sheets that is suitable for industrial manufacturing. Such gel sheets are used in manufacturing aerogel blankets used in a variety of applications including thermal and acoustic insulation.

Abstract: Provided are a method, system, and program for replicating a file. A file is copied to a target storage file system stored as a base file. A reference file comprising the copied file is generated at a local storage. An update is applied to the file at the local storage. A delta file is generated indicating differences between the updated file at the local storage and the reference file. A file system command is used to transmit the delta file to the target storage file system store to store in a directory of the target storage file system, wherein the file in the local storage is replicated at the target storage by a combination of the base file and the delta file.

Abstract: A method for drilling or cutting a pin (31) surrounded by solid material (32) includes the use of a water jet tool (10) having a nozzle (11) that is arranged at an angle with respect to a main body (12) of the water jet tool (10). The water jet is directed over a portion of the surface of the pin (31), and removes that portion thereby fragmenting the pin (31). In order to minimise damage to the surrounding material, the portions removed touches the interface between the pin and the surrounding solid material at a minimal number of points and over a minimal extent of the interface. The method is applicable in particular to the removal of pins (31) used in a press-fit for the securing of blades (3) on a turbine rotor (1). The method facilitates “in situ” removal of pins within a confined space in a short time and at reduced cost.