Patents by Inventor Christopher Justin PASETKA

Christopher Justin PASETKA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING HYPERTRIGLYCERIDEMIA
    Publication number: 20230212578
    Abstract: The present invention provides compositions comprising therapeutic nucleic acids such as siRNA that target ApoC3 and ANGPTL3 expression, lipid particles comprising one or more (e.g., a combination) of the therapeutic nucleic acids, and methods of delivering and/or administering the lipid particles (e.g., for treating hypertriglyceridemia in humans).
    Type: Application
    Filed: November 30, 2022
    Publication date: July 6, 2023
    Applicant: ARBUTUS BIOPHARMA CORPORATION
    Inventors: Ting CHIU, Narayanan HARIHARAN, Amy C. H. LEE, Christopher Justin PASETKA, Janet Ruth PHELPS, Nicholas Michael SNEAD, Andrew Anthony WIECZOREK
  • CONJUGATES AND METHODS FOR TREATING LIVER FIBROSIS
    Publication number: 20220387600
    Abstract: Provided herein are certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, a double stranded siRNA, and optional linking groups. Certain embodiments also provide synthetic methods useful for preparing the conjugates. The conjugates are useful to treat certain diseases, such as liver fibrosis, e.g., in the setting of NASH or ASH.
    Type: Application
    Filed: December 7, 2020
    Publication date: December 8, 2022
    Applicant: GENEVANT SCIENCES GMBH
    Inventors: James HEYES, Richard J. HOLLAND, Mark WOOD, Alan D. MARTIN, Christine ESAU, Margrit SCHWARZ, Xin YE, Alice Hoy Lam LI, Christopher Justin PASETKA, David CROWE, Steven TYLER
  • CONJUGATES AND METHODS FOR TREATING ACROMEGALY
    Publication number: 20220288214
    Abstract: Provided herein are certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, a double stranded siRNA, and optional linking groups. Certain embodiments also provide synthetic methods useful for preparing the conjugates. He conjugates are useful to treat certain diseases, such as acromegaly.
    Type: Application
    Filed: October 23, 2020
    Publication date: September 15, 2022
    Applicant: GENEVANT SCIENCES GMBH
    Inventors: Drew KONDRATOWICZ, James HEYES, Richard J. HOLLAND, Christine ESAU, Kevin MCCLINTOCK, Christopher Justin PASETKA, Mark WOOD, Alan D. MARTIN, Margrit SCHWARZ, David CROWE, Steven TYLER
  • COMPOSITIONS AND METHODS FOR TREATING HYPERTRIGLYCERIDEMIA
    Publication number: 20210047640
    Abstract: The present invention provides compositions comprising therapeutic nucleic acids such as siRNA that target ApoC3 and ANGPTL3 expression, lipid particles comprising one or more (e.g., a combination) of the therapeutic nucleic acids, and methods of delivering and/or administering the lipid particles (e.g., for treating hypertriglyceridemia in humans).
    Type: Application
    Filed: April 16, 2020
    Publication date: February 18, 2021
    Applicant: ARBUTUS BIOPHARMA CORPORATION
    Inventors: Ting CHIU, Narayanan HARIHARAN, Amy C. H. LEE, Christopher Justin PASETKA, Janet Ruth PHELPS, Nicholas Michael SNEAD, Andrew Anthony WIECZOREK
  • COMPOSITIONS AND METHODS FOR TREATING HYPERTRIGLYCERIDEMIA
    Publication number: 20180245077
    Abstract: The present invention provides compositions comprising therapeutic nucleic acids such as siRNA that target ApoC3 and ANGPTL3 expression, lipid particles comprising one or more (e.g., a combination) of the therapeutic nucleic acids, and methods of delivering and/or administering the lipid particles (e.g., for treating hypertriglyceridemia in humans).
    Type: Application
    Filed: March 21, 2016
    Publication date: August 30, 2018
    Applicant: PROTIVA BIOTHERAPEUTICS, INC.
    Inventors: Ting CHIU, Narayanan HARIHARAN, Amy C. H. LEE, Christopher Justin PASETKA, Janet Ruth PHELPS, Nicholas Michael SNEAD, Andrew Anthony WIECZOREK